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Helidoff 25mg Tablet
Last updated on 24 Jun 2026 | 06:52 AM (IST)
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Introduction
Helidoff 25mg Tablet is an anticoagulant drug belonging to the thrombopoietin (TPO) receptor agonist category, containing the active ingredient Eltrombopag. It treats low platelet counts caused by primary immune thrombocytopenia (ITP) or hepatitis C (HCV) infection, aligning with Helidoff 25mg Tablet uses in clinical practice. ITP is an autoimmune disorder where the immune system destroys platelets, which are crucial for clotting and protecting blood vessel walls. Low platelet levels can lead to severe bleeding and bruising. This tablet is also used in adults to treat low blood counts caused by severe aplastic anemia, a condition in which the bone marrow fails to produce enough new blood cells.
This medicine should not be used in individuals with known hypersensitivity or allergic reactions to the drug or its components. Allergic reactions can range from mild to severe and may include symptoms such as rash, itching, swelling, dizziness, or difficulty breathing. Helidoff 25mg Tablet is contraindicated in patients with severe liver impairment or active liver disease. The drug can cause hepatotoxicity, as indicated by increased liver enzymes and bilirubin levels. Using this drug in individuals with severe liver disease can worsen liver function, so caution is advised. Your doctor may recommend regular eye tests to check for cataracts and bleeding in or around the retina.
If you stop taking this tablet, your blood platelet count is likely to become low again within several days. Your doctor will monitor your platelet count and adjust the dose to ensure it does not become too high, as a very high platelet count can increase the risk of blood clotting.
Do not take this tablet with dairy products or drinks, as the calcium in these items affects the absorption of the medicine. Use effective birth control during treatment, and if you become pregnant, inform your doctor. Helidoff 25mg Tablet is not advised for children under one year who have ITP, nor is it recommended for patients under 18 with low platelet counts caused by hepatitis C or severe aplastic anemia. Tell your doctor if you are taking, have recently taken, or might take other medications, including over-the-counter drugs and vitamins.
For those interested in Helidoff 25mg Tablet price, it may vary depending on your location and pharmacy. Many patients inquire about the cost during consultations. Additionally, if you're considering alternatives, Helidoff 25mg Tablet substitute options may be available. Always consult your doctor before switching medications or exploring alternatives.
Uses
Helidoff 25mg Tablet is used to treat,
Low platelet counts are caused by primary immune thrombocytopenia (ITP) or hepatitis C virus (HCV) infection.
Severe aplastic anaemia.
How Admapag 50mg Tablet Works
Helidoff 25mg Tablet stimulates megakaryocytes (the large bone marrow cells) responsible for producing platelets. By raising the number of platelets in the blood, this drug prevents bleeding and bruising.
Interaction of Helidoff 25mg Tablet with other drugs
Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications include antacid medicines, statins, ciclosporin, methotrexate, topotecan, lopinavir, or ritonavir, and vitamin and mineral supplements may interact with Helidoff 25mg Tablet and reduce effectiveness by causing undesirable side effects.
Storage conditions
Store Helidoff 25mg Tablet at room temperature (25°C).
Keep the medicine out of reach of children and pets.
How to Take Helidoff 25mg Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take an Helidoff 25mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advices
Pregnancy
Helidoff 25mg Tablet is not recommended for pregnant patients because it may cause fetal harm. You must inform your doctor if you are pregnant, suspecting, or planning to get pregnant during the treatment.
Breast Feeding
It is not known whether Helidoff 25mg Tablet passes into breast milk. If you are breastfeeding or planning to breastfeed, tell your doctor.
Lungs
It is unknown whether Helidoff 25mg Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Helidoff 25mg Tablet should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver issues before initiating the therapy.
Alcohol
It is unknown whether alcohol may interact with the Helidoff 25mg Tablet. Inform your physician if you drink alcoholic beverages.
Driving
Driving vehicles or operating heavy machinery is unsafe after taking the Helidoff 25mg Tablet. It may cause dizziness and impair concentration.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Helidoff 25mg Tablet side effects are
Common:
Nausea
Diarrhea, abdominal pain
Common cold
Cough
Respiratory tract infection
Back pain
High temperature, cough
Loss of appetite
Hair loss
Swelling in feet or hands
Headache, dizziness
Mouth and throat pain
Joint pain.
Expert tips
Avoid consuming the following 2 hours before or 4 hours after taking Helidoff 25mg Tablet: Diary Products, Antacids, Supplements containing iron and aluminium
If you miss a dose, take the next dose at the usual scheduled time.
Do not take more than one dose per day.
Do not stop taking Helidoff 25mg Tablet without consulting your doctor.
If your doctor discontinues the treatment, your platelet count will be monitored weekly for four weeks.
If you have any doubts or questions about how to take this medicine, consult your doctor for guidance.
FAQs
Q1.
What is ITP?
Immune thrombocytopenia, also known as ITP, is a rare blood disorder. People with ITP have insufficient platelets in their blood. A low platelet count can cause bruising and bleeding.
Q2.
Who should not use Helidoff 25mg Tablet?
People with immune (primary thrombocytopenia (ITP) and children under one should not use Helidoff 25mg Tablet. It is also not suggested for people with severe aplastic anemia and hepatitis C.
Q3.
Will you be monitored during treatment with Helidoff 25mg Tablet?
Yes, you will be monitored during tablet. Your healthcare provider will regularly access your white blood cell, platelets, blood clotting factors, heart rate, eye test, and complete blood count.
Q4.
Is it safe to take Helidoff 25mg Tablet on an empty stomach?
Yes, Helidoff 25mg Tablet should be taken on an empty stomach. Because antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminum, selenium, and zinc), dairy products, calcium-enriched foods, and fortified juices interfere with this drug absorption. So, please take them at least two hours before or four hours after taking the medication.
Q5.
What happens if you discontinue using Helidoff 25mg Tablet?
If you discontinue using Ltromb Tablet suddenly, it decreases platelet count as it can lead to severe bleeding. However, telling your healthcare practitioner before discontinuing this medication is advisable.
Q6.
What are the storage conditions for Helidoff 25mg Tablet?
This tablet at 25°C and out of the reach of children. After the expiration date, do not use this medication.
Fact Box
Molecule name | Eltrombopag |
Therapeutic class | Anticoagulant |
Pharmacological class | Thrombopoietin (TPO) receptor agonist |
Indications | 1. Low platelet counts caused by immune primary thrombocytopenia (ITP) or hepatitis C virus (HCV) infection. 2. Severe aplastic anaemia. |
References
Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [Accessed on 22 May 2023], https://www.medicines.org.uk/emc/files/pil.508.pdf
GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [Accessed on 22 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
Revolade, Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/revolade-epar-product-information_en.pdf [Accessed on 22 May 2023].
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 24 Jun 2026 | 06:52 AM (IST)
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