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Hetronifly 100mg Solution for Infusion

Prescription Required
serplulimab

₹19411

MRP: ₹23437

(You Save ₹4026)

1 VIAL(s)

17% OFF
Hetronifly 100mg Solution for Infusion
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₹19411

MRP: ₹23,437.00

Inclusive of all taxes

17% Off

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1 Vial(s)

1 Vial(s)

₹ 19411.0/Unit
Prescription Required
Prescription Required

Salt Composition

SERPLULIMAB

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INTAS PHARMACEUTICALS LTD

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Introduction

Hetronifly 100mg Solution for Infusion contains Serplulimab, a monoclonal antibody classified under immunotherapy medicines known as PD-1 (Programmed Death-1) inhibitors. It is used in the treatment of certain advanced cancers by strengthening the body’s immune response against tumour cells.

Cancer cells often escape immune detection by blocking immune checkpoint pathways. Serplulimab works by targeting the PD-1 receptor on immune cells, helping the body recognise and destroy cancer cells more effectively.

During treatment, doctors may recommend regular blood tests, organ function monitoring, and imaging scans to assess response and safety. Since this medicine affects the immune system, careful observation for immune-related side effects is essential throughout therapy.

Uses

Hetronifly 100mg Solution for Infusion is used for the treatment of:

• Certain advanced or metastatic cancers as advised by oncologists.
• Cancers that respond to immune checkpoint inhibitor therapy.
• Tumours that have progressed after standard treatments.

How Hetronifly 100mg Works

Hetronifly works by activating the body’s immune defence against cancer cells.

It helps by:

• Blocking PD-1 receptors that suppress immune response
• Allowing immune cells to recognise cancer cells
• Enhancing destruction of tumour cells
• Slowing cancer progression

This restores the immune system’s natural ability to fight cancer.

Interaction with Other Medications

Inform your doctor about all medicines you take, including supplements.

Important interactions may occur with:

• Immunosuppressive medicines
• Steroids (long-term use)
• Certain chemotherapy drugs
• Autoimmune disorder treatments

These may affect effectiveness or increase side effects.

Storage Conditions

• Store as per hospital or pharmacy instructions (usually refrigerated).
• Protect from light.
• Do not freeze.
• Keep out of reach of children.
• Do not use after expiry.

How To Take Hetronifly 100mg

• Administered as an intravenous infusion.
• Given in hospital or oncology clinic.
• Dose and schedule determined by doctor.
• Infusion usually takes about 30 to 60 minutes.

Safety Advices

Pregnancy-Unsafe

Pregnancy

Unsafe

May harm the unborn baby. Effective contraception is required.

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

Not recommended during treatment.

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Monitor Especially in long-term therapy.

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Regular liver function tests required.

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

The interaction between Hetronifly and alcohol is not clearly established. Alcohol may worsen side effects such as fatigue, nausea, liver strain, and immune-related reactions.

Driving-Consult Your Doctor

Driving

Consult Your Doctor

Fatigue or dizziness may occur.

Side Effects

Like all immunotherapy medicines, Hetronifly may cause immune-related reactions.

Common Side Effects

 • Fatigue
• Fever
• Skin rash or itching
• Nausea
• Loss of appetite
• Muscle or joint pain
• Diarrhoea

Serious Side Effects

 • Lung inflammation (shortness of breath, cough)
• Liver problems (yellowing of skin, dark urine)
• Severe diarrhoea or colitis
• Hormone gland disorders
• Severe allergic reactions

Seek medical help immediately if severe symptoms appear.

Expert Tips

 • Attend all scheduled infusions and follow-ups.
• Report new symptoms early, even mild ones.
• Stay hydrated and eat balanced meals.
• Avoid self-medication during treatment.
• Keep regular blood test appointments.
• Inform all doctors you are on immunotherapy.

FAQs

Q1.

What is Hetronifly 100mg used for?

Hetronifly is used in cancer treatment as an immunotherapy medicine that helps the immune system fight tumour cells more effectively.

Q2.

Is Hetronifly chemotherapy?

No. It is immunotherapy, which works differently by activating the immune system rather than directly killing cancer cells.

Q3.

How often is Hetronifly given?

The schedule depends on cancer type and treatment plan, usually every few weeks as an IV infusion.

Q4.

What tests are needed during treatment?

Blood tests, liver and kidney function tests, hormone levels, and imaging scans are commonly monitored.

Q5.

When should I seek urgent help?

Seek immediate care for breathing problems, severe diarrhoea, high fever, yellow skin, or allergic reactions.

Fact Box

Molecule Name

Serplulimab

Therapeutic Class

Anticancer immunotherapy

Pharmacological Class

PD-1 inhibitor (monoclonal antibody)

Indications

Advanced cancers responsive to immune checkpoint therapy.

References 

  1. Xu J, Zhang Y, Jia R, et al. Anti-PD-1 antibody Serplulimab in patients with advanced solid tumours: safety, pharmacokinetics, and preliminary efficacy. Clinical Cancer Research. 2021;27(18):5163–5172.

  2. Chinese Society of Clinical Oncology. Immune checkpoint inhibitors in oncology practice: clinical guidance and monitoring. CSCO Guidelines. 2022.

  3. U.S. National Library of Medicine. Serplulimab (anti-PD-1 monoclonal antibody) clinical trial data. ClinicalTrials.gov. https://clinicaltrials.gov

  4. Tang B, Yan X, Sheng X, et al. Efficacy and safety of Serplulimab in advanced malignancies: emerging immunotherapy evidence. Journal of Immunotherapy. 2022;45(6):245–253.

  5. National Cancer Institute. Immune checkpoint inhibitors and cancer treatment overview. https://www.cancer.gov

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Dr. Vikas B S

Written By

Dr. Vikas B S

Pharm D

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 26 Sep 2026 | 08:41 AM (IST)

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