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Gembin 1000mg Injection
Salt Composition : Gemcitabine
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
Introduction to Gembin 1000mg Injection
Gembin 1000mg Injection is a chemotherapy medication containing the active ingredient gemcitabine. It is used to treat bladder cancer, breast cancer, ovarian cancer, pancreatic cancer, and non-small cell lung cancer. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. Talk to your doctor if you have heart disease, liver disorders, kidney disorders, recently had radiotherapy, or vaccinated before taking this medicine.
Gembin 1000mg Injection is not recommended for adolescents and children under the age of 18. Your doctor will assess your blood cell counts and kidney and liver function each time you are given this medicine. Use effective birth control during the treatment and at least six months after the last dose. This injection may impair fertility in male patients. Men taking this medicine are advised not to father a child during the treatment and for 6 months after the treatment.
Tell your physician if you are on a salt-controlled diet, as this medicine contains sodium. Report to your doctor immediately if you experience shortness of breath, wheezing, changes in color or volume of urine, bleeding, or upper abdominal pain while taking Gembin 1000mg injection.
Uses of Gembin 1000mg Injection
Gembin 1000mg injection is used to treat
- Bladder cancer, in combination with cisplatin
- Ovarian cancer, in combination with carboplatin
- Breast cancer, in combination with paclitaxel
- Pancreatic cancer
- Non-small cell lung cancer (NSCLC), alone or in combination with cisplatin
Therapeutic Effects of Gembin 1000mg Injection
Gembin 1000mg injection blocks the ability of cancer cells to process DNA replication, which is essential for the cells to divide and grow. This can prevent or stop the growth of cancer cells.
Interaction of Gembin 1000mg Injection with other drugs
Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interacting with Gembin 1000mg may reduce effectiveness by causing undesirable side effects.
More Information about Gembin 1000mg Injection
- Keep Gembin 1000mg injection out of sight and reach of children.
- This medicine does not require any special storage conditions.
- Do not refrigerate or freeze.
How to consume Gembin 1000mg Injection
Gembin 1000mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices for Gembin 1000mg Injection
Gembin 1000mg injection can cause harm to your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this treatment.
You must not breastfeed while being treated with Gembin 1000mg Injection. Inform your doctor if you are breastfeeding before taking this injection.
Gembin 1000mg injection is used cautiously in a patient with a lung disorder. Inform your doctor if you have any lung disease.
You need to tell your doctor if you have any liver disorders before taking Gembin 1000mg Injection. Your doctor may decide to adjust the dose or delay treating you depending on your liver function.
It is not advised to take alcohol while under this treatment because Gembin 1000mg may cause drowsiness and sleepiness. Talk to your doctor for more information.
Gembin 1000mg injection could affect your ability to drive. Avoid driving while taking this medicine. Talk to your doctor for more information.
Side Effects of Gembin 1000mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Pulmonary toxicity (shortness of breath, wheezing, cough)
- Hemolytic-uremic syndrome (Changes in the volume or colour of urine, increased bruising, or bleeding)
- Pain or tenderness in the upper abdomen
- Allergic reactions, rashes, fever, swelling or sores in the mouth
- Nausea, vomiting
- Low blood cell count
- Loss of appetite
- Hair loss
- Swelling of ankles, feet, and fingers
- Constipation, diarrhea
- Runny nose, chills
- Muscle pain, back pain
- hair loss
- liver problems
- blood in urine
- abnormal urine test
- Oedema (swelling of ankles, fingers, feet, face)
Word of Advice
It is not recommended to take Gembin 1000mg injection if you are allergic to Gemcitabine or any of its ingredients. During this treatment, your doctor may periodically monitor your complete blood counts, blood sugar, electrolytes, liver panel, and kidney parameters to prevent serious complications. This injection may impair fertility in male patients. Men taking this injection are advised not to father a child during the treatment and for 6 months after the treatment. Consult your doctor before starting this injection, and it is advised to get suggestions about fertility concerns from your doctor. It is advised for both men and women to follow proper contraceptive methods during and after the 6 months of the last dose.
Q 1. How does Gembin 1000mg affect cancer cells differ from healthy cells?
Gembin 1000mg affects cancer cells more than healthy cells because cancer cells have a higher rate of DNA synthesis and replication than healthy cells. This medicine interferes with this process, which is essential for cancer cell growth and division, ultimately leading to the death of cancer cells.
Q 2. Can Gembin 1000mg be used to treat cancer in children?
No, Gembin 1000mg injection is not recommended for adolescents and children under the age of 18.
Q 3. What should I tell my doctor before starting Gembin 1000mg treatment?
Patients should inform their doctor of any pre-existing medical conditions, allergies, or medications they are taking before starting Gembin 1000mg treatment. It is also important to inform the doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Q 4. Are there any dietary or lifestyle changes that patients should make while taking Gembin 1000mg ?
Patients may need to make dietary or lifestyle changes while taking Gembin 1000mg , such as avoiding certain foods or activities that may interfere with the medication's effectiveness or cause side effects. This should be discussed with a healthcare professional.
Q 5. Does Gembin 1000mg cure cancer?
Gembin 1000mg can help slow the growth and spread of cancer cells, but it may not cure cancer on its own. It is often used in combination with other treatments, such as surgery, radiation therapy, or other chemotherapy medications, to improve the chances of a cure or long-term remission.
Q 6. How long does Gembin 1000mg treatment last?
The duration of Gembin 1000mg treatment will depend on the type and stage of the cancer being treated, as well as the patient's overall health and response to the medication. Treatment may last several weeks or months.
Fact Box of Gembin 1000mg Injection
Molecule name: Gemcitabine
Therapeutic class: Anti-Cancer
Pharmacological class: Antimetabolites
Gembin 1000mg injection is used to treat
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1700.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 870.
- Sun Pharmaceutical Industries, Electronic medicines compendium (emc), [ Revised on May 2022] [ Accessed on 20 Mar 2023], https://www.medicines.org.uk/emc/files/pil.7298.pdf
- Hospira, Inc, US Food and Drug Administration, [ Revised on June 2019 [ Accessed on 20 Mar 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020509s077lbl.pdf
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