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Combiklas Peri Injection

Prescription Required

Salt Composition : Dextrose Solution,amino Acid,intralipid

Manufacturer : ALNICHE LIFE SCIENCES PVT LTD

Origin of Medicine : India

MRP: ₹2860
Price : ₹2374
You Save : ₹486 (17%)

1 Bottle Of 384ml

Pincode
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Introduction to Combiklas Peri Injection

Combiklas Peri Injection contains an active component called Dextrose solution, Amino acids and Intralipid. It is a parenteral nutrition (PN) medication that provides nutritional support to patients who cannot receive oral nutrition. PN is necessary for patients who have a malfunctioning gastrointestinal tract, such as those with burns, trauma, sepsis, short gut syndrome, inflammatory bowel disease, tumors, or pancreatitis. It can also be used to provide additional nutrition before, during, and after surgery. This medication provides nutritional support to patients who cannot receive oral nutrition due to gastrointestinal tract disorders like short gut syndrome, inflammatory bowel disease, tumors, pancreatitis, peritonitis, fistula, and ulcerative colitis. It is also used in critical illnesses like burns, trauma, sepsis, head injuries, and cachexia. 

Patients with hypersensitivity to Dextrose solution + Amino acids + Intralipid or any of the ingredients in the medication should avoid it. This medication should not be used in uncorrected metabolic or electrolyte imbalances, acute liver and kidney failure, or active infection. Patients with severe fluid overload should also avoid using this medication. It should be used cautiously in older adults, as they are more likely to experience side effects such as infection, blood clots, and liver problems.  Combiklas Peri Injection is not approved for use in children under 18.

Uses of Combiklas Peri Injection

Combiklas Peri Injection  is used in the following:

  • Gastrointestinal tract disorders
  • Critical illness
  • Cancer
  • Preoperative, perioperative, and postoperative support
  • Additional nutrition for enteral nutrition patients

Therapeutic Effects of Combiklas Peri Injection

Combiklas Peri Injection  is absorbed into the bloodstream through the vein where it is administered. The dextrose provides energy, the amino acids build and repair tissues, and the lipids provide essential fatty acids.

Interaction of Combiklas Peri Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact withCombiklas Peri Injection, reducing effectiveness by causing undesirable side effects. 

More Information about Combiklas Peri Injection

  • Store at room temperature, between 15-25°C
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Combiklas Peri Injection

Combiklas Peri Injection is administered intravenously, infusing it into a vein. It is typically administered through a central venous catheter (CVC). The choice of administration route may depend on the situation providing the medication.

Safety Advices for Combiklas Peri Injection

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Pregnancy

  

There is not enough reliable information to know if Combiklas Peri Injection is safe to take during pregnancy or breastfeeding. Therefore, you must talk to your doctor before taking this medication if you are pregnant. 

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Breast Feeding

  

Combiklas Peri Injection should only be used during breastfeeding if the potential benefits outweigh the potential risks. Always consult a healthcare provider before taking this medication while breastfeeding.

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Lungs

  

Combiklas Peri Injection has not been specifically studied in patients with lung disease. However, you must consult your healthcare provider before taking this medication if you have lung disease.

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Liver

  

If you have liver disease, you should talk to your doctor before taking Combiklas Peri Injection.

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Alcohol

  

Alcohol can interact with Combiklas Peri Injection and increase the risk of side effects such as liver problems and fluid overload. It is not safe to use this medication with alcohol.

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Driving

  

Combiklas Peri Injection can cause side effects such as drowsiness and fatigue. It is not safe to take this medication while driving.

Side Effects of Combiklas Peri Injection

Combiklas Peri Injection   causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Allergic reactions
  • Blood clots
  • Fluid overload
  • Liver problems
  • Kidney problems
  • Sepsis

Common:

  • Fatigue
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Irritation at the infusion site
  • Increased blood sugar levels
  • Low blood potassium levels
  • Low blood calcium levels
  • Low blood magnesium levels

Word of Advice

Combiklas Peri Injection can cause blood sugar levels to rise, so it is important to monitor your blood sugar levels closely while taking this medication. It can put extra strain on the heart, so monitoring your heart function closely while taking this medication is important. If you have a severe allergic reaction to any of the ingredients in this medication, you should seek immediate medical attention. This medication can worsen metabolic or electrolyte imbalances, so it is important to have these imbalances corrected.  It is important to avoid this medication if you have severe fluid overload.

FAQs

Q 1. What should I do if I experience side effects from Combiklas Peri Injection?

If you experience any side effects from Combiklas Peri Injection, be sure to talk to your doctor. They may need to adjust your dosage or stop your treatment.

Q 2. What should I do if I miss a dose of Combiklas Peri Injection ?

If you miss a dose of Combiklas Peri Injection, contact your doctor or pharmacist for instructions.

Q 3. How long does Combiklas Peri Injection ?

Combiklas Peri Injection is a parenteral nutrition (PN) medication, which means it is administered intravenously. It is metabolized and excreted by the body within a few days. However, the exact amount of time that it stays in the system will vary depending on the individual patient's metabolism and other factors.

Q 4. Can I take Combiklas Peri Injection at home?

Combiklas Peri Injection is typically administered in hospitals or other healthcare settings. However, it is possible to administer this medication at home if you have the necessary training and equipment. If you are considering taking this medication at home, be sure to talk to your doctor first. They can help you determine if it is safe for you to do so and provide you with the necessary instructions.

Q 5. How much Combiklas Peri Injection will I need?

The amount of Combiklas Peri Injection you need will depend on your needs, such as weight, height, and medical condition. Your doctor will determine the correct dosage for you.

Q 6. How often will I need to receive Combiklas Peri Injection ?

You will typically need to receive Combiklas Peri Injection once a day. However, depending on your needs, your doctor may need to adjust the dosing schedule.

Fact Box of Combiklas Peri Injection

Molecule name: Dextrose solution, Amino acids, Intralipid

Therapeutic class:  Nutritional support

Pharmacological class: Parenteral nutrition (PN)

 

Indications: 

1. Gastrointestinal tract disorders

2. Critical illness

3. Cancer

4. Preoperative, perioperative, and postoperative support

5. Additional nutrition for enteral nutrition patients

 

References

  1. Alniche Life Sciences Pvt. Ltd., [Revised on 2021][Accessed on 28th September 2023], https://www.alniche.com/product/combiklas/
  2. Baxter Healthcare Corporation, US Food and Drug Administration, [Revised on  May 2022] [Accessed on 28th September 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/017643s072,018449s039lbl.pdf
  3. Corey Resnick, Nutritional Protocol for the Treatment of Intestinal Permeability Defects and Related Conditions, Natural Medicine Journal, 2010, 2(3), https://www.naturalmedicinejournal.com/print/61
  4. Jeffery W. Spray, Review of Intravenous Lipid Emulsion Therapy, Journal of Infusion Nursing, 2016, 39(6), https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102272/pdf/jinfn-39-377.pdf 

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