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  3. Grafalon 100mg Injection
Quick summary
Quick Summary

Grafalon 100mg Injection

Prescription Required
Cold Chain Required
human rabbit anti-t cell immunoglobulin
Written By:Dr. Archana GuptaBDS Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:31 AM (IST)

₹31512

MRP: ₹39995

(You Save ₹8483)

1 VIAL(s) OF 5ML

Grafalon 100mg Injection is a prescription medicine used to suppress the immune system in patients undergoing organ transplantation and in certain immune related conditions. It contains anti human T lymphocyte immunoglobulin, which works by reducing the activity of T cells responsible for immune rejection. This helps prevent the body from attacking the transplanted organ. Grafalon 100mg Injection is administered under strict medical supervision in a hospital setting as part of a comprehensive transplant or immunosuppressive therapy plan.

21% OFF
Grafalon 100mg Injection
Preview
4.8 ⭐️ On Google

Grafalon 100mg Injection


Prescription Required
Required
Cold Chain Required
Cold Chain
Info

Salt Composition

HUMAN RABBIT ANTI-T CELL IMMUNOGLOBULIN

Marketer

NEOVII BIOTECH GmbH, GERMANY


Prepaid Only. Non-Returnable.

Info

21% OFF

Grafalon 100mg Injection
Preview
We are Rated 4.8 ⭐️ On Google

₹31512

MRP: ₹39,995.00

Inclusive of all taxes

21% Off

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1 Vial(s) Of 5ml

1 Vial(s) Of 5ml

₹ 31512.0/Unit

1 VIAL(s) OF 5ML


Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

HUMAN RABBIT ANTI-T CELL IMMUNOGLOBULIN

Marketer

NEOVII BIOTECH GmbH, GERMANY


Prepaid Only. Non-Returnable.

Info
Dispatch Date Icon

Dispatch: Today

Care delivered without the wait. Your order is prioritized for rapid dispatch to ensure it reaches your doorstep on time.

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Introduction to Grafalon 100mg Injection

Grafalon 100mg injection contains active components as Human rabbit anti-T cell immunoglobulin. It is a medication used to treat severe graft-versus-host disease (GvHD). In GvHD, the donor's immune cells (T cells) attack the recipient's body cells. The donor's T cells see the recipient's cells as foreign. GvHD can affect any body part, but it most commonly affects the skin, liver, gut, and lungs. If you have had a severe allergic reaction to this medication or other monoclonal antibodies, you should not receive it.  

If you have severe kidney or liver disease, Grafalon 100mg injection may worsen your condition, so it should be avoided. It can cross the blood-brain barrier and cause problems in the brain, so it should not be taken if you have active CNS disease. It may worsen your condition. It can cross the placenta and harm the fetus. If you are pregnant or breastfeeding, you should not receive it. It is generally safe for older adults and children. Still, talking to your doctor about the risks and benefits before starting Grafalon 100mg injection is important.

Uses of Grafalon 100mg Injection

Grafalon 100mg injection is used in the following: 

  • Graft-versus-host disease (GvHD)

Therapeutic Effects of Grafalon 100mg Injection

Grafalon 100mg injection depletes T cells, which are the cells that attack the body's tissues in GvHD.It does this by binding to the surface of T cells and activating the immune system to destroy them. It can also prevent T cells from developing in the first place.

Interaction of Grafalon 100mg Injection with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Grafalon 100mg injection, reducing effectiveness by causing undesirable side effects. 

More Information about Grafalon 100mg Injection

  • Stored at room temperature from 2-8°C.
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Grafalon 100mg Injection

Grafalon 100mg injection can be given by intravenous (IV) infusion or intramuscular (IM) injection. The IV route is the most common route of administration. The doctor chooses the administration route based on the patient's needs and preferences.

Safety Advice for Grafalon 100mg Injection

Breast Feeding-unsafe

Breast Feeding

Unsafe

Grafalon 100mg injection can pass into breast milk and may harm the baby, so it is safe for breastfeeding women.

