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Dapaglyn M 500mg Tablet

Prescription Required

Salt Composition : Dapagliflozin,metformin

Manufacturer : ZYDUS CADILA

Origin of Medicine : India

MRP: 134.89
Price :115
You Save :20 (15%)

15 Tablet(s) In A Strip

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Introduction to Dapaglyn M 500mg Tablet

Dapaglyn M 500mg tablet contains the active ingredient Dapagliflozin + Metformin. It is an anti-diabetic drug. Dapagliflozin belongs to the group of medications called sodium-glucose co-transporter. Metformin belongs to the class of medications called biguanides. It is used to treat type 2 diabetes mellitus in patients aged 18 years and older. This combination of medicines is taken by mouth (orally). 

Dapaglyn M 500mg tablet is always taken in combination with diet and exercise. Your doctor may prescribe this medicine with other anti-diabetic medications when your blood sugar is high and uncontrolled. Do not take this medicine if you are allergic to Dapagliflozin, Metformin, or any of the other ingredients of this medicine. Do not take this tablet if you have ever had a diabetic coma, severely reduced kidney function, severe infection, or liver problems. Inform your doctor immediately if you have vomiting, stomach ache, muscle cramps, severe tiredness, difficulty in breathing, reduced body temperature, and heartbeat after taking this medicine.  

Inform your physician if you get urinary tract infections because this medicine may cause UTI. This medicine is not recommended for children and adolescents under 18 years of age. Your doctor will check for kidney function at least once every year or more frequently while you are taking this medicine. The common side effects of this medicine are diarrhea, nausea, vomiting, urinary tract infections, and headache.


Uses of Dapaglyn M 500mg Tablet

  • To treat type 2 diabetes mellitus

Therapeutic Effects of Dapaglyn M 500mg Tablet

Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess sugar from your body via your urine and lowering the sugar in your blood. Metformin primarily decreases hepatic glucose production and decreases intestinal absorption of glucose. It works mainly by inhibiting glucose production in the liver.  


Interaction of Dapaglyn M 500mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Dapaglyn M 500mg tablet and reduce its effectiveness by causing undesirable side effects. 


More Information about Dapaglyn M 500mg Tablet

  • Store at 20°C to 25°C
  • Protect the medicine from light and excessive moisture.
  • Keep the medicine out of reach of children and pets
  • If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

How to consume Dapaglyn M 500mg Tablet

It is an orally available prescription drug. Your doctor will decide the dose and duration of Dapaglyn M 500mg tablet based on the blood sugar and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time with food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. 


Safety Advices for Dapaglyn M 500mg Tablet

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Pregnancy

  

Do not take Dapaglyn M 500mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment.

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Dapaglyn M 500mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. 

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Lungs

  

It is unknown whether Dapaglyn M 500mg tablet is safe to be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy. 

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Liver

  

Dapaglyn M 500mg tablet should be cautiously administered if you have liver problems. Dose adjustments are necessary for severe liver failure. Inform your physician if you have any liver diseases before initiating the treatment. 

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Alcohol

  

It is unsafe to consume alcohol with Dapaglyn M 500mg tablet. Inform your doctor about your drinking habits. 

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Driving

  

Dapaglyn M 500mg tablet may cause dizziness and drowsiness. Driving or operating heavy machinery is unsafe if you experience any symptoms that affect your ability to concentrate and react. Inform your physician if you face any of these symptoms.


Side Effects of Dapaglyn M 500mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Common 

  • Nausea, vomiting
  • Back pain
  • Urinary tract infection
  • Diarrhea
  • Stomach ache, loss of appetite
  • Dizziness
  • Rash

Serious  

  • Decreased vitamin B12
  • Low blood sugar level
  • Unusual sleepiness or tiredness
  • Rapid weight loss

Word of Advice

To control your diabetes, you still need to keep to diet and exercise, even when you are taking this medicine. So it is important to keep following the advice about diet and exercise from your doctor. Avoid excessive alcohol while taking this medicine. If you take more tablets than you should, you may experience lactic acidosis. Symptoms of lactic acidosis include feeling or being very sick, vomiting, stomach ache, muscular cramps, severe tiredness or difficulty breathing. If you face any of these symptoms, stop taking this medicine immediately and contact a doctor or the nearest hospital.


FAQs

Q 1. Can you take Dapaglyn M 500mg tablet twice a day?

Your doctor will decide the dose, strength, and frequency of the medicine based on your blood sugar levels and other factors. Take the tablet as prescribed by your doctor.

Q 2. How does Dapaglyn M 500mg tablet work?

Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess sugar from your body via your urine and lowering the sugar in your blood. Metformin primarily decreases hepatic glucose production and decreases intestinal absorption of glucose. It works mainly by inhibiting glucose production in the liver.

Q 3. What is Dapaglyn M 500mg tablet used for?

Dapaglyn M 500mg tablet is used to treat type 2 diabetes mellitus in adults aged 18 years and older.

Q 4. Can Dapagliflozin and Metformin cause weight loss?

Both Dapagliflozin and Metformin can potentially contribute to weight loss in individuals with type 2 diabetes. Dapagliflozin can lead to a mild reduction in body weight by increasing urinary glucose excretion, while Metformin may help with modest weight loss by reducing appetite and improving insulin sensitivity.

Q 5. How long does it take for Dapagliflozin and Metformin to show its effects?

The effects of Dapagliflozin and Metformin may vary from person to person. It may take several days to weeks to observe significant improvements in blood sugar control. It is important to continue taking the medication as prescribed and attend regular follow-up appointments with your healthcare provider.


Fact Box of Dapaglyn M 500mg Tablet

Molecule name: Dapagliflozin + Metformin

Therapeutic class:  Antidiabetic

Pharmacological class: 

1. Dapagliflozin - SGLT2 inhibitor 

2. Metformin - Biguanides 

Indications: Type 2 diabetes mellitus


References

  1. Xigduo 5 mg/850 mg film coated tablets - Patient Information Leaflet (PIL) - (emc). www.medicines.org.uk. [Revised 30 Nov]  [cited 2023 Jun 5]. Available from: https://www.medicines.org.uk/emc/product/5293/pil
  2. AstraZeneca Pharmaceuticals - Xigduo 5 mg/850 mg film coated tablets. Access.fda.gov. [Revised 2017 Jul] [cited 2023 Jun 5]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Insulin, oral hypoglycaemic drugs and glucagon, 7th edition, 2013, 278.
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Endocrine pancreas and pharmacotherapy of diabetes mellitus and hypoglycaemia, 12th edition, 2011, 1258-1259.

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