Alunbrig 180mg Tablet is an anticancer agent used to treat non-small cell lung cancer (NSCLC), containing the active ingredient Brigatinib. It belongs to a class of drugs called tyrosine kinase inhibitors (TKIs) that block abnormal proteins responsible for cancer cell growth.

Alunbrig 180mg Tablet prescribed for patients with ALK-positive (anaplastic lymphoma kinase-positive) NSCLC who have shown disease progression or intolerance to previous ALK inhibitors. It helps prevent cancer cells from multiplying and spreading by targeting specific enzymes involved in tumor growth.

This drug is contraindicated in individuals with known hypersensitivity to Alunbrig 180mg Tablet or its components. Stop using it and consult your doctor immediately if you experience allergic reactions such as rash, swelling, or breathing difficulty.

If you are pregnant, planning pregnancy, or suspect pregnancy, consult your doctor before taking Alunbrig 180mg Tablet, as it may cause serious harm to the fetus. Similarly, consult your physician if you are breastfeeding or planning to breastfeed. Your doctor will assess your medical history and other medicines to ensure safe use.

Alunbrig 180mg Tablet is used for:

• Treatment of ALK-positive non-small cell lung cancer (NSCLC)

• Managing disease progression in patients previously treated with other ALK inhibitors

• Reducing tumor growth and preventing metastasis
  

Brigatinib works by selectively inhibiting the activity of the ALK protein and other kinases involved in cancer cell proliferation. By blocking these enzymes, it helps prevent tumor cells from multiplying, spreading, and surviving, thereby slowing the progression of lung cancer.

Alunbrig 180mg Tablet may interact with:

• Strong CYP3A inhibitors (e.g., ketoconazole) that can increase brigatinib levels in the blood

• CYP3A inducers (e.g., rifampin) that can reduce its effectiveness

• Other anticancer drugs, increasing the risk of side effects like heart rhythm problems or lung toxicity

Always inform your doctor of all other medications, including over-the-counter drugs and herbal supplements.

• Store below 30°C in a dry place

• Protect from direct sunlight and moisture

• Keep out of reach of children

• Do not use after the expiry date mentioned on the pack

• Take exactly as prescribed by your oncologist

• Usually taken once daily, with or without food

• Swallow the tablet whole; do not crush, chew, or split

• Follow the prescribed dosage schedule strictly

• If a dose is missed, take it as soon as you remember unless it’s near the next dose. Do not double the dose.

Common side effects:

• Nausea

• Fatigue

• Diarrhea

• Increased blood pressure

• Cough
  
  

Serious side effects (seek medical help immediately):

• Lung problems (pneumonitis, interstitial lung disease)

• Liver enzyme abnormalities

• Severe allergic reactions (rash, swelling, difficulty breathing)

• High blood pressure

• Visual disturbances
  

• Take Alunbrig 180mg Tablet at the same time every day for consistent effect

• Keep regular medical follow-ups for monitoring side effects and treatment progress

• Report any unusual symptoms, especially breathing difficulties, to your doctor immediately

• Do not stop treatment suddenly without medical advice