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Depo-Provera Injection
Prescription Required
Salt Composition : Medroxyprogesterone Acetate
Manufacturer : PFIZER LTD
Origin of Medicine : Belgium
1 Prefilled Syringe(s)
Introduction to Depo-provera Injection
Depo-Provera Injection belongs to the class of medications known as progestins, a synthetic form of the female hormone progesterone. It contains the active ingredient Depo-Provera Injection. This medicine is primarily used to treat various menstrual and hormonal disorders, including abnormal uterine bleeding, secondary amenorrhea (absence of menstruation), and endometriosis. It is also used as part of hormone replacement therapy (HRT) in postmenopausal women and for reducing the risk of endometrial hyperplasia. Additionally, it may be prescribed for certain hormone-responsive cancers, including endometrial and breast cancer, and is also used as a long-acting contraceptive in specific forms.
Common side effects of Depo Provera Injection include headache, breast tenderness, bloating, mood changes, nausea, changes in menstrual flow, and weight gain. Notify your healthcare provider if these side effects persist or worsen.
Inform your doctor if you have a history of blood clots, liver disease, unexplained vaginal bleeding, breast cancer, or stroke before starting treatment. This medicine is not recommended during pregnancy and breastfeeding unless advised by your physician. Routine check-ups, including pelvic exams and mammograms, are advised during long-term use. At mrmed.in, we offer a competitive price of Depo Provera injection, ensuring both quality and affordability for our customers.
Uses of Depo-provera Injection
Depo provera injection uses are the following:
- Treatment of abnormal uterine bleeding due to hormonal imbalance
- Management of secondary amenorrhea
- Prevention of endometrial hyperplasia in postmenopausal women receiving estrogen therapy
- Palliative treatment for endometrial or breast cancer
- Management of endometriosis-related pain and lesions
- Long-acting contraceptive (in injectable form)
Therapeutic Effects of Depo-provera Injection
Depo-Provera Injection mimics the natural hormone progesterone, which regulates ovulation and menstruation. It works by modifying the uterine lining, inhibiting ovulation, and altering the hormonal balance to reduce abnormal bleeding. In hormone-responsive cancers, it helps slow tumor growth by suppressing estrogen activity and reducing hormone receptor expression.
Interaction of Depo-provera Injection with other drugs
Inform your doctor of all medications, supplements, or herbal remedies you are currently taking. Certain drugs may reduce the effectiveness or increase side effects of Depo-Provera Injection, such as:
- Rifampin, phenytoin, carbamazepine, and phenobarbital – may reduce hormone levels
- St. John’s Wort – may affect hormone metabolism.
- Corticosteroids or immunosuppressants – may require dose adjustment.
More Information about Depo-provera Injection
- Store at a temperature below 25°C
- Protect from light and moisture.
- Keep out of reach of children.
How to consume Depo-provera Injection
Depo-Provera is given as an intramuscular (IM) injection, usually in the upper arm or buttock, by a healthcare professional every 12 to 13 weeks (about every 3 months). It must be administered within the first 5 days of your menstrual cycle to ensure immediate contraceptive protection. If you're switching from another form of birth control, your doctor will guide you on proper timing. It's important to receive each shot on schedule to maintain its effectiveness in preventing pregnancy.
Safety Advices for Depo-provera Injection
Pregnancy
Depo-Provera Injection is not recommended during pregnancy, especially during the first trimester, due to potential risks to the developing fetus. Inform your doctor immediately if you become pregnant while using this medication.
Breast Feeding
Use caution if breastfeeding. Medroxyprogesterone may pass into breast milk and affect the infant. Consult your doctor before using this medication while nursing.
Lungs
Patients with a history of pulmonary embolism or asthma should consult their physician before use.
Liver
Avoid this medication if you have severe liver impairment or liver tumors. Liver function should be monitored during prolonged use.
Alcohol
There are no direct interactions with alcohol, but it's best to limit consumption as alcohol may worsen mood changes or fatigue associated with the drug.
Driving
Depo-Provera Injection may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how this medicine affects you.
Side Effects of Depo-provera Injection
Common side effects:
- Irregular menstrual periods or spotting
- Headache
- Nausea
- Breast tenderness
- Weight changes
- Mood swings
- Acne or skin issues
Serious side effects (require immediate medical attention):
- Sudden vision changes or eye pain
- Chest pain or shortness of breath
- Severe headache or dizziness
- Swelling in the legs or unexplained pain
- Yellowing of the skin or eyes (possible liver issues)
- Unusual vaginal bleeding
Always report any unusual or persistent symptoms to a healthcare provider.
Word of Advice
Consistency is key with this medication. If you're taking it as a tablet, take it at the same time every day. For those on injections, mark your calendar for follow-ups every 12 weeks. While using this medicine, maintain a healthy diet rich in calcium and vitamin D to support bone strength. Avoid smoking and limit alcohol consumption. Inform all healthcare professionals involved in your care that you're on hormonal therapy, especially before surgeries or medical tests.
FAQs
Q 1. What is Depo-Provera Injection used for?
It is mainly used to treat irregular periods, prevent abnormal uterine bleeding, act as birth control (injection form), and manage symptoms of endometriosis or certain cancers.
Q 2. When is the best time to take the tablet?
The tablet should be taken at the same time each day, usually at bedtime or as directed by your doctor. This helps maintain consistent hormone levels.
Q 3. Should Depo-Provera Injection be taken before or after meals?
It can be taken with or without food, but taking it after meals may help reduce stomach upset in some individuals.
Q 4. How long does it take for the injection to work?
When given within the first 5 days of a menstrual cycle, the injection begins working almost immediately as birth control. Otherwise, use backup contraception for 7 days.
Q 5. Can this medication affect future fertility?
Fertility usually returns after stopping the medicine, but it may take several months, especially after stopping the injection. It’s not permanent.
Fact Box of Depo-provera Injection
Molecule name: Medroxyprogesterone Acetate
| Pharmacological class: Progestins |
Pharmacological class: Progestins | Indications: 1. Abnormal uterine bleeding, 2. Amenorrhea, endometrial hyperplasia prevention, 3. Hormone-responsive cancers, 4. Contraception |
References
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.