CISBLOK 10MG INJECTION

Introduction:

Cisblok 10mg Injection is a nondepolarized neuromuscular blocker consisting of the active substance Cisatracurium. It is used to relax the muscles during surgical procedures, intensive care and to insert a tube into the wind pipe for ventilation. Cisblok 10mg Injection is a neuromuscular blocking agent that improves oxygen supply in critically ill patients. 

Inform your physician before taking this medicine if you have previously experienced bad reactions to anaesthetics. Consult your physician for advice before taking this medicine if you have muscle weakness, tiredness, difficulty coordinating your movements, muscle disorders, burns, paralysis. Report to your physician right away if you experience chest pain, tightness, wheezing, swelling of the face, lips or eyelids after taking this injection.

Uses of Cisblok 10mg Injection:

• To relax muscles during surgeries and intensive care
• To facilitate tube insertion into the windpipe

How Cisblok 10mg Injection works:

Cisblok 10mg Injection inhibits the n-acetylcholine receptors present at the junction of nerve and muscle. This mechanism helps keep the muscle relaxed for a long time during surgeries and provides mechanical ventilation. This injection also helps minimize ventilator-induced lung injuries and inflammation.

Interaction with other drugs:

Inform your physician regarding any medicines you are taking or have taken before the treatment.

More Information:

Store between 2°C and 8°C. Protect from light. Do not freeze.

References:

1. Mylan, Electronic Medicines Compendium (EMC), [Revised on Jul 2021] [Accessed on 25th Aug 2021], https://www.medicines.org.uk/emc/files/pil.2595.pdf 
2. Fresenius Kabi, [Revised on Jul 2016] [Accessed on 25th Aug 2021], http://editor.fresenius-kabi.us/PIs/US-PH-Cisatracurium-Besylate-Inj-FK-451248D-07-2016-PI.pdf 
3. Marieke Kruidering-Hall, Lundy Campbell, Skeletal Muscle Relaxants, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 474-491.
4. Ho et al., Neuromuscular blockade in acute respiratory distress syndrome: a systematic review and meta-analysis of randomized controlled trials, Journal of Intensive Care, 2020, 8:12, https://jintensivecare.biomedcentral.com/track/pdf/10.1186/s40560-020-0431-z.pdf 

How to use Cisblok 10mg Injection:

This injection should be administered only under general anaesthesia, into the vein under the supervision of a qualified anaesthetist.

Safety Advice:

Pregnancy:

Inform your physician before taking this medicine if you are pregnant or think you might be pregnant. 

Breastfeeding: 

Consult your physician for advice before taking this medicine if you are a breastfeeding mother.

Liver:

Inform your physician before taking this medicine if you have liver problems. 

Kidney:

Inform your physician before taking this medicine if you have kidney problems. 

Driving: 

Avoid driving or using machines without your physician’s approval.

Others:

• Inform your physician before taking this medicine if you have previously experienced bad reactions to anaesthetics.
• Consult your physician for advice before taking this medicine if you have muscle weakness, tiredness, difficulty coordinating your movements, muscle disorders, burns, paralysis.
• Inform your physician before taking this medicine if you are sensitive to cisatracurium or any other muscle relaxant.

Side effects are unwanted symptoms caused by medicines. Even though all medications cause side effects, not everyone gets them.

Serious:

• Allergic reactions
• Wheezing
• Chest pain
• Chest tightness
• Lumpy skin rash
• Collapse and shock

Common:

• Low heart rate
• Low BP
• Flushing