Quick Summary
Ifosma 1000mg Injection
Last updated on 30 Jun 2026 | 07:05 AM (IST)
₹332
MRP: ₹443
(You Save ₹111)
1 VIAL(s)
25% OFF
₹332
MRP: ₹443.00
Inclusive of all taxes
25% Off
Dispatch: Today
Order In: 0h 0m 0s
0h 0m 0s
Order before timer ends to ensure your medicine is dispatched at...
Substitutes
Ifozee 1gm Injection
ZEE LABORATORIE...
₹ 268.00/injection
19% cheaper
Ifex-M 1gm Injection
ZYDUS CADILA
₹ 341.00/injection
3% costlier
Ifoneon 1gm Injection
NEON LABORATORI...
₹ 342.00/injection
4% costlier
Ipoget With Mesna 1gm Injection
GLS PHARMA LTD
₹ 351.00/injection
6% costlier
Introduction to Ifosma 1000mg Injection
Ifosma 1000mg Injection is an anticancer and cytoprotective drug belonging to the category of alkylating agents and hemorrhagic cystitis inhibitor, containing the active ingredient Ifosfamide and Mesna. These drugs are indicated for the treatment of bladder inflammation and cancers in the soft tissues, germ cell, pancreas and cervix. Mesna mainly protects against some of the harmful effects of certain chemotherapy medications.
If you had an allergic reaction to this drug or any of its components, it should not be used. This medicine may cause severe bone marrow suppression which results in low white blood cell count or low platelet count due to chemotherapy or radiation therapy. You should wait for three months before starting the treatment with this drug, if you have received a live virus vaccine such as measles, mumps, rubella, or chickenpox. It is advised to use this drug with caution in severe kidney or liver diseased individuals. Talk to your doctor if you take any other medications or before using over-the-counter medicines or herbal products. Your doctor will evaluate the risk of interaction with this medication. Consult your doctor before using this medication if you are pregnant or plan to have a baby. Ifosma 1000mg Injection are unsafe to use during pregnancy as it causes harm to an unborn fetus. Your health care practitioner will conduct a pregnancy test before you start treatment with Ifosma 1000mg Injection. Discuss with your doctor effective birth control methods and utilise them for at least two weeks following the last dose. Breastfeeding should be avoided during the treatment with this drug as it may pass into breast milk in small amounts.
Uses of Ifosma 1000mg Injection
- Hemorrhagic cystitis (bladder inflammation)
- Soft tissue cancer
- Germ cell cancer
- Pancreatic cancer
- Cervical cancer
Therapeutic Effects of Ifosma 1000mg Injection
These two combinations together work by damaging the DNA in cancer cells, which leads to cell death and slows the growth and spread of cancer. Mostly, this involves the formation of reactive metabolites in the liver, which are then transported to cancer cells in the body. These metabolites react with the DNA in the cancer cells, causing cross-links and breaks in the DNA strands. This interferes with the replication and transcription of DNA, leading to cell death.
Interaction of Ifosma 1000mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Ifosma 1000mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Ifosma 1000mg Injection
- Store Ifosma 1000mg Injection in a refrigerator (20°C to 25°C).
- Do not freeze.
- Keep it out of reach from children.
How to consume Ifosma 1000mg Injection
It will be given to you by a doctor or nurse in a hospital or clinic setting trained in cancer chemotherapy. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Safety Advice for Ifosma 1000mg Injection
Breast Feeding
Ifosma 1000mg Injection is not recommended in breastfeeding women as it may pass into the breast milk.
Alcohol
It is unknown whether consuming alcohol interacts with the Ifosma 1000mg Injection. Please consult your doctor for more advice.
Liver
It is unknown whether Ifosma 1000mg Injection can be used for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Lungs
It is unknown whether Ifosma 1000mg Injection can be used for patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking the Ifosma 1000mg Injection.
Pregnancy
Ifosma 1000mg Injection is unsafe for pregnant women as it may harm the unborn baby. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 3 months after your last dose is necessary.
