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  3. Graafipure 150IU Injection

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Quick summary
Quick Summary

Graafipure 150IU Injection

Prescription Required
Cold Chain Required
menotrophin
Written By:Dr. Vijayalakshmi N.BDS Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:29 AM (IST)

₹922

MRP: ₹2048

(You Save ₹1126)

1 VIAL(s)

55% OFF
Graafipure 150IU Injection
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4.8 ⭐️ On Google

Graafipure 150IU Injection


Prescription Required
Required
Cold Chain Required
Cold Chain
Info

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MENOTROPHIN

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ERMINNE PHARMACEUTICALS


Prepaid Only. Non-Returnable.

Info

55% OFF

Graafipure 150IU Injection
Preview
We are Rated 4.8 ⭐️ On Google

₹922

MRP: ₹2,048.00

Inclusive of all taxes

55% Off

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1 Vial(s)

1 Vial(s)

₹ 922.0/Unit

1 VIAL(s)


Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

MENOTROPHIN

Marketer

ERMINNE PHARMACEUTICALS


Prepaid Only. Non-Returnable.

Info
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Substitutes

Puregraf 150IU Injection

GUFIC BIOSCIENC...

₹ 762.00/injection

17% cheaper

Eugon HP 150IU Injection

SAMARTH LIFE SC...

₹ 802.00/injection

13% cheaper

Ovutas HP 150IU Injection

INTAS PHARMACEU...

₹ 835.00/injection

9% cheaper

Puregraf 150IU Injection PFS

GUFIC BIOSCIENC...

₹ 952.00/injection

4% costlier

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Introduction to Graafipure 150IU Injection

Graafipure 150IU Injection contains the active substance Menotrophin. It is an ovulation stimulator that belongs to the group of medications called gonadotropins. It is a highly purified mixture of follicle-stimulating hormone (FSH) and luteinising hormone (LH). They are natural hormones produced in both males and females. They help the reproductive organs to work normally.  

Graafipure 150IU Injection is used to treat infertility in women who are not ovulating, including those with polycystic ovarian disease, and who have not responded to treatment with another medicine called clomiphene citrate. It is also used to help multiple follicles and, therefore, to promote fertility in women undergoing IVF (in-vitro fertilisation)  or other types of assisted conception. It is also indicated to treat infertility in men due to low sperm count. 

Do not take Graafipure 150IU Injection if you are allergic to menotrophin or any of the other ingredients of this medicine. Do not take this medicine if you have a tumour in the pituitary gland  (a gland located on the base of the brain which produces certain hormones, including growth hormones)  or in the hypothalamus (an area located under the part of the brain called the thalamus which controls the conditions within your body including body temperature and blood pressure) or in the uterus, ovaries, breast, testicles, or in the prostate gland. Before initiating the treatment, you will be checked for underactive thyroid problems, hormone levels, and tumours of the pituitary and hypothalamus.

Do not take this medicine if you have ovarian cysts that are not due to PCOD, vaginal bleeding, early menopause, physical problems in the reproductive organs if your womb has been removed, and if you are pregnant or breastfeeding. Inform your physician immediately if you face any of these symptoms, such as abdominal pain and swelling, weight gain, diarrhoea, difficulty in breathing, and decreased urination. Inform your physician if you have or have had a liver problem or a history of blood clotting disease before starting the treatment.

Uses of Graafipure 150IU Injection

  • Infertility in men and women

Therapeutic Effects of Graafipure 150IU Injection

In the absence of sufficient endogenous luteinising hormone (LH), menotrophin binds to the follicle-stimulating hormone receptor (FSH), resulting in ovulation. It also attaches to the LH receptor, causing appropriate hormone release and treating infertility in women and men.

Interaction of Graafipure 150IU Injection with other drugs

nform your healthcare provider about all the medicines that you take, including prescription, over-the-counter, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with Graafipure 150IU Injection and reduce its effectiveness by causing undesirable side effects.

More Information about Graafipure 150IU Injection

  • Do not store above 25°C
  • Do not freeze
  • keep the injection away from the reach of children and pets.

How to consume Graafipure 150IU Injection

It will be given to you by a doctor or nurse in a hospital or clinic setting. It is given as an intramuscular injection (into your muscles) or under the skin. Do not self-administer the injection. Your doctor will decide the dose, route of administration and duration of the treatment based on your disease severity, body weight, and other factors.