Alcohol-unsafe

Alcohol

Unsafe

Alcohol can increase the risk of side effects from Grafalon 100mg injection, such as low blood counts and infections. It is safe to take alcohol while taking it.

Liver-Consult your doctor

Liver

Consult Your Doctor

Individuals with liver conditions should consult with their healthcare provider before taking Grafalon 100mg injection.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

Individuals with respiratory conditions should consult a health care provider before taking Grafalon 100mg injection.

Driving-unsafe

Driving

Unsafe

Grafalon 100mg injection can cause side effects, such as fatigue and dizziness. These side effects can affect your ability to drive. It is important to talk to your doctor about whether it is safe for you to drive while taking 

Pregnancy-unsafe

Pregnancy

Unsafe

Grafalon 100mg injection is unsafe for pregnant women as it can cross the placenta and harm the fetus.

Side Effects of Grafalon 100mg Injection

Grafalon 100mg injection causes some side effects like all medications, although not everyone will experience them. 

Serious

  • Allergic reaction
  • Low blood counts
  • Infection
  • Kidney problems
  • Liver problems
  • Pneumonitis
  • Pulmonary edema
  • Thrombosis
  • Death

Common

  • Fever
  • Chills
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Muscle pain
  • Fatigue
  • Rash
  • Itching

Word of Advice

It is important to talk to your doctor about these risks and benefits before taking Grafalon 100mg injection as it can cause low blood counts, infection, kidney problems, liver problems, pneumonitis, pulmonary edema, thrombosis, and death. It can cause low blood counts, so it is important to have your blood counts monitored regularly. This will help your doctor to identify any problems early on and take steps to correct them.  It is important to take precautions against infection as it can weaken your immune system. This includes washing your hands frequently, avoiding people who are sick, and getting vaccinated against common infections. If you experience  hives, itching, rash, shortness of breath, swelling of the face, tongue, or throat, and difficulty breathing, seek medical attention immediately.

FAQs about Grafalon 100mg Injection

Q1.

How long does  Grafalon 100mg injection treatment last?

The length of  Grafalon 100mg injection treatment depends on the condition being treated. It can range from a few days to several weeks.

Q2.

What should I do if I experience side effects from Grafalon 100mg injection?

If you experience any side effects from Grafalon 100mg injection , you should tell your doctor immediately.

Q3.

What are the long-term risks of Grafalon 100mg injection?

The long-term risks of Grafalon 100mg injection  are not well known. However, some concern is that it may increase the risk of developing autoimmune diseases.

Q4.

How long does Grafalon 100mg injection take to start working?

The time it takes for Grafalon 100mg injection  to start working varies depending on the individual. In some cases, it may start working within a few days. In other cases, it may take several weeks.

Fact Box of Grafalon 100mg Injection

Molecule name: Human rabbit anti-T cell immunoglobulin  

Therapeutic class:  Immunomodulator

Pharmacological class:  Monoclonal antibody

Indications: Graft-versus-host disease (GvHD)

References

  1. Athina L. Yoham, Damian Casadesus, [Revised on 27th May 2021] [Accessed on 13th September 2023], https://www.ncbi.nlm.nih.gov/books/NBK557884/
  2. CSL Behring GmbH, [Revised on Jun 2019] [Accessed on 13th September 2023], https://www.medicines.org.uk/emc/files/pil.6791.pdf
  3. CSL Behring (NZ) Ltd, [Revised on Jun 2021] [Accessed on  13th September 2023]https://www.medsafe.govt.nz/profs/Datasheet/r/RhDimmunoglobulinVFinj.pdf
  4. Neovii Biotech GmbH, [Revised on Jun 2019] [Accessed on 13th September 2023], https://www.hpra.ie/img/uploaded/swedocuments/448358b2-4de2-44fb-b89b-bf36f9f87182.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Dr. Archana Gupta

Written By

Dr. Archana Gupta

BDS


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 31 Mar 2026 | 09:31 AM (IST)

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