Side Effects of Ifosma 1000mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Immune system suppression
- Low levels of RBC, WBC and platelets in the blood
- Bone marrow suppression
- Nerve toxicity
- Urinary problems
- Lung problems
- Kidney problem
- Rash
- Hypersensitivity reactions
Common
- Hair loss
- Fever
- Phlebitis
- Liver toxicity
- Infections
Word of Advice
This injection may cause severe birth defects if taken during pregnancy. Female patients with reproductive potential should use effective contraception during the treatment. Male patients with female partners with reproductive potential should use effective birth control methods during the treatment and for at least 5 months after their last dose. Do not breastfeed during treatment with this injection. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy. Ifosma 1000mg Injection may cause dizziness, drowsiness, or blurred vision, so it is important to avoid driving. It's important to avoid consuming grapefruit or grapefruit juice while taking this injection because this can lead to increased levels of the drug in your body and a higher risk of side effects. If you miss a dose of Ifosma 1000mg Injection and it is close to the time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule. It is not recommended to take a double dose to make up for a missed one.
FAQs about Ifosma 1000mg Injection
Q1.
How is Ifosma 1000mg Injection administered?
Ifosma 1000mg Injection is usually administered as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.
Q2.
What happens if I miss my Ifosma 1000mg Injection?
If you miss a dose of Ifosma 1000mg Injection and it is close to the time for your next scheduled dose, you should skip the missed dose and continue with your regular dosing schedule. It is not recommended to take a double dose to make up for a missed one.
Q3.
What is the purpose of Ifosma 1000mg Injection?
Ifosma 1000mg Injection is often used in combination with other chemotherapy drugs to increase its effectiveness. It may also be used before surgery to shrink the tumour or after surgery to kill any remaining cancer cells.
Q4.
Can Ifosma 1000mg Injection be given during pregnancy?
No, Ifosma 1000mg Injection can cause harm to a developing fetus and should not be given during pregnancy.
Q5.
Who should not use Ifosma 1000mg Injection?
Ifosma 1000mg Injection is not recommended for people who are allergic to this drug, or any of its ingredients. Also, women who are pregnant or breastfeeding should avoid taking it, because this medicine can harm an unborn baby or pass into breast milk.
Q6.
What should I avoid while taking Ifosma 1000mg Injection?
It is recommended to quit smoking or limit tobacco use while taking this medication. Smoking may also worsen some of the side effects of Ifosma 1000mg Injection, such as the risk of liver toxicity.
Fact Box of Ifosma 1000mg Injection
Molecule name: Ifosfamide + Mesna | Therapeutic class: Anticancer + Cytoprotectants |
Pharmacological class: 1.Ifosfamide-Alkylating agents 2.Mesna-Hemorrhagic cystitis inhibitor | Indications: 1.Hemorrhagic cystitis (bladder inflammation) 2.Soft tissue cancer 3.Germ cell cancer 4.Pancreatic cancer 5.Cervical cancer |
References
- Baxter Corporation, [Revised on 27th Jun 2018] [Accessed on 10th Aug 2021], https://www.baxter.ca/sites/g/files/ebysai1431/files/2018-11/Ifex_EN.pdf
- Teva Parenteral Medicines, Inc., [Revised on Feb 2020] [Accessed on 17th Dec 2021], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=14f535d7-4593-4cee-94fb-54ee239d95d2&type=display
- Boehringer-Ingelheim, Mesna [Revised on March 2014] [ Accessed on 06 April 2023], https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Ben%20Venue_Bedford%20Labs/55390-045-01%20MSN%201G/5539004501
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
- Bertram.G.Katzung, Basic and Clinical Pharmacology, Cancer Chemotherapy, 14th edition, 2017, 953.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
Did you find this information helpful?
Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 30 Jun 2026 | 07:05 AM (IST)
Want to know more?
Read Our Editorial Policy
