• Adrenocortical insufficiency
• Congenital adrenal hyperplasia
• Arthritis (inflammation o joints)
• Allergic conditions
• Inflammatory disease of the eye
• Certain Cancer conditions
• Gastrointestinal diseases
• Collagen disorders like SLE (systemic lupus erythematosus)
• Skin problems like eczema, psoriasis, and dermatitis
• Asthma

Entofoam enema 20.8gm is a corticosteroid hormone (naturally occurring hormone cortisol), which is produced by the adrenal gland. Cortisol plays an important role in regulating inflammation and immune function. When there is an injury or infection, the body responds by increasing inflammation and immune activity to help fight off the threat. However, the inflammatory response can sometimes become excessive or misguided, leading to tissue damage or autoimmune disorders. 

This medication works by binding to specific receptors in the body and inhibiting the production of inflammatory chemicals and immune cells, thus reducing inflammation and suppressing the immune response. This can relieve pain, swelling, and redness and help prevent tissue damage and further complications.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with entofoam enema 20.8gm and reduce effectiveness by causing undesirable side effects.

• Entofoam enema 20.8gm should be stored at room temperature between 25°C.
• Keep away from heat, moisture, and light.
• Store in an original package.
• Keep out of reach of children and pets.

Entofoam enema 20.8gm is given as an intravenous or intramuscular injection by a healthcare professional. If you miss a dose, taking or applying it as soon as you remember is important. However, if it is close to the time for your next dose, it is best to skip the missed dose and resume your regular schedule. Do not double the dose to make up for the missed one.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Itching or skin rashes
• Swelling of lips, throat, or face
• Difficulty in breathing
• Depression and mood swings
• Cushing’s syndrome (reddish stretch marks, round red face, weak bones, and muscles)
• Bleeding ulcer (stomach pain, black stools, bleeding from back passage)
• Aseptic necrosis (hip or shoulder pain, joint inflammation of knee or groin)
• Inflammation of pancreas

Common:

• Headaches, dizziness
• Swollen ankles
• Feeling tiredness
• Increased appetite and weight gain
• Fluid retention and swelling in the face and limbs
• Elevated blood pressure
• Difficulty sleeping or insomnia
• Acne
• Increased susceptibility to infections
• Muscle weakness or wasting

Entofoam enema 20.8gm is a prescription medication that should only be used under the guidance and supervision of a qualified healthcare professional. Do not share your medication with others, and do not use it for any condition other than the one for which it was prescribed. Do not take more or less of the medication than prescribed, and do not stop taking the medication without first consulting with your healthcare professional.

Inform your healthcare professional immediately  if you experience any side effects or have any safety concerns, particularly if you have a history of liver disease, kidney disease, diabetes, or other medical conditions. They may need to adjust your dose or recommend an alternative treatment to ensure your safety and optimize treatment outcomes. If you have any questions or concerns about using this medication, speak with your healthcare professional.

1. Advanz Pharma Limited, Electronic medicines compendium (EMC), [Revised on 27 Feb 2023] [Accessed on Nov 2023], Hydrocortisone 100mg/ml solution for injection - Patient Information Leaflet (PIL) - (emc) (medicines.org.uk)
2. Pfizer., US Food and Drug Administration, [Revised on Nov 2019], [Accessed on Nov 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/519/008697s036lbl.pdf
3. KD Tripathi, Essentials of Medical Pharmacology, Corticosteroids, 7th edition, 513,282-293.
4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, ACTH, Adrenal Steroids and Pharmacology of the Adrenal Cortex,12th edition, 511, 1228-1229.