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Imalieva 400mg Tablet
Prescription Required
Salt Composition : Imatinib
Manufacturer : Allieva Pharma Pvt. Ltd.
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Imalieva 400mg Tablet
Imalieva 400mg Tablet contains the active ingredient called Imatinib. It is an antineoplastic drug that belongs to the class of tyrosine kinase inhibitors. This tablet is used in treating adults and children with chronic myeloid leukemia (CML is a form of leukemia in which certain abnormal white blood cells start growing out of control) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL). It is also used to treat myelodysplastic/myeloproliferative diseases (abnormal growth of blood cells), Hypereosinophilic syndrome and chronic eosinophilic leukemia (blood disease), gastrointestinal stromal tumors (stomach and bowel cancer) and dermatofibrosarcoma protuberans (cancer in the tissue beneath the skin).
Do not take Imalieva 400mg Tablet if you are allergic to Imatinib or any other ingredients of this medicine. Before initiating the treatment, inform your physician if you have kidney, heart, or liver problems, if you have thyroid problems, or if your thyroid gland has been removed. Notify your doctor if you ever had or have a hepatitis B infection because this medicine could cause the hepatitis B to become active again. Report any bruising, bleeding, fever, fatigue, and confusion symptoms when taking this medicine. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Uses of Imalieva 400mg Tablet
- Chronic myeloid leukemia (CML)
- Philadelphia chromosome-positive acute lymphoblastic leukemia (ph-positive ALL)
- Myelodysplastic/myeloproliferative diseases (MDS/MPD)
- Hypereosinophilic syndrome (HES)
- Chronic eosinophilic leukemia (CEL)
- Dermatofibrosarcoma protuberans (DFSP)
- Gastrointestinal stromal tumors (GIST)
Therapeutic Effects of Imalieva 400mg Tablet
Imalieva 400mg Tablet is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply. It inhibits the multiplication and induces cell death in abnormal cancer cells.
Interaction of Imalieva 400mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Imalieva 400mg Tablet and reduce its effectiveness by causing undesirable side effects. Inform your physician, especially if you are using medicines that prevent the formation of blood clots.
More Information about Imalieva 400mg Tablet
- Store Imalieva 400mg Tablet at the room temperature (25°C)
- keep the injection away from the reach of children and pets.
- Do not freeze.
- Keep the injection away from children and pets' reach.
How to consume Imalieva 400mg Tablet
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity and other factors. Take the tablets as prescribed by your doctor. Do not break, crush, or chew the tablets. Swallow the tablet whole with a glass of water. Take this medicine with a meal to avoid stomach problems. If you are unable to swallow the tablets, you can dissolve them as per your doctor's advice.
Safety Advices for Imalieva 400mg Tablet
Pregnancy
Imalieva 400mg Tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Tag: unsafe
Breastfeeding:
Breast Feeding
Breastfeeding is not recommended in patients taking Imalieva 400mg Tablet because the medicine passes into the breast milk in small amounts and may harm your baby.
Tag: unsafe
Lungs
It is unknown whether Imalieva 400mg Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unsafe to use in patients with liver disease like hepatitis or a history of hepatitis. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unknown whether it is safe to consume alcohol when taking an Imalieva 400mg Tablet. Consult your doctor for more advice.
Driving
It is unsafe to drive or operate heavy machinery after taking an Imalieva 400mg Tablet because you may feel dizzy, drowsy or get blurred vision.
Side Effects of Imalieva 400mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Swelling in the face, legs, ankle and feet
- Bruising
- Nausea
- Vomiting
- Weight gain
- Disturbed sense of taste
- Feeling dizzy or weak
- Eye problem (discharging, itching, redness or swelling)
- Nose bleeds
- Itching
- Unusual hair loss
- Muscle cramps and pain
- Diarrhea
- Numbness (hands or feet)
- Mouth ulcers.
- Joint pain with swelling.
- Dryness (eye, mouth and skin)
- Decreased or increased skin sensitivity.
- Hot flushes, chills or night sweats.
- Tiredness or dizziness
- Abdominal pain
- Headache
Serious:
- Heart problem
- Lung or respiratory problem
- Blood disorder
- Chronic renal failure
- Retarding of growth in children
- GI disorders
- Hypothyroidism
- Liver failure
- Swelling in the body
Word of Advice
It is recommended to drink a sufficient amount of water or electrolyte to compensate for the water loss during the diarrhoea or vomiting. It is recommended to take enough rest for a fast recovery. It is advised to avoid eating junk and oily foods which worsen the adverse effect of the drug. Your doctor will advise you to do a blood test and weight check during the medication. Applying a small amount of honey in the mouth ulcer, it will help you to relieve the pain caused by the ulcer.
FAQs
Q 1. When is the best time to take an Imalieva 400mg Tablet?
Take the tablet as prescribed by your doctor. Take an Imalieva 400mg Tablet at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.
Q 2. Can I take an Imalieva 400mg Tablet if I have hepatitis B or a history of hepatitis B infection?
It is recommended to speak with your doctor if you have hepatitis B or a history of hepatitis B infection. This medicine can increase the risk of hepatitis B in individuals.
Q 3. Can I take an Imalieva 400mg Tablet if I am pregnant?
Imalieva 400mg Tablet is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Fact Box of Imalieva 400mg Tablet
Molecule name: Imatinib | Therapeutic class: Antineoplastics |
Pharmacological class: Tyrosine kinase inhibitor | Indications:
|
Dosage form: Tablet | Habit form: No forming |
References
- Cipla (EU) Limited, Electronic Medicine Compendium (EMC), [Revised on Dec 2023], [Accessed on Mar 2024], https://www.medicines.org.uk/emc/files/pil.10133.pdf
- Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [Revised on Sep 2016], [Accessed on Mar 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021588s047lbl.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Disclaimer
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