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Gefzest 250mg Tablet 30's
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Introduction to Gefzest 250mg Tablet 30's
Gefzest Tablet is an antineoplastic drug belonging to the tyrosine kinase inhibitors, containing the active ingredient Gefitinib. It is used to treat non-small cell lung cancer. Non-small cell lung cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner in the tissues of the lung. It is used in patients where the NSCLC cancer has spread to other parts of the body, who have certain types of abnormal epidermal growth factor (EGFR) genes, and patients who have not received any cancer treatment.
Some formulations of this drug may contain lactose as an inactive ingredient, which the body is unable to digest. Lactose is a sugar found in milk and dairy products. It can cause symptoms such as bloating and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy. Talk with your healthcare provider if you have kidney or liver disease, vision problems, lung problems, or taking any blood thinner like warfarin. Your healthcare provider will check regular blood tests to prevent complications. Avoid consuming alcohol as it may cause dizziness.
Consult your doctor before using this medication if you are pregnant or plan to have a baby. These tablets are unsafe to use during pregnancy as they cause harm to an unborn fetus. Your healthcare practitioner will conduct a pregnancy test before you start treatment with this tablet. Discuss with your doctor effective birth control methods and utilize them for at least two weeks following the last dose. Avoid breastfeeding your baby while on the treatment as it is unknown if this drug passes into the breast milk.
Uses of Gefzest 250mg Tablet 30's
Gefzest Tablet is used to treat
- Non-small cell lung cancer.
Therapeutic Effects of Gefzest 250mg Tablet 30's
It is an anilinoquinazoline derivative that interacts with a kinase inhibitor that inhibits an abnormal protein called the epidermal growth factor receptor (EGFR). This helps to slow or stop the growth of cancer cells and reduce the size of tumors in patients with NSCLC.
Interaction of Gefzest 250mg Tablet 30's with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Gefzest Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Gefzest 250mg Tablet 30's
- Store Gefzest Tablet in the original package at room temperature (25°C).
- Keep it out of reach from children.
- If you have missed any dosing appointments, inform your doctor and schedule immediately.
How to consume Gefzest 250mg Tablet 30's
The medicine will be prescribed to you by a healthcare professional in a hospital setting. This drug is available as a tablet to be taken with or without food, as directed by your healthcare provider. The usual recommended dosage is 250 mg tablet once daily. Avoid crushing, opening, or dissolving the tablet. Swallow it whole with a glass of water. Take the Gefzest Tablet at the same time every day.
Safety Advice for Gefzest 250mg Tablet 30's
Breast Feeding
It is unsafe to breastfeed during the treatment with this Gefzest Tablet because it may cause harm to the baby. Please consult your doctor before breastfeeding.
Alcohol
It is unknown whether consuming alcohol interacts with the Gefzest Tablet. Please consult your doctor for more advice.
Liver
It is unknown whether the Gefzest Tablet can be used for patients with liver disorders. Inform your physician if you have any liver problems before starting treatment.
Lungs
It is unknown whether Gefzest Tablet can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking the Gefzest Tablet because it contains a small amount of alcohol, which may cause dizziness and impair your concentration.
Pregnancy
It is unsafe to use during pregnancy whether Gefzest Tablet can be taken during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects of Gefzest 250mg Tablet 30's
.Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- diarrhea
- nausea
- vomiting
- loss of appetite
- weakness
- red or sore mouth
- increased liver enzymes
- itchy or cracked skin
- dry mouth
- red or itchy eyes
- nail problems
- hair loss
- fever
- blood in the urine and burning sensation while urinating
Word of Advice
Gefzest Tablet is not recommended for children and adolescents below 18. It is advisable to monitor your blood pressure regularly during this treatment. Avoid high-fiber foods and drink lots of fluids if you have severe diarrhea. Antacids should not be used two hours before or one hour after taking this tablet. Avoid driving and operating heavy machinery if you feel tired or weak during this treatment.
FAQs about Gefzest 250mg Tablet 30's
Q1.
What are the Gefzest Tablet side effects?
Diarrhea, nausea, vomiting, loss of appetite, weakness, red or sore mouth, increased liver enzymes, itchy or cracked skin, dry mouth, dry, red or itchy eyes, nail problems, hair loss, fever, nosebleed, blood in the urine and burning sensation while urinating are the common Gefzest Tablet side effects.
Q2.
Is Gefzest Tablet targeted therapy?
Yes, Gefzest Tablet is a targeted drug therapy that helps to treat advanced non-small-cell lung cancer (NSCLC).
Q3.
Who should not use Gefzest Tablet?
Gefzest Tablet is not indicated for children and adolescents under the age of 18. It should not be used in people who are allergic to this drug, as well as pregnant or breastfeeding women.
Q4.
Is it safe for women of reproductive potential to use Gefzest Tablet?
Gefzest Tablet are not recommended for use during pregnancy and breastfeeding. Tell your healthcare provider before starting this treatment if you are pregnant, think you might be pregnant, breastfeeding, or planning to have a baby.
Q5.
What should I avoid while taking Gefzest Tablet?
It is advised to avoid taking an antacid or stomach acid-reducing medication within two hours before or one hour after taking a Gefzest Tablet.
Fact Box of Gefzest 250mg Tablet 30's
Molecule name: Gefitinib | Therapeutic class: Antineoplastics |
Pharmacological class: tyrosine kinase inhibitors | Indications: 1.Non-small cell lung cancer |
References
- Accord Healthcare SLU, Electronic medicines compendium (EMC), [Revised on Feb 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.7235.pdf
- Fresenius kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.
Disclaimer
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Author Details
Written By
Dr. Deva Prasath S.
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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