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Ibrumed 140mg Capsule
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹4650
MRP: ₹9112.5
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30 CAPSULE(s) IN A BOTTLE
Ibrumed 140mg Capsule contains ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor used in the treatment of blood cancers like chronic lymphocytic leukemia and mantle cell lymphoma. It works by blocking signals that help cancer cells survive and multiply. The capsule is taken orally as prescribed by a physician.
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Introduction to Ibrumed 140mg Capsule
Ibrumed140 mg Capsule consists of the active ingredient Ibrutinib. It is indicated to treat blood cancers such as mantle cell lymphoma (MCL), chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (CLL), Waldenstrom’s macroglobulinemia, and Marginal zone lymphoma (MZL). These are cancers of the white blood cells called lymphocytes that are part of the immune system. They differ from each other by the location where cancer occurs, type of lymphocytes affected, and certain other factors.
Ibrumed140 mg capsule is also used to treat chronic graft versus host disease (cGVHD) after the failure of systemic therapy. During allogeneic stem cell transplantation, the patient receives stem cells from the donor. GVHD occurs when donor cells view the patient’s cells as foreign and attack them. Before taking this medicine , you need to talk with your physician if you have bleeding problems, infection, liver problems, heart problems, or intolerance to some sugars. This medication is not recommended for adolescents and children.
It is vital to let the physician know if you have recently had or are about to have any surgical procedure. Your physician may stop Ibrumed140 mg Capsule for any planned surgical or medical procedure. Use effective birth control during the treatment and for at least one month after the final dose. Avoid having grapefruit or oranges in any form during this treatment; they may raise the amount of drug in the blood. Drink plenty of fluid to prevent dehydration. Inform your physician if you have diarrhea that does not go away.
Uses of Ibrumed 140mg Capsule
- Mantle cell lymphoma
- Chronic lymphocytic leukemia (Blood cancer)
- Small lymphocytic lymphoma
- Waldenstrom’s macroglobulinemia
- Chronic graft vs. host disease after failure of systemic therapy
Therapeutic Effects of Ibrumed 140mg Capsule
The mechanism of action of Ibrumed 140 mg involves blocking a specific protein called Bruton's tyrosine kinase (BTK) which plays a key role in the survival and growth of cancer cells. By inhibiting BTK, Ibrumed 140 mg prevents the cancer cells from receiving the signals they need to grow and divide, leading to their eventual death.
Interaction of Ibrumed 140mg Capsule with other drugs
Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interacting with Ibrumed140mg , may reduce effectiveness by causing undesirable side effects.
More Information about Ibrumed 140mg Capsule
- Store the capsules in the original packaging at room temperature (20-25°C).
How to consume Ibrumed 140mg Capsule
Consume this medicine at the same time each day. While taking Ibrumed 140 mg capsule, do not consume grapefruit or orange in any form during the treatment. Drink plenty of fluid to prevent dehydration.
Safety Advice for Ibrumed 140mg Capsule
Breast Feeding
Do not breastfeed while you are under Ibrumed 140 mg capsule and for at least one week after the last dose. Consult your physician for risks and benefits.
Alcohol
It is unknown whether it is safe to consume alcohol with the Ibrumed 140 mg capsule. Please consult your doctor.
Liver
Inform your physician before starting this treatment if you have liver problems, including hepatitis B infection. Ibrumed 140 mg capsule could cause the reactivation of the hepatitis B virus, which makes the condition fatal.
Lungs
Ibrutinib capsule may cause interstitial lung disease. So if you have any respiratory disorder, inform your doctor before starting the treatment.
Driving
Ibrutinib capsule may cause dizziness or tiredness. Avoid driving or operating machines if you feel dizzy or tired.
Pregnancy
This medicine can harm the unborn baby. Do not take Ibrumed 140 mg Capsule unless your physician instructs you to take it. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant.
Side Effects of Ibrumed 140mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Bleeding problems
- Infections
- Decrease in blood cell counts.
- Heart problems
- High BP
- Secondary cancer
- Tumor lysis syndrome
- Severe allergic reactions
Common:
- Nausea, vomiting, diarrhea
- Tiredness
- Muscle and bone pain
- Rash and bruising
- Mouth sores
- Pneumonia
- Fever, chills
- Breathlessness
- Constipation
- Dizziness
- Body pain
- Swollen ankles and feet
- Increased creatinine levels in blood
- Heavier periods and blood in urine
- Blurred vision
- Weakness and numbness
Word of Advice
Contact your doctor immediately if you experience bleeding, infection, shortness of breath, or chest discomfort. Report to your doctor if you have had a history of heart failure or hepatitis infection. It is not recommended to take this medicine before or after surgery as it causes a delay in wound healing. Discuss effective contraceptive options with your healthcare provider and use them during treatment and for a month after the last dose of Ibrumed140mg.
FAQs about Ibrumed 140mg Capsule
Q1.
What is the correct way to take Ibrumed 140 mg?
Ibrutinib is taken orally as a capsule, usually once a day with a glass of water. It also depends on your frequency. It is better to take it at the fixed time. Avoid having grapefruit or oranges in any form during this treatment; they may raise the amount of drug in the blood and follow the instructions of your doctor.
Q2.
Can Ibrumed 140 mg be taken with other medications?
Ibrutinib can interact with other medications, so it is important to inform your doctor of all medications you are taking, including prescription, over the counter, and herbal supplements.
Q3.
Can I drink alcohol while taking Ibrumed 140 mg?
Alcohol consumption should be avoided while taking Ibrumed 140 mg, as it may increase the risk of certain side effects, such as liver damage. You should talk to your doctor about any concerns you have regarding alcohol use.
Q4.
Can Ibrumed 140 mg cure all types of cancer?
Ibrutinib has been shown to be effective in treating certain types of blood cancers, but its efficacy in other types of cancer is still being studied. It is important to remember that cancer is a complex disease with many different causes and factors, and there is no single cure that works for all types of cancer. If you have been diagnosed with cancer, it is important to work with your doctor to determine the best treatment options for your specific case.
Q5.
Should I use contraception while under this Ibrumed 140 mg capsule?
Yes, It is necessary to use contraception during and even after the last dose of Ibrumed 140 mg capsule. Inform your doctor if you are pregnant or think you might be or if you are planning to get pregnant.
Fact Box of Ibrumed 140mg Capsule
Molecule name: Ibrutinib | Therapeutic class: Anti Neo plastics |
pharmacological class: Bruton's tyrosine kinase (BTK) inhibitors
| Indications:
|
References
- Janssen-Cilag International Ltd, Electronic Medicines Compendium (EMC), [Revised on Dec 2021] [Accessed on 18th March 2023], https://www.medicines.org.uk/emc/files/pil.10040.pdf
- Janssen Biotech, Inc, US Food and Drug Administration, [Revised on May 2022] [ 18th March 2023], https://www.Bdbrut.com/files/prescribing-information.pdf
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056.
- Sapna Parmar, Khilna Patel, Javier Pinilla-Ibarz, Ibrutinib (Bdbrut): A Novel Targeted Therapy for Chronic Lymphocytic Leukemia, Drug Forecast, Published on July 2014; Accessed on 18th March 2023]; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103574/pdf/ptj3907483.pdf
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Author Details
Written By
Aswini Priya Velmurugan
PG in Biotechnology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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