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Canrib 150mg Tablet
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹8385
MRP: ₹12938
(You Save ₹4553)
60 TABLET(s) IN A BOTTLE
Canrib 150mg Tablet is a prescription medicine used to treat certain types of cancer, including chronic myeloid leukaemia (CML) and gastrointestinal stromal tumours (GIST). It contains nilotinib, a tyrosine kinase inhibitor that works by blocking specific proteins responsible for cancer cell growth, helping to slow or stop the progression of the disease. Canrib 150mg Tablet should be taken under strict medical supervision as part of a comprehensive cancer treatment plan.
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Introduction to Canrib 150mg Tablet
Canrib 150mg Tablet belongs to the class of cancer medications known as PARP (poly [adenosine diphosphate-ribose] polymerase inhibitor) inhibitors, containing the active ingredient Olaparib. It is used to treat pancreatic, and prostate cancer. This medication can be given alone or in combination with other anticancer medications.
It is not recommended to take olaparib if you are allergic to the active compound and other ingredients of the medicine. Speak with your doctor immediately if you experience breathlessness, chest pain, rapid heart rate, fever, cough, or wheezing. Your healthcare provider will conduct blood tests before and every month during the treatment, as this medicine could reduce the counts of RBC, WBC, and platelets. Tell your healthcare provider before starting treatment, if you have been diagnosed with problems in your lungs, liver, heart, or kidneys.
It is not advised to use this medication while pregnant since it may harm the fetus and cause miscarriage. Therefore, for women of reproductive age, it is recommended to get a pregnancy test before beginning this medication. It is preferable to keep using birth control for at least six months after treatment is finished. While receiving treatment, it is not advised to breastfeed your child because it is unknown if Canrib 150mg Tablet will find its way into the breast milk. Men are not advised to donate sperm for at least 3 months after the treatment is finished. It is necessary to inform your doctor about all the medicines you are taking including prescription, over the counter drugs, vitamins and supplements.
Uses of Canrib 150mg Tablet
- Treatment of Prostate cancer
- Metastatic Pancreatic cancer
Therapeutic Effects of Canrib 150mg Tablet
Canrib 150mg Tablet works by inhibiting the enzyme poly (ADP-ribose) polymerase (PARP), which plays a role in repairing damaged DNA in cells. By inhibiting PARP, Canrib 150mg Tablet prevents cancer cells from repairing their DNA, leading to cell death. This targeted approach is especially effective in cancers with defective DNA repair mechanisms.
Interaction of Canrib 150mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Canrib 150mg Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Canrib 150mg Tablet
- Store Canrib 150mg Tablet in the original package at room temperature (20°C to 25°C).
- Keep it out of reach from children.
How to consume Canrib 150mg Tablet
The medicine will be prescribed to you by a healthcare professional in a hospital setting. Canrib 150mg Tablet is available as a tablet to be taken with or without food, as directed by your healthcare provider. The dose will be decided by your healthcare professional based on your conditions. Avoid crushing, opening, or dissolving the tablet and swallow it whole with a glass of water. Take the Canrib 150mg Tablet at the same time every day.
Safety Advice for Canrib 150mg Tablet
Breast Feeding
It is unknown whether Canrib 150mg Tablet passes into the breast milk. It is not recommended to nurse a child during and after 1 month of completion of therapy. Please consult your doctor before breastfeeding.
Alcohol
It is unknown whether consuming alcohol interacts with the Canrib 150mg Tablet. Please consult your doctor for more advice.
Liver
It is unknown whether Canrib 150mg Tablet is safe in individuals with liver disorders. Inform your physician if you have any liver problems before starting the treatment.
Lungs
Consult your doctor if you have any lung diseases before starting the treatment with Canrib 150mg Tablet.
Driving
Canrib 150mg Tablet may have an impact on your ability to operate machinery and drive. It is not recommended to operate machinery or drive vehicles if you experience lightheadedness, weakness, or exhaustion.
Pregnancy
It is not recommended to take Canrib 150mg Tablet during pregnancy as it may harm your unborn baby. It is necessary to inform your doctor if you are pregnant or planning to become pregnant.
Side Effects of Canrib 150mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Neutropenia
- Acute myeloid leukemia
- Leukopenia
- Thrombocytopenia
- Lung problems
Common
- Shortness of breath
- Nausea
- Vomiting
- Fatigue
- Dyspepsia
- Loss of appetite
- Dizziness
- Diarrhoea
- Headache
Word of Advice
Canrib 150mg Tablet can lower blood cell counts, thus it's best to get blood tests done at regular intervals. When undergoing this therapy, stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside. Canrib 150mg Tablet should not be stopped without first talking to your doctor. When using this medication, stay away from grapefruit juice as it may raise your blood levels of the drug. It is recommended to inform your doctor about other anticancer drugs you have been taking. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Canrib 150mg Tablet.
Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately. With proper monitoring and management, Canrib 150mg Tablet can be an effective treatment option for certain types of cancer.
FAQs about Canrib 150mg Tablet
Q1.
Can Canrib 150mg Tablet be taken during pregnancy or breastfeeding?
Canrib 150mg Tablet may harm an unborn baby and should not be used during pregnancy. It is also not recommended while breastfeeding, as it may pass into breast milk and harm the nursing infant.
Q2.
What are Canrib 150mg Tablet typical side effects?
Nausea, vomiting, lethargy, diarrhea, appetite loss, and blood cell count abnormalities are typical adverse effects.
Q3.
Are there any dietary restrictions I need to follow while on Canrib 150mg Tablet?
There are no specific dietary restrictions associated with Canrib 150mg Tablet. However, it's essential to maintain a healthy and balanced diet to support your overall well-being during treatment. It is recommended to avoid grape juice as it increases the blood drug concentration.
Q4.
Is Canrib 150mg Tablet used as a standalone treatment in cancers?
Canrib 150mg Tablet is usually indicated as maintenance therapy after a person completes a platinum-based chemotherapy regimen for ovarian cancer. However, newer studies are evaluating its solitary efficacy in treating different types of cancers.
Q5.
Can I drive or operate machinery while taking Canrib 150mg Tablet?
Canrib 150mg Tablet may cause side effects such as dizziness or fatigue, which could impair your ability to drive or operate machinery safely. If you're unsure, it's best to consult with your healthcare provider for personalized advice based on your specific situation.
Fact Box of Canrib 150mg Tablet
| Molecule Name: Olaparib | Therapeutic class: Antineoplastic agents |
Pharmacological class: Poly Adenosine Diphosphate-Ribose Polymerase (PARP) inhibitor | Indications: 1. Treatment of Prostate cancer 2. Metastatic Pancreatic cancer |
| Dosage form: Tablets | Habit forming: No |
References
- Lynparza, United States Food and Drug Administration (USFDA), [Revised on May 2020], [Accessed on March 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208558s014lbl.pdf
- AstraZeneca UK Limited, European Medicines Compendium (emc), [Revised on August 2023], [Accessed on March 2024], https://www.medicines.org.uk/emc/files/pil.9204.pdf
- AstraZeneca Pharmaceuticals LP, [Revised on November 2023], [Accessed on March 2024], https://den8dhaj6zs0e.cloudfront.net/50fd68b9-106b-4550-b5d0-12b045f8b184/00997c3f-5912-486f-a7db-930b4639cd51/00997c3f-5912-486f-a7db-930b4639cd51_viewable_rendition__v.pdf
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Author Details
Written By
Dr. Thamizhakaran K. S.
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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