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Fludabine 10mg Tablet
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Introduction to Fludabine 10mg Tablet
Fludabine 10mg Injection is a chemotherapy medication containing the active ingredient fludarabine. It is used to treat B-cell chronic lymphocytic leukemia (CLL). Chronic lymphocytic leukemia is cancer of white blood cells (disease-fighting agents) in which the body produces many abnormal white blood cells, and lymph nodes start to grow in various parts of the body. This can lead to organ failure, decrease in red blood cells, severe bleeding and infections.
Fludabine 10mg Injection is not recommended for adolescents and children under 18 years of age, breastfeeding patients, and patients with severe kidney problems or low red blood cell count. Use effective birth control methods during the treatment with this medicine and for at least six months from the last dose. Avoid live vaccination while taking this medicine. Report to your doctor if you experience any allergic reactions while taking Fludabine 10mg Injection.
Uses of Fludabine 10mg Tablet
- Treatment of B-Cell chronic lymphocytic leukemia (blood cancer)
Therapeutic Effects of Fludabine 10mg Tablet
Fludabine 10mg Injection works by decreasing or stopping the growth of cancer cells by inhibiting the DNA synthesis in cancer cells.
Interaction of Fludabine 10mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Fludabine 10mg Injection and cause undesirable side effects.
More Information about Fludabine 10mg Tablet
- Keep Fludabine 10mg Injection out of sight and reach of children.
- Store in a refrigerator (2°C to 8°C).
How to consume Fludabine 10mg Tablet
This injection should not be self administered and it should be taken only under the supervision of the doctors or nurse. Dosage of this injection will differ depending upon the patient’s age and severity of the condition.
Safety Advice for Fludabine 10mg Tablet
Breast Feeding
Breastfeeding is not recommended during treatment with Fludabine 10mg Injection. Consult your doctor for advice
Alcohol
Consult your doctor regarding advice on alcohol consumption before starting treatment with Fludabine 10mg Injection.
Liver
It is essential to inform your doctor if you have any liver disorders before taking this medicine.
Lungs
Talk to your doctor if you have any lung conditions before starting treatment with Fludabine 10mg Injection.
Driving
Fludabine 10mg Injection may cause tiredness or disturbed vision. Avoid driving if you are unwell.
Pregnancy
Fludabine 10mg Injection is not recommended for use in pregnancy. Your doctor will prescribe the medication if the benefits outweigh the risks.
Side Effects of Fludabine 10mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Lung infection (cough, chest pain, difficulty breathing)
- Unusual bleeding or bruising
- Blood in urine, reduced amount of urine, or pain in your side
- Skin reactions (redness, inflammation, or blistering)
- Palpitations
Common
- Diarrhea
- Fever
- Weakness, tiredness
- Nausea, vomiting
- Low blood count
- Infections
Word of Advice
Inform the doctor if the patient has any history of kidney, liver, allergic reactions before starting this medication. Avoid taking this medication while planning for pregnancy or during pregnancy as it causes harmful effects on developing babies. This injection is not recommended in children below 18 years of age. Avoid driving or handling heavy machinery while taking this injection as they cause disturbed vision. patient’s may lack concentration and alertness.
FAQs about Fludabine 10mg Tablet
Q1.
Can Fludabine 10mg injection be given in children?
No, this injection is not recommended in the children below 18 years of age as it causes severe complications. consult the doctor before using this injection.
Q2.
Can Fludabine 10mg injection be used in kidney patients?
No, this injection is contraindicated in the patients with severe kidney disorders. Consult the doctor before taking this medication.
Q3.
Can I use Fludabine 10mg injection while driving?
Avoid driving or handling heavy machinery while taking this injection as they cause disturbed vision. patient’s may lack concentration and alertness.
Q4.
Can Fludabine 10mg injection be given if blood count is low?
No, this injection is not recommended in the patient with anemia and in other conditions where the blood count is low. Inform the doctor before taking this injection.
Q5.
Can Fludabine 10mg injection be used during pregnancy?
It is unsafe to use this injection during pregnancy as it causes harmful effects in the developing baby.
Q6.
Can Fludabine 10mg injection be self administered?
No. This injection should be given only under the supervision of the doctor or nurse and it should not be self administered.
Fact Box of Fludabine 10mg Tablet
Molecule name: Fludarabine | Therapeutic class: Antimetabolites |
Pharmacological class: Purine analog | Indications: 1. Treatment of B-Cell chronic lymphocytic leukemia (blood cancer) |
References
1.KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 864.
2.Accord Healthcare Limited, Electronic medicines compendium (emc), [Revised on Dec 2019] [ Accessed on 30th Nov 2021], https://www.medicines.org.uk/emc/files/pil.3393.pdf
3.Emcure Pharmaceuticals Ltd, [Revised on Dec 2018] [ Accessed on 30th Nov 2021], https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Fludara-IV_PI-201812.pdf
4.Joshua Lukenbill, Matt Kalaycio; Fludarabine: a review of the clear benefits and potential harms; Leukemia Research (Published on Sept 2013; Accessed on 30/11/2021) https://pubmed.ncbi.nlm.nih.gov/23787174/
Disclaimer
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Author Details
Written By
Guruvigneshwari M.
M. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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