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Epitaz 50mg Injection
Salt Composition : Epirubicin
Manufacturer : INTAS PHARMACEUTICALS LTD
Origin of Medicine : India
Introduction to Epitaz 50mg Injection
Epitaz 50mg injection contains the active substance Epirubicin Hydrochloride. It is an antineoplastic drug that belongs to the class anthracyclines. This medicine is used as adjuvant therapy in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is also found useful in treating cancers of the breast, ovaries, stomach, bowel, and lung. In addition, this medicine is also used to treat cancers of the blood-forming tissues, such as malignant lymphomas, leukemias, and multiple myeloma.
Do not take this injection if you are allergic to epirubicin or any other ingredients of this medicine, pregnant or breastfeeding, or have severe liver and bladder problems. Before initiating the treatment, inform your physician if you have kidney or liver problems, recent vaccination, or if you have any acute toxicities such as acute inflammation of the mouth, low white blood cell count, platelet count, or any infections. This medicine may increase your risk of blood clots.
This medicine may cause infertility in men and women; inform your physician if you are planning for pregnancy. If you are sexually active, you are advised to use effective birth control to prevent pregnancy. Your doctor will do regular lab tests to check on the effects of this medicine. Common side effects of Epitaz 50mg injection are decreased WBC, platelets, irregular menstruation, weakness, nausea or vomiting, diarrhea, eye infection, skin rashes, or itchiness.
Uses of Epitaz 50mg Injection
- Breast cancer
- Stomach and bowel cancer
- Ovarian cancer
- Lung cancer
Therapeutic Effects of Epitaz 50mg Injection
Epitaz 50mg injection inhibits DNA, RNA, and protein synthesis by exerting cytotoxic activity. It works by slowing or stopping the growth of the cancer cells. This medicine helps to selectively kill cancer cells rather than normal, healthy cells.
Interaction of Epitaz 50mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescription, over-the-counter, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Epitaz 50mg injection and reduce its effectiveness by causing undesirable side effects.
More Information about Epitaz 50mg Injection
- Store Epitaz 50mg injection in the refrigerator (2°C to 8°C)
- Do not freeze
- keep the injection away from the reach of children and pets.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Epitaz 50mg Injection
It should only be administered by a trained doctor or nurse experienced in giving chemotherapy. The medicine will be given as an infusion into a vein. Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity and other factors.
Safety Advices for Epitaz 50mg Injection
Epitaz 50mg injection is unsafe to administer in pregnant women because it may cause severe birth defects. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6.5 months after your last dose is necessary.
Breastfeeding is not recommended in patients taking Epitaz 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby.
It is unknown whether Epitaz 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Epitaz 50mg injection should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary. Inform your physician if you have liver problems before initiating the therapy.
It is unknown whether consuming alcohol will affect the effectiveness of Epitaz 50mg injection. Consult your doctor for more advice.
Epitaz 50mg injection does not affect the ability to drive or operate heavy machines. If you face any difficulties in driving, please consult your doctor.
Side Effects of Epitaz 50mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Hair loss
- Rash, itching
- Nausea and vomiting
- Decreased WBC and platelets
- Eye infection
- Irregular menstruation
- Congestive heart failure
- Increased blood urea levels
- Severe hypersensitivity reaction
- Lung problems
Word of Advice
Inform your physician if you are receiving radiation therapy with this medicine. This medicine may cause birth defects if either partner uses it during conception or pregnancy. Male patients with female partners of reproductive potential should use effective birth control during the treatment and for 3 months after the last dose. Do not breastfeed during the treatment and for 7 days after the last dose. The medicine may turn your urine red for 1 or 2 days after your treatment.
Q 1. How long should I have to take Epitaz 50mg injection?
Epitaz 50mg injection is given as a cycle therapy. Your doctor will decide the dose and duration of the therapy based on your disease severity and condition.
Q 2. What if Epitaz 50mg injection does not work for me?
There are alternative medicines that may work for you based on your disease condition and other factors. Your doctor will decide the alternative treatment tha works best for you.
Q 3. What are the precautions of Epitaz 50mg injection?
This medicine may increase your risk of developing blood clots. If you have chest pain, trouble breathing, or pain, redness, or swelling in your arms or legs while using this medicine, call your doctor immediately. This medicine may turn your urine red for 1 or 2 days after your treatment.
Q 4. Is there any special diet that I should follow while taking Epitaz 50mg injection?
There are no special restrictions on the diet. If your doctor or any other healthcare professional tells you to avoid certain food, then avoid it. Diet restrictions may vary from patient to patient. Consult your doctor for more advice.
Fact Box of Epitaz 50mg Injection
Molecule name: Epirubicin
Therapeutic class: Antineoplastics
Pharmacological class: Antimetabolite
1. Breast cancer
2. Stomach and bowel cancer
3. Ovarian cancer
4. Lung cancer
- Epirubicin hydrochloride 2 mg/ml solution for injection - Summary of Product Characteristics (SmPC) - (emc). Medicines.org.uk. [revised on 2016] [cited 2023 Mar 31]. Available from: https://www.medicines.org.uk/emc/product/6361/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION - Epirubicin. [revised on 2019] [cited 2023 Mar 31]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050778s024s025lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.
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