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BAVENCIO 200MG/10ML INJECTION_1
BAVENCIO 200MG/10ML INJECTION_2
BAVENCIO 200MG/10ML INJECTION_1
17% Off

Bavencio 200mg Injection 10ml

Prescription Required

cold-chain

Salt Composition : Avelumab

Manufacturer : MERCK LTD

Origin of Medicine : Germany

MRP: 146800
Price :121705
You Save :25095 (17%)

1 Vial(s) Of 10ml

Prepaid Only. Non-Returnable

PAP Information :    Buy 1, Get 2 Free. Contact us for latest updates.


Patient Assistance Programs
Know About PAP

Merck offers Patient Assistance Programs for Bavencio wherein patients will get 2 free vials on purchase of a single vial. This patient assistance is subject to Merck's approval, submission of valid documents including prescription and patient details. We provide proper guidance assistance to patients getting enrolled in Merck's patient assistance program.

Patient Assistance Programs

Merck offers Patient Assistance Programs for Bavencio wherein patients will get 2 free vials on purchase of a single vial. This patient assistance is subject to Merck's approval, submission of valid documents including prescription and patient details. We provide proper guidance assistance to patients getting enrolled in Merck's patient assistance program.

Introduction to Bavencio 200mg Injection 10ml

Bavencio 200mg/10ml injection contains the active ingredient avelumab. It is an antineoplastic drug that belongs to the class of medications called PD-1/PD-L1 (programmed death ligand-1) inhibitors. It is used to treat Merkel cell carcinoma, a rare type of skin cancer that has spread to other body parts in adults and children 12 years and older. It is also indicated to treat urothelial carcinoma, cancer that originates in the urinary tract that has spread to nearby tissues or other body parts of the body in people whose cancer worsened during or within 12 months after it was treated with other anticancer medications.  

It is also used in combination with other anticancer medicines to treat renal cell carcinoma, a type of kidney cancer that has spread to other body parts. PD-L1 is found on the surface of certain cancer cells and helps protect them from the immune system. It works by slowing or stopping the growth and spread of the cancer cells.  Do not take Bavencio 200mg/10ml injection if you are allergic to avelumab or any other ingredients of this medicine. Inform your physician if you have liver diseases, hepatitis B, HIV/AIDS, or other immune diseases before initiating the therapy. 

This medicine is not recommended for children and adolescents below 18. If you suffer from any of the reactions like infusion-related reactions, inflammation of your lungs, liver, pancreas, watery stools, or diarrhea, inform your doctor immediately and seek medical attention. Bavencio 200mg/10ml injection should not be used in pregnant and breastfeeding women. Inform your physician if you are pregnant or breastfeeding. Use effective contraception throughout the therapy to avoid pregnancy. The common adverse reactions are tiredness, muscle pain, diarrhea, nausea, rash, decreased appetite, urinary tract infection, and swelling in the body parts.


Uses of Bavencio 200mg Injection 10ml

  • Merkel cell carcinoma
  • Urothelial carcinoma
  • Renal cell carcinoma

Therapeutic Effects of Bavencio 200mg Injection 10ml

Bavencio 200mg/10ml injection is a monoclonal antibody (a type of protein) that attaches to a specific target in the body called PD-L1. It binds to PD-L1 and blocks this protective effect, allowing the immune system to attack the tumor cells. It also induces antibody-dependent cell-mediated cytotoxicity, ultimately leading to cancer cell death.  


Interaction of Bavencio 200mg Injection 10ml with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Bavencio 200mg/10ml injection and reduce its effectiveness by causing undesirable side effects. 


More Information about Bavencio 200mg Injection 10ml

  • Store in a refrigerator (2°C to 8°C).
  • Do not freeze. Store in the original package to protect from light.
  • keep the injection away from the reach of children and pets.
  • If you have missed any dosing appointments, inform your doctor and schedule immediately.

How to consume Bavencio 200mg Injection 10ml

It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). This will take one hour. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors. 


