Lox 2% Jelly uses as a Local anaesthesia

• Lox 2% Jelly for anal fissure helps relieve pain by numbing the affected area, making bowel movements less painful.

• Lox 2% Jelly for piles provides quick local anaesthetic relief from burning, itching, and discomfort in the anal region.

• Lignocaine 2 percent gel for urethritis pain helps numb the urethral lining and reduces pain or discomfort during urination or medical procedures.

Lox 2% Jelly works by blocking nerve signals in the body, temporarily numbing the area where it is applied or injected. It inhibits the conduction of pain signals to the brain, providing local pain relief or anesthesia.

1. Class III Antiarrhythmics (Moderate)
   Medicines like amiodarone may increase the cardiac effects of lignocaine. Use together only under medical supervision.

2. Other Local Anesthetics (Moderate)
   Using multiple anesthetic products can raise the risk of systemic toxicity. Avoid combining unless advised by your doctor.

3. Beta Blockers (Moderate)
   Beta blockers may slow lignocaine clearance, slightly increasing side effects. Use with caution if applied over large areas or frequently.

4. Cimetidine (Moderate)
   Cimetidine can reduce lignocaine metabolism, increasing the chance of adverse effects. Consult your doctor before using both together.

5. Drugs That Cause Methemoglobinemia (Severe)
   Medicines like nitrates, sulfonamides, dapsone, and benzocaine can raise the risk of methemoglobinemia when combined with lignocaine. Seek urgent care if you notice blue lips, dizziness, or breathing trouble.

• Do not store Lox 2 Jelly above 25 °C.

• Keep out of sight and reach of pets and children.

Lox 2% Jelly can be applied on various body areas, such as the neck, shoulders, knees, joints, and areas affected by postherpetic neuralgia, which is pain that persists after a shingles outbreak, depending on the site of pain or discomfort. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Lox 2% Jelly side effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Serious

• Severe allergic reactions

• Bluish discoloration of the skin

• Wheezing, itching, breathlessness, swelling of face, eyelids, mouth, etc.

• Changes in heart rate

• Low BP

Common

• Pain at the site of injection

• Temporary pain in the lower back, buttocks, and legs which resolves within a few days

• Numbness or tingling/paralysis of the legs

• Irregular bowel movements

• Tinnitus

• Loss of balance

• Dizziness

• Blurred vision

• Nausea

• Fear and anxiety

Use this Jelly strictly as directed and do not exceed the recommended dosage.
• Always check the product packaging for proper usage instructions.
• Consult your physician if you have any doubts or need clarification about the medicine.
• Keep Lox 2 percent Jelly away from excessive moisture and heat to prevent degradation.
• Store it in a cool and dry place for optimal effectiveness.

1. Mercury Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [ Revised on May 2021] [ Accessed on 31st May 2023], https://www.medicines.org.uk/emc/files/pil.4781.pdf/

2. Scilex Pharmaceuticals Inc, US Food and Drug Administration, [ Revised on Nov 2018] [Accessed on 31st May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207962s001lbl.pdf

3. Kenneth Drasner, Local Anesthetics, Lange's Basic and Clinical Pharmacology, 14th Edition, 2018, 459-473.

4. KD Tripathi, Local Anaesthetics, Essentials of Medical Pharmacology, 8th Edition, 2019, 386-398.