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Dapaglyn L 10mg/5mg Tablet
Last updated on 03 Oct 2026 | 08:56 AM (IST)
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Introduction
Dapaglyn L 10mg/5mg Tablet is a combination medicine used to manage type 2 diabetes in adults. It helps to lower blood sugar levels when diet and exercise alone are not enough. This medicine is usually prescribed when single-drug therapy doesn’t give the desired results, especially in patients who need better control of their fasting and post-meal blood sugar.
This combination works in different ways to improve blood sugar levels and can also support weight control and reduce the risk of diabetes-related complications when used properly. However, it is not meant for type 1 diabetes or diabetic ketoacidosis.
Your doctor will decide the right dose for you based on your health condition and other medications you may be taking. Always follow their advice and do not stop or change the dose without consulting them.
Uses
Dapaglyn L 10mg/5mg Tablet is used together to manage blood sugar levels in adults with type 2 diabetes. Dapagliflozin helps the kidneys remove excess glucose, while Linagliptin increases insulin production and reduces glucose production.
How Dapaglyn L 10mg/5mg Tablet Works
This Dapaglyn L tablet works in two ways:
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Dapagliflozin helps remove extra sugar from the body through urine.
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Linagliptin increases insulin release after meals and reduces sugar production by the liver.
Together, they help control both fasting and post-meal sugar levels.
Interaction of Dapaglyn L 10mg/5mg Tablet with Other Drugs
Always inform your doctor about any medications you are taking, including:
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Other diabetes medicines like insulin or sulfonylureas (they may cause low blood sugar).
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Diuretics (water pills) as they may increase the risk of dehydration.
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Blood pressure medicines (like ACE inhibitors).
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Medicines that affect kidney function.
These drugs may increase side effects or affect how Dapaglyn L 10mg/5mg Tablet works.
Storage Conditions
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Store in a cool, dry place below 30°C.
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Keep away from direct sunlight and moisture.
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Keep out of reach of children.
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Do not use the medicine after the expiry date.
Safety Advices
Pregnancy
There is limited information about the use of Dapaglyn L 10mg/5mg Tablet in pregnancy. Your doctor will decide if it is safe for you.
Breast Feeding
It is not known whether this medicine passes into breast milk. Consult your doctor before using it during breastfeeding.
Liver
People with liver problems should use this medicine carefully. Inform your doctor about any liver disease you have.
Alcohol
Drinking alcohol may affect your blood sugar levels and increase the risk of side effects. Avoid or limit alcohol while taking this medicine.
Driving
Low blood sugar may affect your ability to drive or operate machines. Check how you feel before driving.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.
Common side effects
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Urinary tract infections
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Increased urination
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Nasopharyngitis (cold symptoms)
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Headache
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Back pain
Serious side effects
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Diabetic ketoacidosis
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Severe allergic reactions (rash, swelling, difficulty breathing)
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Kidney problems (decreased kidney function)
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Low blood pressure (dizziness, fainting)
Expert Tips
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Take the tablet at the same time daily to help build a routine.
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Drink enough fluids to stay hydrated, especially in hot weather or while exercising.
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Follow a balanced diet and regular exercise to get the best reults.
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Keep a sugar source handy to treat sudden low blood sugar.
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Don’t skip meals, and monitor your sugar levels often.
FAQs
Q1.
What is Dapaglyn L 10mg/5mg Tablet used for?
Dapaglyn L 10mg/5mg Tablet are used to manage blood sugar levels in adults with type 2 diabetes. Linagliptin helps increase insulin production, while Dapagliflozin reduces glucose reabsorption in the kidneys.
Q2.
Is the Dapagliflozin and Linagliptin combination safe for kidneys?
The Dapagliflozin and Linagliptin combination can be safe for kidneys when used in patients with normal or mildly impaired kidney function. However, it should be used with caution in those with moderate to severe kidney impairment. Regular monitoring of kidney function is recommended during treatment.
Q3.
Does the Dapagliflozin and Linagliptin combination reduce HbA1c?
Yes, the Dapagliflozin and Linagliptin combination effectively reduces HbA1c levels. Dapagliflozin helps lower blood sugar by increasing glucose excretion, while Linagliptin enhances insulin secretion, together improving long-term blood sugar control in people with type 2 diabetes.
Q4.
What to avoid when taking Dapaglyn L 10mg/5mg Tablet?
Avoid dehydration by staying well-hydrated, as excessive urination can occur. Also, avoid using the combination if you have severe kidney problems or a history of pancreatitis.
Q5.
Does the Dapaglyn L 10mg/5mg Tablet increase creatinine?
Dapaglyn L 10mg/5mg Tablet may slightly increase creatinine levels due to its effect on kidney function. Regular monitoring of kidney function is recommended during treatment.
Fact Box
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Molecule Name: |
Dapagliflozin, Linagliptin |
|
Therapeutic Class: |
Antidiabetic |
|
Pharmacological Class: |
SGLT2 inhibitor + DPP-4 inhibitor |
|
Indications: |
Type 2 Diabetes Mellitus |
References
1. Jain A, Vispute A, Dange A, Naskar A, Mondal A, Vivekanand B, Sharma B, Varade D, Shukla D, Bhatia G, Chaudhari H, Ram Babu K, Gavali O, Sorate S, Bhanushali S, Kothari V, Khandelwal V, Sharma A, Pawar R, Mayabhate M, Shahavi V, Rajput A, Jaiswal M. A Randomized, Double-Blind, Parallel-Group Phase III Trial Investigating the Glycemic Efficacy and Safety Profile of Fixed-Dose Combination Dapagliflozin and Linagliptin Over Linagliptin Monotherapy in Patients with Inadequately Controlled Type 2 Diabetes with Metformin. https://pubmed.ncbi.nlm.nih.gov/37957465/
2. Hong JH, Kim MJ, Min KW, Won JC, Kim TN, Lee BW, Kang JG, Kim JH, Park JH, Ku BJ, Lee CB, Kim SY, Shon HS, Lee WJ, Park JY. Efficacy and safety of a fixed-dose combination of dapagliflozin and linagliptin (AJU-A51) in patients with type 2 diabetes mellitus: A multicentre, randomized, double-blind, parallel-group, placebo-controlled phase III study. https://pubmed.ncbi.nlm.nih.gov/39375869/
3. Dharmalingam M, Kumar Sharma S, Prakash V, Maiti A, Kumar R, Murthy LSS, Ramanathan B, Maheshwari S, Naik Kethavath S, Ogale D, Bachubhai PVK, Sonawane AB, Shah V, Suresh M, Chakraborty S, Kumar Manjunath K. Evaluating the Efficacy, Safety, and Tolerability of Combination Therapy of Dapagliflozin and Linagliptin Over Dapagliflozin and Vildagliptin in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 03 Oct 2026 | 08:56 AM (IST)

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