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Irilieva 100mg Injection

Prescription Required
irinotecan

704

MRP: 1223.44

(You Save ₹519.44)

1 VIAL(s)

42% OFF
Irilieva 100mg Injection
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704

MRP: 1,223.44

Inclusive of all taxes

42% Off

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1 Vial(s)

1 Vial(s)

704.0/Unit
Prescription Required
Prescription Required

Salt Composition

IRINOTECAN

Marketer

Allieva Pharma Pvt. Ltd.

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Introduction to Irilieva 100mg Injection

Irilieva 100mg injection belongs to the group of medications called anti-cancer medicines or cytostatics. It consists of the active ingredient Irinotecan hydrochloride trihydrate. It is indicated for advanced colon cancer and rectal cancer in adults. It is prescribed alone or in combination with other chemotherapeutic agents. Cancer in the colon and rectum is prevalent in age groups above 50 and is further triggered by genetic and environmental factors. 


 

Myelosuppression (bone marrow suppression leading to low levels of RBC, WBC, and platelets in the blood) and diarrhea are this medication's most common adverse effects. Other common side effects of Irilieva 100mg injection are nausea, vomiting, abdominal pain, constipation, anemia, pain, fatigue, fever, infections including sepsis, abnormal bilirubin levels, hair loss, and weight loss. Inform your doctor if these side effects disturb or persist in you. Notify your doctor if you have chronic inflammatory bowel disease or bowel obstruction or if you took any live vaccines.


 

Inform your physician if you are allergic to Irinotecan and its ingredients. Before starting treatment, let your physician know if you have liver problems or jaundice, kidney and heart problems, asthma, high blood pressure or high cholesterol, or severe diarrhea. If you are smoking or have ever received radiation therapy, report to your healthcare provider. Consult your healthcare provider if you take other medicines, herbs, and supplements. Effective contraception (birth control) by males and females during treatment is important to avoid pregnancy. Your physician will perform blood tests during and before treatment to check for the effects of Irilieva 100mg Injection on blood counts or blood chemistry.

Uses of Irilieva 100mg Injection

  • Treatment of metastatic cancer of the colon and rectum (large intestine)

Therapeutic Effects of Irilieva 100mg Injection

Irilieva 100mg Injectionworks by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.

Interaction of Irilieva 100mg Injection with other drugs

Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications tend to interact with Irilieva 100mg Injectionand can cause potential side effects.

More Information about Irilieva 100mg Injection

  • Do not freeze.
  • Store protected from light at a temperature not exceeding 25°C.
  • Keep this medicine away from the sight and reach of children.
  • Always check the expiry date before consuming it.

How to consume Irilieva 100mg Injection

Take this medicine exactly as prescribed. Your healthcare professional administers it into your vein. Do not self-administer. Your physician will recommend a DNA test before taking this medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Safety Advice for Irilieva 100mg Injection

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

It is unsafe to use during breastfeeding as Irilieva 100mg Injectionand its metabolites are found in human milk. It must be discontinued for the duration of therapy. Consult your doctor for advice.  

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is not known whether it is safe to drink alcohol while taking Irilieva 100mg injection. Check with your doctor for advice.

Liver-Consult your doctor

Liver

Consult Your Doctor

Irilieva 100mg Injectionis used with caution in patients with liver impairment. Inform your physician before starting treatment if you have liver disease or jaundice. Your physician will monitor your liver functions and adjust the dose accordingly.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Irilieva 100mg Injectionis safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Driving-

Driving

After taking this medicine, you may feel dizzy or tired for the first 24 hours. Do not use any tools or drive during treatment with Irilieva 100mg injection. 

Pregnancy-unsafe

Pregnancy

Unsafe

Irilieva 100mg Injectionis unsafe during pregnancy as it may harm the developing baby. Women with potential childbearing use effective contraceptives during and after six months after treatment. 

Side Effects of Irilieva 100mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Early and late diarrhea
  • Allergic reactions
  • Kidney impairment
  • Lung problems
  • Low levels of RBC, WBC, and platelets in the blood

Common

  • Nausea, vomiting, abdominal pain
  • Constipation
  • Diarrhea
  • Anemia
  • Pain
  • Fatigue
  • Fever, infections including sepsis
  • Abnormal bilirubin levels
  • Hair loss
  • Weight loss

Word of Advice

This injection should be taken cautiously in patients with kidney disease or who have undergone dialysis. Diarrhea is the first sign of Campto 100mg injection. It may be serious if diarrhea starts more than 24 hours after administration of this medication. It should be treated immediately and kept under close supervision. If left untreated, it could lead to dehydration and serious chemical imbalances, which can be life-threatening. 

Try to avoid laxatives and stool softeners while taking Campto 100mg injection. Drink large amounts of water and rehydration fluids immediately. Take antidiarrheal treatment like loperamide. Notify your doctor if you experience any serious side effects. Contact your doctor for more information. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. 

FAQs about Irilieva 100mg Injection

Q1.

Do you lose your hair with Campto 100mg injection?

Hair loss can be a possible side effect of using Campto 100mg injection. It is recommended to discuss this potential side effect with your doctor for further information and guidance.

 

Q2.

Does Irilieva 100mg Injectioncause liver damage?

Irilieva 100mg Injectionmay cause liver impairment or damage. Inform your physician before starting treatment if you have liver disease or jaundice. Your doctor may adjust the dose based on your medical condition.

Q3.

What are the serious side effects of Campto 100mg injection? 

Some serious side effects of Irilieva 100mg Injection are early and late, diarrhea, allergic reactions, kidney impairment, lung problems, and low levels of RBC, WBC, and platelets in the blood.

Fact Box of Irilieva 100mg Injection

Molecule name: Irinotecan

Therapeutic class: Topoisomerase I inhibitors

Pharmacological class: Antineoplastics 

Indications: Colon and rectum cancer (large intestine cancer)

References

  1. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 1st June 2023], https://www.medicines.org.uk/emc/files/pil.7318.pdf
  2. Pharmacia & Upjohn Co, US Food & Drug Administration, [Revised on Dec 2014] [Accessed on 1st June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020571s048lbl.pdf
  3. I.D. Penman, C.W. Lees, Alimentary Tract and Pancreatic Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 837-920.
  4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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