Safety Advices for Bavencio 200mg Injection 10ml

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Pregnancy

  

Bavencio 200mg/10ml injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 1 months after your last dose is necessary.  

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Bavencio 200mg/10ml injection because the medicine passes into the breast milk in small amounts and may harm your baby. 

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Lungs

  

It is unknown whether Bavencio 200mg/10ml injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

Bavencio 200mg/10ml injection is safe to administer in patients with liver problems. Dose adjustments are not necessary. However, inform your physician if you have any liver diseases or problems before initiating the therapy. 

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Alcohol

  

It is unknown whether consuming alcohol is safe during the treatment with Bavencio 200mg/10ml injection. Inform your doctor if you are a chronic drinker. 

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Driving

  

Bavencio 200mg/10ml injection may make you feel tired, dizzy, or sleepy. It is unsafe to drive or operate heavy machinery after taking this medicine. 


Side Effects of Bavencio 200mg Injection 10ml

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Common 

  • Increased blood pressure
  • Swelling in the legs and feet
  • Skin rash
  • Abdominal pain
  • Decrease in appetite
  • Diarrhea
  • Nausea
  • Decreased RBC counts
  • Muscle pain
  • Cough, shortness of breath
  • Difficulty in talking
  • Tiredness 

Serious 

  • Heart problems
  • Severe skin reactions
  • Thyroid problems
  • Liver injury
  • Visual impairment
  • Infusion reactions

Word of Advice

Report symptoms of infection, anemia, or bleeding immediately to your doctor. Do not breastfeed during the treatment and for 1 month after the last dose. Inform your doctor if you have kidney disease, liver disease, heart disease, diabetes, lung or breathing problems, or stomach problems before initiating the therapy. Do not stop taking the injection without consulting the physician. Stopping your treatment may stop the effect of the medicine. Your doctor may ask you to do certain tests to check for the effectiveness of the therapy and to monitor any unwanted side effects. 


FAQs

Q 1. How long should I have to take Bavencio 200mg/10ml injection?

Bavencio 200mg/10ml injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.

Q 2. Can I take vitamin supplements with Bavencio 200mg/10ml injection?

Certain medications may interact with the effectiveness of Bavencio 200mg/10ml injection including prescription, over-the-counter medicines, vitamin or nutritional supplements, and herbal products. Inform your physician about your medication history.

Q 3. Is Bavencio 200mg/10ml injection cardiotoxic?

Heart problems like cardiac arrest and congestive heart failure may occur in patients receiving this medicine for the long term. Inform your physician of any pre-existing heart disorders before initiating the treatment.

Q 4. What is Bavencio 200mg/10ml injection patient information leaflet?

The FDA has a patient information leaflet containing a summary of the essential scientific information needed for the safe and effective use of the drug. Read the information leaflet thoroughly before starting the therapy.

Q 5. What are the infusion reactions of Bavencio 200mg/10ml injection?

Signs of shortness of breath, wheezing, chills or shaking, rash, flushing, low blood pressure, dizziness, fatigue, nausea, fever, back pain, and abdominal pain are the infusion reactions that may cause due to the Bavencio 200mg/10ml injection administration. Inform your physician and seek medical attention immediately if you face these reactions after administering the injection.


Fact Box of Bavencio 200mg Injection 10ml

Molecule name: Avelumab

Therapeutic class: Antineoplastics

Pharmacological class: PD-1, PD-L1 inhibitors

Indications: 

1. Merkel cell carcinoma

2. Urothelial carcinoma 

3. Renal cell carcinoma


References

  1. Bavencio 20 mg/mL concentrate for solution for infusion - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Revised February 2022. Accessed May 4, 2023. http://www.medicines.org.uk/emc/product/8453/smpc
  2. BAVENCIO-Avelumab Injection.; Revised June 2020. Accessed May 4, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/761049s009lbl.pdf
  3. Douglas F. Lake and Adrienne D. Briggs, Immunopharmacology, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 977-1002.

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