Cernos Gel is used for:

• Primary hypogonadism: A condition in which the testicles produce insufficient testosterone due to a congenital or acquired problem.

• Hypogonadotropic hypogonadism: A condition in which the hypothalamus or pituitary gland does not provide the hormonal signals needed for normal testosterone production.

The doctor determines whether Cernos Gel is appropriate based on symptoms, blood testosterone levels and the underlying cause of testosterone deficiency. The dose and duration of treatment are decided individually.

Cernos Gel contains Testosterone, a hormone that binds to androgen receptors in the body. This activates processes involved in the development and maintenance of male sexual characteristics and other functions regulated by testosterone.

By replacing insufficient testosterone, Cernos Gel helps restore hormone levels towards the normal range and may improve symptoms associated with testosterone deficiency.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you take. Certain medicines can interact with testosterone and may require additional monitoring.

• Insulin and other diabetes medicines: Testosterone may affect blood glucose levels and reduce insulin requirements in some people with diabetes. Blood glucose levels may need closer monitoring.

• Anticoagulants (blood-thinning medicines): Testosterone may alter the effects of anticoagulants such as warfarin. Your doctor may monitor blood clotting more frequently and adjust treatment if necessary.

• Corticosteroids: Using testosterone with corticosteroids may increase fluid retention. This requires particular care in people with heart, kidney or liver conditions.

• Other testosterone products or anabolic androgenic steroids: Combining these products may increase testosterone exposure and the risk of adverse effects. Do not combine them unless your doctor specifically advises it.

• Store Cernos Gel at approximately 25°C, following the instructions on the product packaging.

• Do not freeze the gel.

• Protect the product from excessive heat and direct sunlight.

• Keep the tube properly closed when not in use.

• Keep Cernos Gel out of the sight and reach of children.

• Apply Cernos Gel exactly as prescribed by your doctor. The dose and frequency depend on your testosterone levels and treatment response.

• Apply the prescribed amount to clean, dry and healthy skin over the shoulders or upper arms, following the product instructions.

• Do not apply the gel to the penis, scrotum, chest or other areas not specified in the product instructions.

• Wash your hands thoroughly with soap and water immediately after applying the gel.

• Allow the application site to dry before covering it with clothing.

• Avoid direct skin-to-skin contact between the treated area and other people. Before anticipated skin contact, wash the application site thoroughly with soap and water.

• Women and children must not come into contact with the gel or unwashed application sites because testosterone can be transferred through skin contact.

• Avoid smoking and contact with open flames until the gel has dried completely, as testosterone gels may be flammable.

• Follow your doctor's advice about bathing, swimming or washing the application site after application.

Cernos Gel may cause side effects in some people, although not everyone experiences them.

Common side effects

• Acne

• Redness or irritation at the application site

• Skin rash

• Headache

• Increased blood pressure

• Changes in prostate-specific antigen (PSA) levels

• Increased red blood cell count or haemoglobin levels

Contact your doctor if these effects persist, worsen or become troublesome. Regular monitoring may be required to detect changes in blood counts, blood pressure and prostate health.

Serious side effects

Seek prompt medical attention if you experience any of the following:

• Blood clots: Pain, swelling, warmth or redness in one leg, or sudden shortness of breath, may indicate a blood clot.

• Significant fluid retention: New or worsening swelling of the ankles or legs requires medical assessment, particularly if you have heart, kidney or liver disease.

• Worsening urinary symptoms: Difficulty passing urine or a significant change in urinary habits should be reported to your doctor.

• Prolonged or painful erections: Erections that persist for an unusually long time or cause pain require urgent medical attention.

• Unintentional testosterone exposure: Women or children who develop unusual hair growth, acne, changes in genital development or other hormonal changes following contact with the gel should receive medical advice promptly.

• Use Cernos Gel only when prescribed for confirmed testosterone deficiency.

• Apply as directed, wash your hands afterwards and cover the area once dry.

• Prevent contact between the treated skin and women or children.

• Avoid flames and smoking until the gel has dried completely.

• Attend recommended blood tests and report any unusual swelling, high blood pressure or urinary difficulties.

• Inform your doctor about existing health conditions and all medicines you take, especially insulin, anticoagulants and corticosteroids.