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Dashori 100mg Tablet

Prescription Required

Salt Composition : Dasatinib

Manufacturer : TORRENT PHARMACEUTICALS LTD

Origin of Medicine : India

MRP: 8100
Price : 4860
You Save : 3240 (40%)

30 Tablet(s) In A Bottle

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Introduction to Dashori 100mg Tablet

Dashori 100mg Tablet consists of the active ingredient Dasatinib. It is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia. This medicine is used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukaemia (CML) in the chronic phase and Ph+ acute lymphoblastic leukaemia in patients resistant to other therapies. 

Chronic Myeloid Leukemia refers to a type of blood cancer that makes the body produce too many white blood cells that happen due to alteration in the Philadelphia chromosome. Acute Lymphoblastic Leukemia is the most common form of blood cancer that affects children. In this case, the lymphocytes of white blood cells multiply too quickly and live too long.

The common side effects that are likely to be associated with Dashori 100mg Tablet are diarrhoea, headache, cough, rash, nausea, tiredness, vomiting, muscle pain, weakness, low appetite, and high or low blood pressure. Inform your doctor if these side effects disturb or persist in you.

Inform your doctor if you are allergic to Dasatinib and its ingredients. Before starting treatment with this medication, you should let your physician know if you have liver or heart problems, breathing difficulties, chest pain, cough, hepatitis B infection, or bleeding problems. 

This medicine could cause a severe reduction in the number of platelets, WBC or RBC in the blood. Ensure that your physician monitors your blood levels at regular intervals. Tell your healthcare professional about all the medicines you take, including prescription and over-the-counter medicines, vitamins, antacids, and herbal supplements. It is not recommended for children below one year of age. 


Uses of Dashori 100mg Tablet

Dashori 100mg Tablet is indicated for the following conditions:

  • Children and adults with chronic myeloid leukaemia.
  • Adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia (Ph+ ALL) with resistance to prior therapy.

Therapeutic Effects of Dashori 100mg Tablet

Dashori 100mg Tablet works by preventing the abnormal protein from signalling the growth of cancer cells. This aids in preventing or reducing the spread of cancer cells.


Interaction of Dashori 100mg Tablet with other drugs

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Dashori 100mg Tablet and can cause undesirable side effects. 


More Information about Dashori 100mg Tablet

  • Store protected from light at a temperature not exceeding 30c.

How to consume Dashori 100mg Tablet

Take the tablet with or without food at the same time each day.


Safety Advices for Dashori 100mg Tablet

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Pregnancy

  

Dashori 100mg Tablet is not recommended for use during pregnancy unless clearly necessary. Your physician will discuss the potential risks during pregnancy. Women should use effective birth control during treatment and 30 days after the final dose.

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Breast Feeding

  

It is not recommended to breastfeed while taking Dashori 100mg Tablet as it is not known whether this medication passes into breast milk. You should not breastfeed during treatment and for 2 weeks after your final dose.

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Lungs

  

It is unknown whether Dashori 100mg Tablet is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment.

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Liver

  

Inform your physician before starting this treatment if you have liver disease.

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Alcohol

  

It is not known whether it is safe to consume alcohol with Dashori 100mg Tablet. Consult your doctor for advice.

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Driving

  

It is not known whether it is safe to drive while in treatment with Dashori 100mg Tablet. Consult your doctor for advice.


Side Effects of Dashori 100mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious side effects of Dashori 100mg Tablet are:

  • Unusual bleeding or bruising
  • Rapid heart rate
  • Changes in consciousness or speech
  • Breathlessness and swelling all over the body
  • Fever or signs of infection
  • Fluid retention
  • Heart problems
  • Myelosuppression
  • Severe allergic reaction

Common side effects of Dashori 100mg Tablet are:

  • Diarrhea
  • Headache
  • Cough
  • Rash
  • Nausea, tiredness, vomiting
  • Muscle pain, weakness
  • Low appetite
  • High or low BP

Word of Advice

It is advised to use effective contraceptives for both men and women taking Dashori 100mg Tablet during treatment and 30 days after the last dose. Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice blood in your urine or stools. If you take an antacid medicine, take it 2 hours before or 2 hours after taking Dashori 100mg Tablet. 


FAQs

Q 1. Can children use Dashori 100mg Tablet?

Dashori 100mg Tablet is not recommended for children under the age of one.

Q 2. Who is contraindicated to take Dashori 100mg Tablet?

Dashori 100mg Tablet is contraindicated for pregnant and breastfeeding women and children whose age below one year. It is not recommended if you are allergic to Dashori 100mg Tablet and its ingredients.

Q 3. Should Dashori 100mg Tablet be taken with food?

Yes, Dashori 100mg Tablet can be taken with or without food. Do not take this medication with grape fruit and its juices.

Q 4. Is Dashori 100mg Tablet a chemotherapy drug?

Yes, Dashori 100mg Tablet is a chemotherapy medication that belongs to the group of Tyrosine kinase inhibitors.

Q 5. Can Dashori 100mg Tablet cause hair loss?

Yes, Hair loss is one of the common side effects of taking Dosatinib. Consult your doctor for advice if this side effect disturbs or persists you.


Fact Box of Dashori 100mg Tablet

Molecule Name: DasatinibTherapeutic class: Anti-neoplastics
Pharmacological class: Tyrosine kinase inhibitor

Indications: 

1. Myeloid leukemia 

2. Philadelphia chromosome-positive acute lymphoblastic leukemia 


References

  1. Bristol-Myers Squibb Pharma, Electronic Medicines Compendium (EMC), [Revised on Mar 2022] [Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.7745.pdf
  2. Bristol-Myers Squibb Company, [Revised on Jun 2021] [Accessed on 1st Dec 2022], https://packageinserts.bms.com/ppi/ppi_sprycel.pdf
  3. H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Disclaimer

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