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Doxorex PL 2mg Injection
Prescription Required
Salt Composition : Liposomal Doxorubicin
Manufacturer : SAMARTH LIFE SCIENCES PVT LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Doxorex Pl 2mg Injection
Doxorex PL 2mg Injection is an anticancer medication that contains the active constituent doxorubicin encapsulated in a closed lipid sphere (liposome). Cancer is a disease in which cells multiply in an uncontrolled and abnormal manner.
This medication is used to treat breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cell called plasma cell) and AIDS-related Kaposi’s sarcoma.
People with HIV infection have the highest risk of Kaposi’s sarcoma (cancer that forms in the lining of the lymph and blood vessels). Doxorex PL 2mg Injection may be given alone or in combination with other anticancer medicines. This medication is not recommended for adolescents and children.
Use effective birth control during the treatment and for at least six months after the last dose. It is important to tell your doctor if you are allergic to peanuts or soya if you are receiving medicines for heart or liver disorders, have diabetes, Kaposi’s sarcoma or oral problems before taking Doxorex PL 2mg Injection.
Uses of Doxorex Pl 2mg Injection
Doxorex PL 2mg Injection is used in the treatment of the following:
- Breast cancer
- Ovarian cancer
- Multiple myeloma
- AIDS-related Kaposi’s sarcoma
Therapeutic Effects of Doxorex Pl 2mg Injection
Doxorex PL 2mg Injection inhibits the enzyme topoisomerase II activity, which is involved in the DNA (genetic material) multiplication of cancer cells. This prevents the growth and multiplication of cancer cells.
The unique formulation process of Doxorex PL 2mg Injection increases the time this medicine is circulating in the blood. It also helps deliver drugs from blood to the cancerous tissue rather than the healthy tissue.
Interaction of Doxorex Pl 2mg Injection with other drugs
Inform your doctor about any medications you take or have taken before the treatment, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Doxorex PL 2mg Injection and can cause undesirable side effects.
More Information about Doxorex Pl 2mg Injection
- Keep Doxorex PL 2mg Injection out of sight and reach of children.
- Store refrigerated at 2°C - 8°C. Do not freeze.
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the injection, inform your healthcare professional immediately and reschedule the appointment.
How to consume Doxorex Pl 2mg Injection
A health care professional will give it to you. Your physician will decide your dose and frequency of administration based on your disease condition and other factors. Do not self-administer.
Safety Advices for Doxorex Pl 2mg Injection
Pregnancy
Doxorex PL 2mg Injection may harm the unborn baby. You must tell your physician if you are pregnant or planning to get pregnant before taking this medicine.
Breast Feeding
Stop breastfeeding before starting treatment with Doxorex PL 2mg Injection. You must tell your physician if you are breastfeeding before taking this medicine.
Lungs
It is unknown whether Doxorex PL 2mg Injection can be given to patients with lung diseases. Please consult your physician if you have any lung problems.
Liver
You must tell your physician if you have any liver disorders before taking Doxorex PL 2mg Injection.
Alcohol
It is unknown whether alcohol consumption is safe while you are undergoing a Doxorex PL 2mg Injection course. It is recommended to consult your doctor for better guidance
Driving
Doxorex PL 2mg Injection may cause tiredness or sleepiness. Avoid driving if you are unwell.
Side Effects of Doxorex Pl 2mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of Doxorex PL 2mg Injection are:
- Fever, tiredness, bruising or bleeding
- Severe diarrhoea, sores in the mouth, nausea, vomiting
- Lung infections, shortness of breath
- Severe stomach pain
- Severe weakness
Common side effects of Doxorex PL 2mg Injection are:
- Low blood cell counts
- Hair loss
- Decreased appetite
- Skin rashes
- Pain in the muscles and joints
- Constipation
- Feeling confused, difficulty sleeping
- Headache, dizziness, sleepiness
- Change in taste
- High or low blood pressure
- Excessive sweating
- Pain when passing urine
- Weight loss
- Muscle spasms
- Fast heartbeat
Word of Advice
Inform the doctor if the patient has allergic reactions, diabetes, blood pressure, kidney, liver diseases before taking this medication. Blood glucose levels, blood pressure, and liver and kidney function should be monitored regularly while taking this medication. Don't stop this medication without the proper advice of the doctor. Avoid making plans for pregnancy or during pregnancy, as this medication can cause harmful effects on the developing baby. Avoid driving after taking this medication because it causes dizziness and lack of concentration.
FAQs
Q 1. What is the use of Doxorex PL 2mg Injection?
This medication treats breast cancer, ovarian cancer, multiple myeloma (cancer of white blood cells called plasma cells), and AIDS-related Kaposi’s sarcoma.
Q 2. Is it safe to use Doxorex PL 2mg Injection during pregnancy?
It is unsafe to use this medication in patients who are planning for pregnancy or during pregnancy and breastfeeding mothers as it causes harmful effects for the baby.
Q 3. What are the side effects of Doxorex PL 2mg Injection?
The common side effects of these medications are nausea, vomiting, rash, weakness, low blood platelets, Fatigue, Fever, Loss of appetite, Anemia, and Constipation.
Q 4. How does Doxorex PL 2mg Injection work?
It damages the genetic material (DNA) of the cancer cells and stops their growth and multiplication
Q 5. Is it safe to use Doxorex PL 2mg Injection while driving?
No, using this medication while driving and handling heavy machinery is unsafe as it causes a lack of concentration and alertness.
Fact Box of Doxorex Pl 2mg Injection
Molecule name: Liposomal Doxorubicin | Therapeutic class: Antineoplastics |
Pharmacological class: Anthracyclines | Indications: 1. Breast cancer 2. Ovarian cancer 3. Multiple myeloma 4. AIDS-related Kaposi’s sarcoma |
References
1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
3. Baxter Holding BV, European medicines agency (ema), [Revised on May 2006] [ Accessed on 4th Dec 2021], https://www.ema.europa.eu/en/documents/product-information/caelyx-pegylated-liposomal-epar-product-information_en.pdf
4. Ben Venue Laboratories, Inc, US Food and Drug Administration, [Revised on May 2007] [ Accessed on 4th Dec 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/050718s029lbl.pdf
Disclaimer
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