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Aximac 5mg Tablet
Last updated on 09 Nov 2026 | 04:44 AM (IST)
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Introduction
Aximac 5 mg Tablet is an anticancer drug belonging to the class of tyrosine kinase inhibitors, containing the active ingredient Axitinib. Commonly searched as aximac 5mg, it is primarily used to treat advanced kidney cancer, also known as renal cell carcinoma, which originates in the cells of the kidney. Some users may confuse it with an aximac tablet for blood pressure or aximac tablet for hypertension, but this medicine is not used for those conditions. Instead, amlodipine 5 mg tablet uses are related to blood pressure control, which is a different category of medication.
It is not recommended to undergo surgical procedures while on treatment with Aximac 5mg Tablet due to a high risk of bleeding. Inform your doctor before any surgery or dental procedures. Seek immediate medical attention if you experience symptoms such as itching, vision changes, confusion, or dizziness. Like all cancer treatments, there can be aximac 5mg tablet side effects, which should be closely monitored.
This medicine may harm an unborn baby. Inform your healthcare provider if you are pregnant or planning to conceive. Both men and women are advised to use effective contraception during treatment and for at least one week after the last dose. Avoid breastfeeding while taking Aximac 5mg Tablet, as it may affect the baby’s growth and development through breast milk.
If you experience symptoms such as mouth sores, unexplained weight loss, or itchy skin, consult your doctor promptly. Aximac 5mg Tablet is not recommended for children and adolescents under 18 years of age.
Uses
Advanced kidney cancer
How Aximac 5mg Tablet works
It belongs to the category of tyrosine kinase inhibitors, which interferes with the growth of blood vessels inside the cancer cellS. It also acts against a protein called receptor tyrosine kinases to interrupt cell signalling, ultimately stopping the growth and spread of cancer cells.
Interaction of Aximac 5mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Aximac 5mg Tablet and reduce effectiveness by causing undesirable side effects.
Storage Conditions
Store Aximac 5mg Tablet in the original package at room temperature (20°C to 25°C).
Keep it out of reach from children.
How to take Aximac 5mg Table
Your doctor will decide the dose and duration of Aximac 5mg Tablet based on the disease condition. Always take this medicine as prescribed by your doctor. The recommended starting oral dose of Aximac 5mg Tablet is 5 mg twice daily. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Safety advice
Pregnancy
Aximac 5mg Tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Breast Feeding
It is unsafe to breastfeed during the treatment with Aximac 5mg Tablet because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Lungs
It is not known whether Aximac 5mg Tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Inform your doctor if you have any liver problems before taking Aximac 5mg Tablet. Regular monitoring of liver function tests is recommended.
Alcohol
Consuming alcohol may affect the effectiveness of Aximac 5mg Tablet. Stop consuming alcohol if you are taking this medicine.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Aximac 5mg Tablets, it may cause dizziness and impair your concentration.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Extreme tiredness and swelling
Pressure or pain in the chest, arms, back, neck or jaw
Breathlessness
Numbness and weakness on one side of the body
Difficulty speaking or communicating verbally
Headache
Vision changes or dizziness
Serious bleeding problems like black tarry stools, bloody cough or bloody sputum
Severe stomach pain
High blood pressure
Common
Kidney problems
Dehydration
Hyper-active thyroid gland
Sore throat
Loss of appetite
Joint pain
Lack of energy
Weight loss
Constipation
Mouth sores
Skin itching, redness of skin and hair loss
Expert Tips
Bexinib 1 mg Tablet may cause dizziness, weakness, confusion, or tiredness.
Avoid driving or operating heavy machinery if you experience these symptoms.
Do not consume grapefruit or grapefruit juice, as it can increase the medicine’s levels in the body.
Some formulations of gefitinib may contain lactose as an inactive ingredient.
If you have lactose intolerance, inform your doctor before starting treatment.
Lactose intolerance may cause symptoms like bloating and abdominal pain.
FAQs
Q1.
What are the most common side effects of Aximac 5mg Tablet?
The common side effects that are likely to occur while you are on the treatment with Aximac 5mg Tablet are high blood pressure, diarrhoea, nausea, vomiting, constipation, indigestion, soreness in the mouth, tongue or throat, shortness of breath, cough, tiredness, weakness, dehydration, loss of appetite, joint pain, weight loss, headache, muscle pain, nose bleeding, tinnitus, itching, hair loss, dizziness, and inflammation of the gallbladder.
Q2.
Is it safe to use Aximac 5mg Tablet during pregnancy?
Aximac 5mg Tablet may cause harm to an unborn baby. Tell your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby.
Q3.
Is it safe to undergo a surgery during treatment with Aximac 5mg Tablet?
Aximac 5mg Tablet is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and tell your physician before you undergo surgery or dental procedures. Your healthcare provider will suggest stopping the medication a day prior to surgical procedure.
Q4.
What should you not take with Aximac 5mg Tablet?
It is not recommended to take grapefruit and grapefruit juice while on treatment with Aximac 5mg Tablet. Tell your healthcare provider if you are taking any prescription medicines, over the counter drugs, vitamins or herbal supplements.
Q5.
What are all the dosage forms and strengths available for Aximac 5mg Tablet?
Aximac 5mg Tablet is available in the form of film-coated tablets in the doses 1mg, 3mg, 5mg and 7mg. The usual recommended dose is 5mg twice a day.
Fact Box
Molecule name | Axitinib |
Therapeutic class | Anticancer |
Pharmacological class | tyrosine kinase inhibitors |
Indications | Advanced kidney cancer |
References
Pfizer, [Revised on 13th Jan 2020] [Accessed on 23rd March 2023], https://www.pfizer.ca/sites/default/files/202001/INLYTA_PM_Approved_03Jan2020_E_DC.pdf
Pfizer Labs, Electronic Medicines Compendium(EMC), [Revised on Mar 2021] [Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.4325.pdf
Pfizer, Fact sheet, [Revised on Sep 2012] [Accessed on 23rd March 2023], https://cdn.pfizer.com/pfizercom/news/esmo/renal_cell_carcinoma_fact_sheet.pdf
Annex I summary of Product Characteristics - European Medicines Agency. Available at:https://www.ema.europa.eu/en/documents/product-information/inlyta-epar-product-information_en.pdf (Accessed on March 25, 2023).
Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
Disclaimer
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 09 Nov 2026 | 04:44 AM (IST)
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