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Estofert TG Gel
Prescription Required
Salt Composition : Estradiol
Manufacturer : GUFIC BIOSCIENCE LTD
Origin of Medicine : India
1 Tube(s)
Introduction to Estofert Tg Gel
Estofert TG Gel contains an active ingredient called estradiol which belongs to a group of medicines called vaginal Hormone Replacement Therapy (HRT). It falls within the category of hormones known as estrogens and shares identical properties with the naturally occurring Estofert TG Gel is synthesised by women's ovaries. It is indicated to treat menopausal symptoms such as 'vaginal atrophy' (dryness or irritation of the vagina) in elderly women who have passed the stage of menopause.
It is not recommended to use Estofert TG Gel if you are allergic to the active compound estradiol and its constituents. It is not advised to use Estofert TG Gel if you have breast cancer or any type of cancer that is oestrogen receptor sensitive. It is not recommended to use Estofert TG Gel if you have a clotting disorder or blood clot in veins (lungs or legs) and unexplained vaginal bleeding.
It is not advised to consume Estofert TG Gel if you have a heart attack, stroke, angina or abnormal liver function tests. It is not given to patients with a rare inherited blood disorder called porphyria. The risk of gallbladder disease is elevated by estrogen intake. Stop using estrogen if you experience cholestatic jaundice, severe hypertriglyceridemia, severe hypercalcemia, or vision loss. It is advised to keep an eye on women receiving thyroid replacement treatment.
Inform your doctor if you have vaginal bleeding, heart, kidney, lung or liver problems, diabetes, asthma, high blood pressure, or hearing disorder. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding. Speak with your doctor about your medical history to the doctor. It is necessary to inform your healthcare provider about all the medicines you are taking, including herbal, vitamin, and over-the-counter medicines.
Uses of Estofert Tg Gel
- Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation)
- Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism
- Preventing osteoporosis after menopause
Therapeutic Effects of Estofert Tg Gel
Estofert TG Gel primarily acts by binding to estrogen receptors (ERs) present on the surface of target cells upon binding to its receptor, Estofert TG Gel induces a conformational change in the receptor, leading to its activation. Estofert TG Gel replaces estrogen (female sex hormone) and prevents the symptoms of menopause, like vaginal irritation or dryness.
Interaction of Estofert Tg Gel with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Estofert TG Gel and can cause undesirable side effects.
More Information about Estofert Tg Gel
- Protect from moisture
- Store Estofert TG Gel at 25˚C
- Keep children away from the sight and reach of this medication.
How to consume Estofert Tg Gel
Take Estofert TG Gel exactly as prescribed by your healthcare provider. Do not adjust the dosage or frequency without consulting your doctor. Take your Estofert TG Gel at the same time each day to maintain a consistent level of hormones in your body. Swallow the Estofert TG Gel whole with a glass of water. Do not crush, chew, or break the tablet, as this may affect its effectiveness or increase the risk of side effects.
Safety Advices for Estofert Tg Gel
Pregnancy
Estofert TG Gel is not recommended for pregnant women. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant.
Breast Feeding
It is unknown whether Estofert TG Gel is excreted in breast milk. Consult your doctor before using it. Seek your doctor for more information.
Lungs
Inform your physician about any underlying lung disorders before taking Estofert TG Gel, as this medication should be used cautiously in lung disease patients.
Liver
Inform your physician about any underlying liver disorders before taking Estofert TG Gel, as this medication should be used cautiously in liver disease patients.
Alcohol
It is unknown whether it is safe to consume alcohol under medication. So, it is recommended to consult your doctor before taking medicine.
Driving
It is unknown whether Estofert TG Gel alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Side Effects of Estofert Tg Gel
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common
- Headache
- Stomach pain
- Vaginal bleeding
- Discharge or discomfort.
Serious:
- Ovarian cancer
- Blood clots
- Heart attack
- Breast lumps
- Stroke
Word of Advice
It is recommended to examine your breast (mammogram) to avoid the risk of breast cancer caused by the drug and inform your doctor if you have any changes in skin colour. Don't apply it on your breast, eye, or other part of the body apart from the application site. Inform your doctor if you have uterus cancer or a history of blood clots. Regularly monitoring liver function tests, thyroid tests, bone mineral density, and blood pressure is advised as treatment with Estofert TG Gel can alter these values.
FAQs
Q 1. What are the precautions I need to take while taking Estofert TG Gel?
Inform your medical history to the doctor. It will be useful for him to treat you based on your health. Inform your doctor if you have kidney, liver, or heart disease, diabetes, gallbladder problems, or asthma before starting to use the medicine.
Q 2. Can I suddenly stop taking Estofert TG Gel?
Stopping your Estofert TG Gel treatment suddenly without first talking to your doctor is not advised. When estrogen medication is abruptly stopped, withdrawal symptoms and maybe rebound effects might occur. Talk to your healthcare practitioner about stopping or altering your therapy so that a safe and gradual plan may be created.
Q 3. Can I take Estofert TG Gel if I have a history of allergies to it?
Consult your doctor if you are allergic to Estofert TG Gel or any of the ingredients should be used before starting the medicine.
Q 4. What happens if a pregnant woman takes Estofert TG Gel?
Estofert TG Gel is not recommended for premenopausal women or pregnant women, as it may cause undesirable side effects if it is used during the period of pregnancy.
Q 5. Is there any possibility of having breast cancer when I use Estofert TG Gel?
Yes, Estofert TG Gel may cause breast cancer as a side effect. So, it is advised that you examine your breasts while under medication.
Fact Box of Estofert Tg Gel
Molecule name: Estradiol | Therapeutic class: Hormones |
Pharmacological class: Androgens | Indications: 1. Relieve menopausal symptoms of 'vaginal atrophy' (in the vagina such as dryness or irritation) 2. Treatment for hypogonadism, castration, or primary ovarian failure-related hypoestrogenism 3. Preventing osteoporosis after menopause |
Dosage form: Tablet | Habit forming: No
|
References
- Mercury Pharmaceuticals Limited, Electronics Medicines Compendium (EMC), [Revised on Jan 2024], [Accessed on 13th March 2024] , https://www.medicines.org.uk/emc/files/pil.11779.pdf
- Ther-Rx Corporation, US Food and Drug Administration,[Revised on April 2008], [Accessed on 13th March 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022014s001lbl.pdf
- Pfizer, [Revised on Feb 2024], [Accessed on 13th March 2024], https://labeling.pfizer.com/ShowLabeling.aspx?id=595
- Novartis Pharmaceuticals Corporation, [Revised on October 2021], [Accessed on 13th March 2024], https://www.novartis.com/us-en/sites/novartis_us/files/Vivelle_DOT.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Androgens and drugs for erectile dysfunction, 7th edition, 2013, 296-300.
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