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Hylasto ONE Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹4137
MRP: ₹6696
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1 PREFILLED SYRINGE(s) OF 6ML
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MRP: ₹6,696.00
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Introduction to Hylasto ONE Injection
Hylasto One injection contains an active ingredient called Sodium Hyaluronate, which belongs to the group of medicines called intra-articular agents. It is like the natural fluid that cushions your joints, which helps lubricate and protect your joints, acting as a shock absorber. This medicine relieves knee pain in patients with osteoarthritis (OA). It is usually given to patients who have not responded well to the other arthritis medications.
Do not use Hylasto One injection if you are allergic to Sodium Hyaluronate or any of its ingredients. Do not use this medication if you have an infection in your knee or in the skin around your knee. Before taking the medicine, notify your doctor if you have had a history of blood clots or circulation issues in your legs or if you have an allergy to birds, feathers, or egg products. Report to your doctor if you have pre-existing chondrocalcinosis (cartilage calcification). Not recommended for children aged 21 years and younger as its safety and effectiveness have not been proven.
Before start taking Hylasto One injection, inform your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Notify your doctor if you have a history of any disease. The common side effects of the medicine are pain, redness, stiffness, bruising, or puffiness at the injection site, nausea, stomach pain, trouble walking, back pain, joint pain, muscle pain, numbness or tingling, headache, dizziness, and a runny or stuffy nose.
Uses of Hylasto ONE Injection
- Treatment for osteoarthritis
Therapeutic Effects of Hylasto ONE Injection
Hylasto One injection works by providing extra lubrication and cushioning to the knee joint affected by osteoarthritis. It helps reduce friction and protect the joint, which can ease pain and improve movement. The injection replenishes the natural fluid in the joint, providing relief and support for better knee function.
Interaction of Hylasto ONE Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Hylasto One injection and can cause undesirable side effects.
More Information about Hylasto ONE Injection
- Keep out of sight and reach of pets and children.
- Store at 2°‐25°C.
- Protect it from light.
- Do not freeze the medicine.
- Always check the expiry date before consuming it.
How to consume Hylasto ONE Injection
Hylasto One injection will be administered to you by a healthcare professional in a hospital setting. Do not self-administer. It is usually administered into the knee joint. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advice for Hylasto ONE Injection
Breast Feeding
It is unknown whether Hylasto One injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
Alcohol
It is unknown whether consuming alcohol while taking Hylasto One injection is safe. Please speak with your physician.
Liver
Limited information is available on the use of Hylasto One injection in patients with liver disease. Therefore, it is crucial to consult your doctor before considering its usage to ensure it is safe and appropriate for your condition.
Lungs
It is unknown whether Hylasto One injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
It is unknown whether Hylasto One injection alters driving ability. However, if you experience side effects like tiredness or drowsiness, avoid driving and using machines.
Pregnancy
It is unknown whether Hylasto One injection is harmful to the unborn baby. Before starting the treatment, inform your doctor if you are pregnant or planning to get pregnant or think you may be pregnant.
Side Effects of Hylasto ONE Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe pain or swelling around the knee
Common
- Pain, redness, stiffness, bruising, or puffiness at the injection site
- Nausea
- Stomach pain
- Trouble walking
- Back pain
- Joint pain
- Muscle pain
- Numbness or tingly feeling
- Headache
- Dizziness
- Runny or stuffy nose
Word of Advice
Avoid using skin disinfectants that contain quaternary ammonium salts or chlorhexidine along with Hylasto One injection, as it may cause hyaluronan to form clumps. After intra-articular injection, avoid strenuous activities and prolonged weight-bearing activities (over an hour) for 48 hours as part of the treatment.
Do not stop the medicine until your doctor advises. Do not breastfeed while taking Hylasto One injection unless doctor advise. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
FAQs about Hylasto ONE Injection
Q1.
Can I use Hylasto One injection if I’m pregnant?
Consult your medical professional regarding the use of Hylasto One injection during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q2.
What is Hylasto One injection?
Hylasto One injection is like the natural fluid that cushions your joints, which helps lubricate and protect your joints, acting as a shock absorber.
Q3.
Can I use Hylasto One injection with other medications?
Before using Hylasto One injection, it is essential to consult your doctor, as they can interact with various other medications. Talking to your doctor will help to ensure the safety and appropriate use of the medicine with your current medication regimen.
Q4.
What is the use of Hylasto One injection?
Hylasto One injection is used to relieve knee pain in patients with osteoarthritis (OA). It is usually given to patients who have not responded well to the other arthritis medications.
Q5.
Can I drive after taking Hylasto One injection?
It is unclear whether Hylasto One injection affects driving ability. To understand its safety and efficacy while driving, consult your doctor.
Fact Box of Hylasto ONE Injection
| Molecule Name: Sodium Hyaluronate | Therapeutic class: Rheumatologics |
| Pharmacological class: Intra-Articular Agents | Indications: Treatment for osteoarthritis |
References
- Hanmi Pharm Co., Ltd; Sodium Hyaluronate; Product information; https://www.accessdata.fda.gov/cdrh_docs/pdf17/P170016D.pdf
- Fidia Pharma USA, Inc, US Food and Drug Administration, [Revised on 2019] [ Accessed on 20th July 2023], https://www.accessdata.fda.gov/cdrh_docs/pdf18/P180040D.pdf
- Roy Altman et al; Efficacy and safety of repeated courses of Sodium hyaluronate injections for knee osteoarthritis: A systematic review; Published on Oct 2018; Accessed on 19/07/2021; https://pubmed.ncbi.nlm.nih.gov/29496227/
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Aswini Priya Velmurugan
PG in Biotechnology

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)

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