Safety Advice for Graafipure 150IU Injection

Breast Feeding-unsafe

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Graafipure 150IU Injection because the medicine passes into the breast milk in small amounts and may harm your baby.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol is safe during the treatment with Graafipure 150IU Injection. Inform your doctor if you are a chronic drinker.

Liver-Consult your doctor

Liver

Consult Your Doctor

It is unknown whether Graafipure 150IU Injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Graafipure 150IU Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Driving-safe

Driving

Safe

Graafipure 150IU Injection does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.

Pregnancy-unsafe

Pregnancy

Unsafe

Graafipure 150IU Injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.

Side Effects of Graafipure 150IU Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common side effects of Graafipure 150IU Injection are:

  • Abdominal pain or swelling
  • Headache
  • Nausea
  • Pelvic pain
  • Overstimulation of ovaries
  • Pain or inflammation at the injection site
  • Mood swings

 

Serious side effects of Graafipure 150IU Injection are: 

  • Severe allergic reactions (hypersensitivity reactions)

Word of Advice

If you have missed any dosing appointments, inform your doctor and schedule immediately. This medicine can increase your risk of ectopic pregnancy (pregnancy outside of the womb) if you have a history of fallopian tube disease, miscarriage, multiple pregnancies (twins and triplets), and birth defects in the baby. Your doctor will regularly perform ultrasound scans and blood tests to monitor your response to the treatment.

FAQs about Graafipure 150IU Injection

Q1.

What is the purpose of using Graafipure 150IU Injection in fertility treatments?

Graafipure 150IU Injection is used in fertility treatments to help multiple follicles and stimulate the ovaries in women who are undergoing assisted reproductive technologies such as in vitro fertilisation (IVF) or intrauterine insemination (IUI). It helps promote the growth, maturation, and release of eggs from the ovaries in women who are not ovulating, including those with PCOD, and who have not responded to treatment with another medicine called clomiphene citrate.

Q2.

What are the possible side effects of Graafipure 150IU Injection? 

Common side effects of Graafipure 150IU Injection may include injection site reactions, abdominal discomfort, bloating, breast tenderness, headache, and mood swings. However, individual responses may vary, and it is important to discuss any concerns or unexpected side effects with a healthcare professional.

Q3.

Can Graafipure 150IU Injection be used in men for fertility treatment?

Graafipure 150IU Injection is primarily used in women to stimulate ovulation and promote fertility. It is also used to treat infertility in men due to low sperm count. If you have concerns about male fertility, it is recommended to consult with a healthcare professional for appropriate evaluation and guidance.

Q4.

Can Graafipure 150IU Injection increase the chances of multiple pregnancies?

Yes, the use of Graafipure 150IU Injection in fertility treatments can increase the chances of multiple pregnancies, including twins, triplets, or higher-order multiples. This is due to the stimulation of multiple follicles and the potential release of multiple eggs. The risk of multiple pregnancies is a consideration that healthcare providers take into account when determining the dosage and monitoring the treatment.

Q5.

What is the source of Graafipure 150IU Injection?

Graafipure 150IU Injection is a highly purified mixture of two hormones called follicle-stimulating hormone (FSH) and luteinising hormone (LH). FSH and LH are natural hormones produced in both males and females. They help the reproductive organs to work normally.

Fact Box of Graafipure 150IU Injection

Molecule name: Menotrophin

 

Therapeutic class: Fertility Agent
Pharmacological class: Gonadotropins

Indications: 

Infertility in men and women 

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Introduction to endocrinology: The hypothalamic-pituitary axis, 12th edition, 2011, 1123.
  2. KD Tripathi, Essentials of Medical Pharmacology, Anterior pituitary hormonses, 7th edition, 2013, 241.
  3. Ferring Pharmaceuticals Ltd, Electronic medicines compendium (emc), [Revised on August 2019] [ Accessed on June 2023], https://www.medicines.org.uk/emc/files/pil.1294.pdf
  4. Ferring Pharmaceuticals, US Food and Drug Administration, [Revised on Feb 2014] [ Accessed on June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021663s014lbl.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Dr. Vijayalakshmi N.

Written By

Dr. Vijayalakshmi N.

BDS


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 31 Mar 2026 | 09:29 AM (IST)

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