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Biobin 1gm Injection
Salt Composition : Cytarabine
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
1 Vial(s) Of 10ml
Introduction to Biobin 1gm Injection
Biobin 1gm injection contains the active substance Cytarabine. It is an antineoplastic drug that belongs to the class antimetabolite. It is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain).
Do not take Biobin 1gm injection if you are allergic to Cytarabine or any other ingredients of this medicine. Inform your physician if you have difficulties in body coordination, or taking any other anti-cancer medications, decreased bone marrow functioning, have liver problems, or have undergone dialysis immediately before or after treatment with this medicine.
Biobin 1gm injection may cause an increased uric acid level in your blood, your doctor will tell you if you need to take any medicine to control this. Notify your physician if you have sudden signs of allergy, such as rash, itching, or hives on the skin, swelling of the face, lips, mouth, or throat, shortness of breath, or wheezing. It is unknown whether this medicine can be administered in patients with kidney failure, inform your doctor if you have any kidney diseases.
Uses of Biobin 1gm Injection
- Acute myeloid leukemia (AML)
- Chronic myelogenous leukemia (CML)
- Meningeal leukemia
Therapeutic Effects of Biobin 1gm Injection
Biobin 1gm injection is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body.
Interaction of Biobin 1gm Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, vaccines, and herbal products. Certain medications may interact with the effects of Biobin 1gm injection and reduce its effectiveness by causing undesirable side effects. Inform your physician if you are using digoxin.
More Information about Biobin 1gm Injection
- Store Biobin 1gm injection at room temperature (25°C)
- Do not refrigerate or freeze.
- Keep the injection away from the reach of children and pets.
- If you forgot to take a dose on the scheduled day, contact your physician and reschedule the dose.
- Do not take a double dose to make up for a forgotten dose.
How to consume Biobin 1gm Injection
Biobin 1gm injection will be given to you in a hospital setting by a trained healthcare professional. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors.
Safety Advices for Biobin 1gm Injection
Biobin 1gm injection is unsafe to administer in pregnant women because it may cause birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6 months after your last dose is necessary.
Breastfeeding is not recommended in patients taking Biobin 1gm injection because the medicine passes into the breast milk in small amounts and may harm your baby.
It is unknown whether Biobin 1gm injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
It is unknown whether Biobin 1gm injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.
It is not known whether it is safe to consume alcohol with Biobin 1gm injection. Please consult your doctor.
Biobin 1gm injection does not affect your ability to drive or use machinery. If you are affected, consult your doctor for more advice.
Side Effects of Biobin 1gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Loss of appetite, abdominal pain
- Swallowing difficulties
- Nausea, vomiting
- Inflammation or ulceration in the mouth or anus
- High blood uric acid levels
- Hair loss
- Skin rashes
- Speaking difficulties
- Inflammation in the vein
- Swelling and irritation of the skin
- Increased blood uric acid levels
- Blisters of the skin
- Irregular heartbeat
- Lung diseases
- Kidney problems
Word of Advice
During the treatment with Biobin 1gm injection, the administration of vaccines is not advised. If required, consult your doctor. This medicine may cause infertility in men and women. Your doctor will do blood tests regularly to check whether the medicine works. Inform your physician if you have any ulcers or bleeding in the stomach or intestines. This medicine may make you bleed or bruise easily; take precautions to prevent the illness.
Q 1. What should I monitor when taking Biobin 1gm injection?
Biobin 1gm injection may cause neurological problems, monitor for speech disturbances, eye problems, and coordination problems. Inform your physician if you have noticed any of these problems.
Q 2. What if I overdose Biobin 1gm injection?
High doses of Biobin 1gm injection can worsen side effects like sores in the mouth or may decrease the number of WBC and platelets in the blood, damages to nerves, severe lung problems, heart problems. Inform your physician if you experience any of the symptoms.
Q 3. Is Biobin 1gm injection toxic to the liver?
The safety of Biobin 1gm injection to the liver has not been well established. The drug may cause a few liver-related side effects. Inform your physician if you have liver diseases before initiating the treatment.
Q 4. Should I have to refrigerate Biobin 1gm injection?
No, do not refrigerate or freeze Biobin 1gm injection. The injection should be stored at room temperature 20°C to 25°C.
Q 5. Is Biobin 1gm injection toxic to the brain?
Intravenous administration of Biobin 1gm injection can cause peripheral neuropathy. Inform your physician if you have any symptoms of pain, numbness or weakness in the hands and feet, digestive and urination problems.
Fact Box of Biobin 1gm Injection
Molecule name: Cytarabine
Therapeutic class: Antineoplastics
Pharmacological class: Antimetabolite
1. Acute myeloid leukemia
2. Chronic myelogenous leukemia
3. Meningeal leukemia
- Cytarabine Injection. [cited 2020 Dec 3]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/071868s032lbl.pdf
- Cytarabine Injection Solution 100 mg/ml - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [revised on 2020] [cited 2023 Mar 30]. Available from: https://www.medicines.org.uk/emc/product/1570/smpc
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1698 – 1699.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 864 - 865.
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