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Imatinate 100mg Capsule
Prescription Required
Salt Composition : Imatinib
Manufacturer : KHANDELWAL LABORATORIES PVT LTD
Origin of Medicine : India
30 Capsule(s) In A Bottle
Introduction to Imatinate 100mg Capsule
Imatinate 100mg Capsule contains the active ingredient called Imatinib. It is an antineoplastic drug that belongs to the class of tyrosine kinase inhibitors. This capsule is used in treating adults and children with chronic myeloid leukemia (CML is a form of leukemia in which certain abnormal white blood cells start growing out of control) and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL). It is also used to treat myelodysplastic/myeloproliferative diseases (abnormal growth of blood cells), Hypereosinophilic syndrome and chronic eosinophilic leukemia (blood disease), gastrointestinal stromal tumors (stomach and bowel cancer) and dermatofibrosarcoma protuberans (cancer in the tissue beneath the skin).
Do not take Imatinate 100mg Capsule if you are allergic to Imatinib or any other ingredients of this medicine. Before initiating the treatment, inform your physician if you have kidney, heart, or liver problems, if you have thyroid problems, or if your thyroid gland has been removed. Notify your doctor if you ever had or have a hepatitis B infection because this medicine could cause the hepatitis B to become active again. Report any bruising, bleeding, fever, fatigue, and confusion symptoms when taking this medicine. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding.
Uses of Imatinate 100mg Capsule
- Chronic myeloid leukemia (CML)
- Philadelphia chromosome-positive acute lymphoblastic leukemia (ph-positive ALL)
- Myelodysplastic/myeloproliferative diseases (MDS/MPD)
- Hypereosinophilic syndrome (HES)
- Chronic eosinophilic leukemia (CEL)
- Dermatofibrosarcoma protuberans (DFSP)
- Gastrointestinal stromal tumors (GIST)
Therapeutic Effects of Imatinate 100mg Capsule
Imatinate 100mg Capsule is a protein-tyrosine kinase inhibitor that blocks a specific abnormal protein created by a chromosomal abnormality that signals cancer cells to multiply. It inhibits the multiplication and induces cell death in abnormal cancer cells.
Interaction of Imatinate 100mg Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Imatinate 100mg Capsule and reduce its effectiveness by causing undesirable side effects. Inform your physician, especially if you are using medicines that prevent the formation of blood clots.
More Information about Imatinate 100mg Capsule
- Store Imatinate 100mg Capsule at the room temperature (25°C)
- keep it away from the reach of children and pets.
- Do not freeze.
- Keep it away from children and pets' reach.
- Protect it from light.
How to consume Imatinate 100mg Capsule
Your doctor will decide the dose and duration of the treatment based on your disease condition, severity and other factors. Take the capsules as prescribed by your doctor. Do not break, crush, or chew the capsules. Swallow the capsule whole with a glass of water. Take this medicine with a meal to avoid stomach problems. If you are unable to swallow the capsules, you can dissolve them as per your doctor's advice.
Safety Advices for Imatinate 100mg Capsule
Pregnancy
Imatinate 100mg Capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Breast Feeding
Imatinate 100mg Capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Lungs
It is unknown whether Imatinate 100mg Capsule can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unsafe to use in patients with liver disease like hepatitis or a history of hepatitis. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unknown whether it is safe to consume alcohol when taking an Imatinate 100mg Capsule. Consult your doctor for more advice.
Driving
It is unsafe to drive or operate heavy machinery after taking an Imatinate 100mg Capsule because you may feel dizzy, drowsy or get blurred vision.
Side Effects of Imatinate 100mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common:
- Swelling in the face, legs, ankle and feet
- Bruising
- Nausea
- Vomiting
- Weight gain
- Disturbed sense of taste
- Feeling dizzy or weak
- Eye problem (discharging, itching, redness or swelling)
- Nose bleeds
- Itching
- Unusual hair loss
- Muscle cramps and pain
- Diarrhea
- Numbness (hands or feet)
- Mouth ulcers.
- Joint pain with swelling.
- Dryness (eye, mouth and skin)
- Decreased or increased skin sensitivity.
- Hot flushes, chills or night sweats.
- Tiredness or dizziness
- Abdominal pain
- Headache
Serious:
- Heart problem
- Lung or respiratory problem
- Blood disorder
- Chronic renal failure
- Retarding of growth in children
- GI disorders
- Hypothyroidism
- Liver failure
- Swelling in the body
Word of Advice
It is recommended to drink a sufficient amount of water or electrolyte to compensate for the water loss during diarrhoea or vomiting. It is recommended to take enough rest for a fast recovery. It is advised to avoid eating junk and oily foods which worsen the adverse effect of the drug. Your doctor will advise you to do a blood test and weight check during the medication. Applying a small amount of honey in the mouth ulcer, it will help you to relieve the pain caused by the ulcer.
FAQs
Q 1. When is the best time to take an Imatinate 100mg Capsule?
Take the capsule as prescribed by your doctor. Take an Imatinate 100mg Capsule at the same time every day. It is usually taken with a meal and a large glass of water to avoid stomach problems.
Q 2. Can I take an Imatinate 100mg Capsule if I have hepatitis B or a history of hepatitis B infection?
It is recommended to speak with your doctor if you have hepatitis B or a history of hepatitis B infection. This medicine can increase the risk of hepatitis B in individuals.
Q 3. Can I take an Imatinate 100mg Capsule if I am pregnant?
Imatinate 100mg Capsule is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Fact Box of Imatinate 100mg Capsule
Molecule name: Imatinib | Therapeutic class: Antineoplastics |
Pharmacological class: Tyrosine kinase inhibitor | Indications:
|
Dosage form: capsule | Habit form: No forming |
References
- Cipla (EU) Limited, Electronic Medicine Compendium (EMC), [Revised on Dec 2023], [Accessed on Mar 2024], https://www.medicines.org.uk/emc/files/pil.10133.pdf
- Novartis Pharmaceuticals Corporation, US Food and Drug Administration, [Revised on Sep 2016], [Accessed on Mar 2024], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021588s047lbl.pdf
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Disclaimer
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