ETHYFOS 500MG INJECTION

Introduction:

Ethyfos 500mg Injection is a cytoprotective agent containing the active constituent Amifostine. It is used to prevent or reduce the undesirable side effects of certain chemotherapy medications and radiation therapy. It is specially used to protect the kidneys and nervous system from harmful effects of the anticancer medicine cisplatin in patients with advanced ovarian cancer.

It is also used to treat radiation therapy-related xerostomia. Xerostomia is a dry mouth resulting from the absence of saliva, which is a sign of various medical complications. You need to inform your physician about all the medications you are taking recently and if you have or have ever had any heart disorders before starting treatment with Ethyfos 500mg Injection.

Drink plenty of liquids prior to therapy. Nausea, vomiting, and low blood pressure are the common side effects of Ethyfos 500mg Injection. 

Uses of Ethyfos 500mg Injection:

• Reduction of harmful effects on kidneys and nervous system by chemotherapy medication
• Treats the radiation-therapy induced xerostomia

How Ethyfos 500mg Injection works:

It works by binding to the harmful elements produced from cisplatin or radiation therapy in the body and removing or deactivating them.

Interactions with other drugs:

Inform your doctor about any medications you are taking or have taken before the treatment.

More information:

Store the medicine at controlled room temperature 20°C - 25°C protected from light. 

References:

1. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 876.
2. Cumberland Pharmaceuticals Inc, US Food and Drug Administration, [Revised date May 2017], [Accessed date 26th Nov  2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/020221s033lbl.pdf

How to use Ethyfos 500mg Injection:

It will be given to you by your health care professional.

Safety advice:

Pregnancy: 

The use of Ethyfos 500mg Injection should be avoided during the pregnancy as it can cause harm to the unborn baby. Consult your doctor for the potential risks of this medication. It will be given to you only if clearly needed.

Breastfeeding:                               

The use of Ethyfos 500mg Injection should be avoided during breastfeeding. Consult your doctor for potential risks and benefits.

Others:

• Inform your doctor if you have any heart disorders, low blood pressure, or dehydration.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.

Serious:

• Shortness of breath, difficulty swallowing
• Peeling or blistering skin
• Chest pain, tightness
• Seizures
• Blurred vision, fainting
• Fast or slow heartbeat

Common:

• Nausea, vomiting
• Low blood pressure
• Hiccups
• Chills
• Sleepiness, dizziness
• Flushing
• Sneezing