• Chest, lung, or nasal infections
• Urinary tract infections
• Acne
• Eye infections
• Sexually transmitted diseases
• Fevers associated with tick bites

Doxific plus 100mg injection is in a class of medications called tetracycline antimicrobial drug. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit. It has bacteriostatic activity against a broad range of gram-positive and gram-negative bacteria. It works by killing bacteria that cause infections.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications like antacids, iron supplements may interact with Doxific plus 100mg injection and reduce its effectiveness by causing undesirable side effects. 

• Store the injection below 25°C
• Protect the medicine from light and excessive moisture.
• Keep the medicine out of reach of children and pets
• If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.

Doxific plus 100mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age. This medicine will be given intravenously (into your vein). Do not self-administer the injection. 

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

Common 

• Rash
• Diarrhea
• Loss of appetite
• Nausea, vomiting
• Sore gums
• Myalgia
• Bacterial vaginosis

Serious  

• Severe skin rash
• Liver injury
• Bone problems
• Infections

You should avoid direct sunlight while taking this medication since your skin may be more sensitive to sunburn than usual. If you experience severe, prolonged, or bloody diarrhea while taking Doxific plus 100mg injection, notify your doctor immediately because the medication may need to be stopped. When used for an extended period, the medication may induce infections. For 7 days, avoid teeth brushing, flossing, and other mechanical oral hygiene activities. Your doctor may suggest you undergo certain blood tests to assess the medication's efficacy and monitor any adverse effects. 

1. Doxycycline Hyclate for injection. Pfizer, [Published September 2013]. [Accessed May 2, 2023.] https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/050442s016lbl.pdf
2. KD Tripathi, Essentials of Medical Pharmacology, Tetracyclines and Chloramphenicol (Broad-spectrum Antibiotics), 7th edition, 2013, 733-737.
3. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Protein synthesis Inhibitors and Miscellaneous Antibacterial agents, 12th edition, 2011, 1521-1527.