DEXAM 4MG TABLET

Introduction:

Dexam 4mg Tablet consists of the active ingredient Dexamethasone. It is indicated to prevent nausea and vomiting in patients receiving chemotherapy. It is also used to manage various disorders of the immune system and reduces inflammation. It belongs to a category of drugs called corticosteroids, commonly referred to as steroids. 

Corticosteroids are hormones that are produced naturally by the body to support overall health and wellness. Dexam 4mg Tablet is contraindicated in case of hypersensitivity. Long term use of Dexamethasone can cause endocrine disorders, eye problems, heart problems, increased risk of infections and increased requirement of anti-diabetic drugs in diabetic patients.

Uses of Dexam 4mg Tablet:

• Adjunct to other anti-cancer drugs for treating adults with multiple myeloma
• Treatment of various diseases of the immune system
• Reduction of inflammation

How Dexam 4mg Tablet Works:

Dexam 4mg Tablet acts by reducing the inflammation caused due to disorders in various organs and modifies the immune response of the body. It reduces the cortisol concentration in the blood. The accurate mechanism of action of Dexam 4mg Tablet in multiple myeloma is unknown, however it is believed to induce death of tumor cells.

Interactions with other drugs 

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

Store the tablets at a temperature below 25˚C, away from reach of children. 

References:

1. Aspen Pharma Trading Limited, Electronic Medicines Compendium (EMC), [Revised on Nov 2017] [Accessed on 22nd Apr 2021] https://www.medicines.org.uk/emc/files/pil.5411.pdf 
2. Kenneth R. McQuaid, Drugs Used in the Treatment of Gastrointestinal Diseases, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 1087-1119
3. Dexcel Pharma Technologies Ltd, US Food and Drug Administration,  [Revised on Oct 2019] [Accessed on 22nd Apr 2021] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/211379s000lbl.pdf 

How to use Dexam 4mg Tablet:

Swallow Dexam 4mg Tablet whole with a glass of water. Do not crush or chew the tablets.

Safety advice

Pregnancy:

Inform your physician before beginning treatment with this medicine if you are pregnant or trying to become pregnant.

Breastfeeding: 

Tell your physician before taking this medicine if you are breastfeeding or planning to breastfeed your baby.

Liver: 

Inform your physician before taking this medicine if you have liver problems.

Kidney:

Inform your physician before taking this medicine if you have kidney problems.

Driving:

Avoid driving or doing things that require concentration if you experience any side effects.

Others:

• Inform your physician if you have recently received vaccination. 
• Report to your physician if you experience visual disturbances. 
• Check with your physician if you have fungal infections, Hepatitis B, viral infections, diabetes, cushing’s syndrome, TB, cerebral malaria, high BP, heart disorders, migraine, bone disorders, infections, eye disease, thyroid disorders, muscle weakness, epilepsy or stomach problems.
• Female patients of reproductive potential should use effective contraception method while on treatment with This medicine.
• Inform your physician right away if you have allergic reactions to dexamethasone or its ingredients.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Severe allergic reactions
• Severe infection that makes you ill
• Depression, anxiety and suicidal thoughts
• Blood disorders
• Behavioural and mood disturbances
• Heart failure
• Severe Breathlessness
• Endocrine disorders like increased blood sugar levels

Common:

• Severe thirst
• Frequent urination
• Electrolyte imbalances
• Muscle weakness
• Eye problems
• Swelling of face and body
• Osteoporosis
• Frequent infections
• Irregular or absence of periods in women
• Indigestion
• Pain in the stomach and back
• Skin disorders
• Headache
• High BP