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Darbenef 40mcg Injection
Last updated on 19 Aug 2026 | 06:50 AM (IST)
₹1147
MRP: ₹3276.56
(You Save ₹2129.56)
1 PREFILLED SYRINGE(s)
Darbenef 40mcg Injection
Salt Composition
DARBEPOETIN ALFAMarketer
MERYNOVA LIFE SCIENCES INDIA PRIVATE LIMITED
Prepaid Only. Non-Returnable.
65% OFF
₹1147
MRP: ₹3,276.56
Inclusive of all taxes
65% Off
Salt Composition
DARBEPOETIN ALFAMarketer
MERYNOVA LIFE SCIENCES INDIA PRIVATE LIMITED
Prepaid Only. Non-Returnable.
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Introduction
Darbenef 40mcg Injection contains the active ingredient Darbepoetin Alfa. It is an antineoplastic drug that belongs to the class of medications called hematopoietic growth factors. It is used to treat anemia (lower than normal RBC) in people with chronic kidney disease. It is also indicated to treat anemia caused by chemotherapy in people with certain types of cancer. The symptoms of anemia are fatigue, weakness, and shortness of breath.
Do not take Zynesp 25mcg injection if you are allergic to Darbepoetin alfa or any other ingredients and have uncontrolled blood pressure. Inform your physician if you have high blood pressure, anemia, a history of seizures, epilepsy, liver disease, or allergy to latex or hepatitis C. Inform your physician if you are pregnant or breastfeeding.
If you have severe headache, dizziness, drowsiness, confusion, problems with your eyesight, nausea, vomiting, or seizures after taking Zynesp 25mcg injection, inform your physician immediately and seek medical advice. This medicine's most common side effects are hypertension, shortness of breath, swelling in the legs, and cough. Darbenef 40mcg Injection price varies by retailer and location.
Uses
Darbenef 40mcg Injection uses are:
To treat anemia in chronic kidney failure
To treat anemia caused by chemotherapy
How Darbenef 40mcg Injection Works
Darbenef 40mcg Injection is an erythropoiesis-stimulating protein produced by recombinant DNA technology. It is closely related to erythropoietin and stimulates erythropoiesis by the same mechanism, and both agents bind to progenitor stem cells stimulating the production/differentiation of red blood cells. It works by causing the bone marrow to make more red blood cells.
Interaction of Darbenef 40mcg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Darbenef 40mcg Injection and reduce its effectiveness by causing undesirable side effects.
Storage Conditions
Store in a refrigerator (2°C to 8°C).
Do not freeze. Store in the original package to protect from light.
Keep the injection away from the reach of children and pets.
If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to use Darbenef 40mcg Injection
This injection is to be given under the skin (subcutaneous). Your doctor, nurse, or other healthcare professional will train you on how to inject yourself with this pre-filled pen. Do not attempt to inject the pre-filled pen unless you are well-trained. Never inject the medicine into your vein. If you need help to inject the medicine, visit the nearby hospital or clinic. Your healthcare provider will decide the Darbenef 40mcg Injection dosage.
Safety advice
Pregnancy
There are no adequate and well-controlled studies on the use of Darbenef 40mcg Injection in pregnant women. Inform your physician if you are pregnant, suspecting, or planning for pregnancy during the treatment.
Breast Feeding
Breastfeeding is not recommended in patients taking Darbenef 40mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Zynesp 25mcg epoetin injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Darbenef 40mcg Injection is unsafe to administer in patients with liver problems. Dose adjustments are necessary. Inform your physician if you have any liver diseases or problems before initiating the therapy.
Alcohol
It is unknown whether consuming alcohol is safe during the treatment with Darbenef 40mcg Injection. Inform your doctor if you are a chronic drinker.
Driving
Darbenef 40mcg Injection will not make you feel tired, dizzy, or sleepy. It is safe to drive or operate heavy machinery after taking this medicine.
Side Effects
Darbenef 40mcg Injection side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Swelling in the face and body
Low blood pressure
Abdominal pain
Shortness of breath
cough
Serious
Heart problems
Severe skin reactions
Anemia
Seizure attack
Lung problems
Expert Tips
Your doctor will determine the exact dose and frequency of your injection.
This medicine is administered as a shot under the skin by a nurse or healthcare professional.
You may be trained to give the injection at home—ensure you fully understand the instructions before self-administration.
Do not use more medicine or take it more frequently than prescribed.
Do not shake the vial or syringe before use.
You will be guided on the appropriate body areas for injection; rotate the injection site each time to avoid irritation.
Keep a record of where each shot is given to ensure proper rotation.
FAQs
Q1.
Can Darbenef 40mcg Injection be used in patients with kidney failure who are undergoing dialysis?
Yes, Darbenef 40mcg Injection is commonly used in patients with kidney failure who are undergoing dialysis to manage anemia.
Q2.
Can Darbenef 40mcg Injection be used in patients with a history of heart disease?
Darbenef 40mcg Injection should be used with caution in patients with a history of heart disease, as it may increase the risk of certain cardiovascular events. It is crucial to discuss the potential risks and benefits with a healthcare provider before initiating treatment.
Q3.
Can Darbenef 40mcg Injection be used to treat anemia caused by nutritional deficiencies?
Darbenef 40mcg Injection is not typically used to treat anemia caused by nutritional deficiencies. It is primarily used for anemia related to chronic kidney disease, cancer chemotherapy, and other specific conditions. Nutritional deficiencies require appropriate dietary changes and/or supplementation.
Q4.
Can Darbenef 40mcg Injection be used to treat anemia in patients undergoing radiation therapy?
Darbenef 40mcg Injection is used to treat anemia in patients undergoing chemotherapy, depending on the specific circumstances and the healthcare provider's recommendation. The anemia is typically managed through a comprehensive treatment plan determined by the oncology team.
Q5.
Can Darbenef 40mcg Injection interact with other medications?
Darbenef 40mcg Injection may interact with certain medications, such as blood thinners or immunosuppressants. It is important to inform the healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions or adverse effects.
Fact Box
Molecule name | Darbepoetin Alfa |
Therapeutic class | Antineoplastics |
Pharmacological class | Hematopoietic growth Factors |
Indications | 1. To treat anemia in chronic kidney failure 2. To treat anemia caused by chemotherapy |
References
Aranesp solution for injection in pre-filled pen (SureClick) - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk. Published March 2022. Accessed May 10, 2023. http://www.medicines.org.uk/emc/product/6958/smpc
Darbepoetin Alfa.; Revised June 2011. Accessed May 10, 2023. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103951orig1s5173_103951orig1s5258lbl.pdf
Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Hematopoietic agents, 12th edition, 1071 - 1072.
KD Tripathi, Essentials of Medical Pharmacology, Haematinics and Erythropoietin, 7th edition, 2013, 611.
Disclaimer
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 19 Aug 2026 | 06:50 AM (IST)
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