DOCSHIL 120MG INJECTION

Introduction:

Docshil 120mg Injection is a chemotherapy medication containing the active constituent docetaxel. It is used to treat breast cancer, prostate cancer, non-small cell lung cancer, stomach cancer, head and neck cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. This chemotherapy medication is used alone or in combination with other anticancer medicines. 

It is contraindicated in patients with a very low number of white blood cells or severe liver diseases. Use effective birth control during the treatment and for at least 6 months after the last dose. You need to inform your physician if you have kidney problems, heart problems, epilepsy, or alcohol addiction before taking Docshil 120mg Injection.

During treatment, you may be given other medicines to maintain the number of your blood cells. Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with Docshil 120mg Injection.

Uses of Docshil 120mg Injection:

• Non-small cell lung cancer
• Breast cancer
• Stomach cancer
• Prostate cancer
• Head and neck cancer

How Docshil 120mg Injection works:

Docshil 120mg Injection inhibits the microtubule structures present in the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth of cancer cells.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

• Keep Docshil 120mg Injection out of sight and reach of children.
• Store in a refrigerator at 2°C – 8°C.

References:

1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 - 1709.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 866.
3. Seacross Pharma (Europe) Ltd, Electronic medicines compendium (emc), [ Revised on March 2021] [ Accessed on 8th July 2021], https://www.medicines.org.uk/emc/files/pil.7206.pdf
4. Sanofi-aventis US LLC, US Food and Drug Administration, [ Revised on May 2020] [ Accessed on 8th July 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020449s084lbl.pdf
5. Angela M Davies et al; Docetaxel in non-small cell lung cancer: a review; Expert Opinion on Pharmacotherapy; Published on April 2003; Accessed on 02/12/2021; https://pubmed.ncbi.nlm.nih.gov/12667118/
6. Katherine A Lyseng-Williamson, Caroline Fenton; Docetaxel: a review of its use in metastatic breast cancer; Drugs; Published on 2005; Accessed on 02/12/2021; https://pubmed.ncbi.nlm.nih.gov/16296875/

How to use Docshil 120mg Injection:

It will be given to you by your health care professional.

Safety advice:

Pregnancy:

Docshil 120mg Injection can harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medicine.

Breastfeeding:

You must not breastfeed during the treatment with Docshil 120mg Injection and for 1 week after the last dose. Inform your doctor if you are breastfeeding before taking this medicine.

Liver:

Docshil 120mg Injection is contraindicated in patients with severe liver disorders. You need to tell your doctor if you have any liver disorders before taking this medicine. 

Kidney:

You need to tell your doctor if you have any kidney disorders before taking Docshil 120mg Injection.

Driving: 

Docshil 120mg Injection can cause dizziness and vision problems. Avoid driving if you are unwell.

Others:

• Inform your physician if you have low white blood cell count, heart problems, epilepsy, or alcohol addiction.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Severe allergic reactions (swelling of lips, tongue, or throat, difficulty breathing, swallowing, rash)
• Severe fluid retention (swelling in legs or feet, weight gain, shortness of breath)
• Severe skin problems (blistering, peeling, or bleeding on any part of your skin)
• Swelling of small intestine and colon (stomach pain or diarrhea with or without fever)

Common:

• Headache, dizziness
• Fever, infections
• Low blood cell count
• Loss of appetite
• Trouble sleeping
• Joint or muscle pain
• Alteration in the sense of taste
• Eye problems, bleeding from the nose
• Nausea, vomiting
• Diarrhea, constipation
• Abdominal pain
• Hair loss, change in color of your nails
• Change or absence of menstrual period
• Weight loss
• Tiredness
• Dry mouth
• High blood sugar
• Decreased blood pressure, rapid heartbeat

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.