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Azafect 100mg injection is used for treating adults with Myelodysplastic syndrome (MDS) and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant. In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer that is caused by the release of incompletely formed blood cells into the bloodstream.

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Treatment of Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
Intermediate-2 and High-risk Myelodysplastic syndrome (MDS)

"}},{"id":"049abea9-0360-4165-94c2-9f3c346538a3","type":"PARA","position":3,"content_placement":1,"data":{"heading":"Therapeutic Effects of Azafect 100mg Injection","text":"

In MDS and AML, the development of tumor cells is caused by the process of transcriptional repression of various genes, which is due to hypermethylation of DNA. Transcriptional repression is a process where proteins bind directly or indirectly to DNA and control the activity of copying a specific gene or a set of genes. The active form of Azafect 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells, and exhibits a toxic effect on cancer cells.

"}},{"id":"eba7bdbc-d961-485e-9c06-52ddaf615c2d","type":"PARA","position":4,"content_placement":1,"data":{"heading":"Interaction of Azafect 100mg Injection with other drugs","text":"

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azafect 100 mg injection and cause undesirable side effects.

"}},{"id":"e095ad55-f216-4539-a433-1abcd2d3c1ff","type":"PARA","position":5,"content_placement":1,"data":{"heading":"More Information about Azafect 100mg Injection","text":"

Store at room temperature (15-30°C). If the product is reconstituted, it must be used immediately; if not, store at 2-8°C for not more than 8 hours. Keep the injection out of sight and reach of children.

"}},{"id":"0bbc4ee6-a0d7-4a51-9bcc-bfd69beadd4f","type":"PARA","position":6,"content_placement":1,"data":{"heading":"How to consume Azafect 100mg Injection","text":"

Take Azafect 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight, and general condition. Azafect 100mg Injection shall be given under the skin of your thigh, stomach, or upper arm.

"}},{"id":"13493d88-a041-4d85-820d-89f9e656864e","type":"SAFETY_ADVICE","position":7,"content_placement":2,"data":{"heading":"Safety Advice for Azafect 100mg Injection","safety_list":[{"id":"c440f6ac-f081-4459-b202-24aa73bd5b38","advice":"Breast Feeding","tag":"unsafe","description":"

Breastfeeding is not intended for patients on Azafect 100mg Injection therapy. Consult your physician for advice.

","imageUrl":"https://assets.mrmed.in/others/file-1674132409667-45039420-Breatfeeding.jpg"},{"id":"bc2a8bbb-e10b-43d0-a0d9-8a5b5f56d6a9","advice":"Alcohol","tag":"Consult your doctor","description":"

It is not known whether it is safe to consume alcohol with Azafect 100mg Injection. Please consult your doctor.

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Inform your physician if you have been told that you have a tumor in the liver cells.

","imageUrl":"https://assets.mrmed.in/others/file-1674132424807-417765861-Liver.jpg"},{"id":"47c3ccdd-0986-4cb7-a36a-46e89089b9c7","advice":"Lungs","tag":"Consult your doctor","description":"

It is not known whether it is safe to administer Azadine 100mg Injection in lung failure patients. Please consult your doctor.

","imageUrl":"https://assets.mrmed.in/others/file-1674132427859-226731771-Lungs.jpg"},{"id":"29f5e13b-de8b-42bb-9f7e-e4124f0a4927","advice":"Driving","tag":"unsafe","description":"

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking Azafect 100 mg injection.

","imageUrl":"https://assets.mrmed.in/others/file-1674132431331-421990512-Driving.jpg"},{"id":"9f6aa71d-75a6-43e6-95b4-ae5c6cc33a5b","advice":"Pregnancy","tag":"unsafe","description":"

Azafect 100mg Injection could be harmful to the unborn fetus. Inform your physician if you are pregnant or planning to get pregnant.

","imageUrl":"https://assets.mrmed.in/others/file-1674132401469-949914510-Pregnancy.jpg"}]}},{"id":"cf54fe73-678d-4b69-9f4b-164f9885e1c5","type":"PARA","position":8,"content_placement":1,"data":{"heading":"Side Effects of Azafect 100mg Injection","text":"$22"}},{"id":"6afe9ba7-bdd9-4aa5-bda5-917c06b2ef06","type":"PARA","position":9,"content_placement":1,"data":{"heading":"Word of Advice","text":"

Inform the doctor if the patient has any allergy reactions, respiratory problems, kidney, liver, or heart problems, and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breastfeeding mothers as this medicine causes harmful effects on the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight, and general condition. It is administered under the skin of your thigh, stomach, or upper arm.

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How to use Azafect 100mg injection?

","answer":"

Take Azafect 100mg injection only under the supervision of the physician. Doctors will decide the dose based on patient's height, weight, and general condition. Azafect 100mg injection is administered under the skin of your thigh, stomach, or upper arm.

"},{"id":"f2ebc54f-4d2b-4fa1-a4e2-6f5e14f82e07","question":"

Does Azafect 100mg injection cause hair loss?

","answer":"

No, Azafect 100mg injection does not cause hair loss even after using it for a prolonged period of time.

"},{"id":"7f15fbcc-c364-4932-ac80-90a74e6279de","question":"

How does Azafect 100mg injection?

","answer":"

Azafect 100mg injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.

"},{"id":"7e3d6f5e-f378-4490-ada3-c627d33eb139","question":"

Is Azafect 100mg injection chemotherapy?

","answer":"

Yes. Azafect 100mg injection is chemotherapy, and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases growth and multiplication (cytotoxic effect).

"},{"id":"9efaba4e-b3bb-4df2-affa-4cb8619186eb","question":"

What are the side effects of Azafect 100mg injection?

","answer":"

The common side effects of Azafect 100mg injection are nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of the skin, dizziness, joint pain, headache, sore throat, and nose.

"},{"id":"7ea9cda7-a3d2-4b2b-bd36-fdeea05ba60a","question":"

Is it safe to drive after taking an Azafect 100mg injection?

","answer":"

It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machinery after taking this medication.

"}]}},{"id":"b229f5cc-f40f-4569-a390-e7d9ef12040d","type":"PARA","position":11,"content_placement":3,"data":{"heading":"Fact Box of Azafect 100mg Injection","text":"

Molecule name: Azacitidine

Therapeutic class: Anti-metabolites

Pharmacological class: Anti-Neoplastics

Indications:

1. Treat advanced or metastatic non-small lung cancer (NSCLC),

2. To Treat Advanced or metastatic pancreatic cancer.

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MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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