Cipenmet 2.5gm Injection

• Complicated urinary tract infections (cUTIs), including pyelonephritis, in adults.
• Hospital-acquired pneumonia (HAP), including ventilator-associated pneumonia (VAP).
• Bacteraemia associated with, or suspected to be associated with, cUTIs or HAP.

This medicine works by stopping the growth of harmful bacteria that cause serious infections. It has two key parts working together. One part attacks the bacteria directly and prevents them from building their protective walls, which are essential for their survival. The other part helps the first one work better by blocking the defense tools some bacteria use to fight off treatment.

Together, they make a strong team that kills even those bacteria that have become hard to treat with regular antibiotics. This helps clear up infections in the urinary tract, lungs, and blood. It's especially useful in hospitals where infections can be more severe and resistant to standard treatments. This medicine is given by a doctor, usually through a drip, and is carefully dosed to suit each patient’s condition.

Before starting treatment, it is important to tell your doctor about all medicines you are taking, including over-the-counter drugs, supplements, and herbal products. This helps prevent serious drug interactions that could reduce the effectiveness of treatment or increase the risk of harmful side effects.

Use of Cipenmet 2.5gm Injection is not recommended in individuals with a history of severe allergic reactions (e.g., anaphylaxis) to cephalosporins, penicillins, or other beta-lactam antibiotics. Serious hypersensitivity reactions may occur, which can be life-threatening. Patients with kidney problems should use this medicine with caution, as it may require dose adjustments to avoid toxicity.

Serious drug interactions may occur with the following:

• Diuretics (e.g., furosemide): May increase the risk of kidney toxicity.
• Aminoglycoside antibiotics (e.g., gentamicin): Co-administration may heighten the risk of nephrotoxicity and should be closely monitored.
• Anticoagulants (e.g., warfarin): May affect blood clotting levels and increase bleeding risk.
• Valproic acid: May lower blood levels of valproic acid, potentially reducing seizure control.

• Store in a refrigerator (2°C – 8°C). Do not freeze. Protect from light.
• Once reconstituted and diluted, use immediately or within the recommended time as per the label.
• If a dose is missed, contact your healthcare provider. Do not double up to make up for a missed dose.
• In case of an overdose, seek emergency medical attention. Symptoms may include confusion, tremors, or seizures.
• Only to be used under medical supervision in a hospital setting.
• Keep out of reach of children.
• Do not use after the expiry date printed on the pack.
• For more details, refer to the official FDA or eMC label.

Cipenmet 2.5gm Injection is available as an intravenous injection and is administered by a healthcare professional in a hospital setting. The recommended dose for adults is 2g/0.5g every 8 hours, infused over 2 hours. It is not taken with food and should never be self-administered. Dosage may vary based on kidney function and severity of infection. Always follow the doctor’s instructions closely.

Like all medicines, Cipenmet 2.5gm Injection may cause side effects, though not everyone gets them. Most are mild and manageable, but some may need medical attention.

Common Side Effects:

• Nausea or vomiting
• Diarrhea
• Headache
• Rash or itching
• Redness or pain at the injection site
• Increased liver enzymes (usually mild and temporary)

Serious Side Effects (Seek medical help immediately):

• Severe allergic reactions (e.g., swelling of face, lips, or throat; difficulty breathing)
• Seizures or confusion, especially in patients with kidney problems
• Clostridium difficile-associated diarrhea (persistent or severe)
• Low white blood cell count (may increase risk of infections)
• Kidney problems (changes in urine output or swelling)

It’s important to inform your healthcare provider if you have any existing kidney or liver conditions, as the dosage may need to be adjusted. Staying hydrated during treatment can help prevent kidney issues. Be sure to tell your doctor about all other medications, including over-the-counter drugs and supplements, to avoid potential interactions. This medicine should only be administered by a healthcare professional, so do not attempt to self-administer. If you experience any unusual symptoms, such as severe stomach pain, persistent diarrhea, or signs of an allergic reaction, seek immediate medical attention. Additionally, avoid alcohol during treatment to reduce the risk of side effects. Always follow your doctor’s instructions carefully for safe and effective use.