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Mapsplatin 50mg Injection
Last updated on 26 Sep 2026 | 08:41 AM (IST)
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Introduction
Mapsplatin 50mg Injection is a platinum-based anticancer medicine containing Oxaliplatin as its active ingredient. It belongs to the group of medicines known as platinum-based antineoplastic agents. This injection is mainly prescribed for stage III colon cancer after surgery (resection of the primary tumor) and for advanced or metastatic cancers of the colon and rectum. Doctors often use it in combination with other chemotherapy medicines to improve treatment results.
The main Mapsplatin 50mg uses in cancer include treating colorectal cancers that do not respond to cisplatin-based therapy. It works by damaging the DNA of cancer cells, stopping their growth and preventing the spread of tumors. This mechanism helps in controlling the progression of cancer and improving survival outcomes in many patients.
Your oncologist determines the Mapsplatin 50mg dosage for colon cancer based on your body surface area, overall health, and response to treatment. The medicine is given as an intravenous infusion in a hospital or cancer care setting under the supervision of a healthcare professional. It is usually administered every two or three weeks as part of a treatment cycle.
A unique feature of this drug is Mapsplatin 50mg cold sensitivity. Many patients experience tingling or numbness in the hands, feet, or throat when exposed to cold temperatures after treatment. Doctors usually advise avoiding cold drinks, ice, and low temperatures for a few days after each chemotherapy session to minimize discomfort.
Before starting therapy, patients or caregivers may check the Mapsplatin 50mg Injection price to plan their treatment budget. The price may vary depending on brand availability, manufacturer, hospital charges, and location. For convenience and accessibility, patients can buy Mapsplatin 50mg Injection online from authorized pharmacy websites that require a valid prescription. Online purchase ensures product authenticity and safe delivery through certified distributors.
In some cases, doctors might recommend a Mapsplatin 50mg substitute in India if the original brand is unavailable or if a cost-effective option is needed. Substitution should always be done under the guidance of an oncologist to ensure similar effectiveness and safety.
The Mapsplatin 50mg manufacturer follows stringent quality standards to ensure purity, potency, and safety for all batches produced. It is approved for medical use across India and trusted by oncology specialists for treating colorectal cancer and related malignancies.
Uses
mapsplatin 50mg uses include:
- Treatment of colon and rectal cancer.
How Mapsplatin 50mg Injection works
Mapsplatin 50mg Injectionworks by damaging the genetic material, such as DNA and RNA of the cancer cells, that interferes with the growth of cancer cells. It stops their growth and multiplication of cancer cells.
Interaction of Mapsplatin 50mg Injection with other drugs
Inform your doctor about any medications you are taking or have taken before the treatment with Mapsplatin 50mg Injection.
Storage conditions
- Store Mapsplatin 50mg Injection at a temperature below 30°C.
- Protect from light.
How to use Mapsplatin 50mg Injection
Mapsplatin 50mg Injection is given by slow injection into one of your veins (an intravenous infusion)
over 2 to 6 hours. Your physician will prescribe a dose according to your body surface area.
Safety Advice for Mapsplatin 50mg Injection
Breast Feeding
It is unsafe to breastfeed during treatment with Mapsplatin 50mg Injection. Your physician might suggest you stop breastfeeding for some time, depending on your condition.
Alcohol
It is unknown whether it is safe to consume alcohol with Mapsplatin 50mg Injection. Consult your doctor for any concerns regarding this.
Liver
Inform your physician before starting treatment with Mapsplatin 50mg Injection if you have liver disease or abnormal liver function. Your physician will prescribe the dose accordingly.
Lungs
Inform your physician before starting treatment with Mapsplatin 50mg Injection if you have lung disease or abnormal liver function. Your physician will prescribe the dose accordingly.
Driving
Avoid driving or using machinery if you experience side effects like dizziness, nausea, vomiting, vision problems, and other neurological symptoms.
Pregnancy
Mapsplatin 50mg Injection is unsafe to use during pregnancy; hence, it is not recommended. Women should use effective contraception during and after the 4 months of treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Mapsplatin 50mg side effects are
Serious side effects of Mapsplatin 50mg Injection are:
- Abnormal bleeding or bruising
- Severe allergic reactions
- Continuous diarrhea and vomiting
- Sore throat and fever
- Irregular heartbeat
- Muscle pain and weakness
- Mouth ulcers
- Extreme tiredness and breathlessness
- Headache
- Altered mental function
- Blurred vision
- Seizures
Common side effects of Mapsplatin 50mg Injection are:
- A reduced number of blood cells
- Unpleasant sensation in the throat
- Diarrhea
- Nausea, vomiting
- High risk of infections
- Indigestion and heartburn
- Blood in urine
- Blood clots
- High BP
- Depression and insomnia
- Low levels of calcium in the blood
Expert Tips
-
Women should use effective birth control for at least 4 weeks before starting and during treatment with Oxaliplatin.
-
Male patients are advised to use effective contraception during therapy and for 6 months after treatment to avoid fathering children.
-
Male patients should seek medical advice on sperm conservation before starting Mapsplatin 50mg Injection treatment.
-
Pregnant women must not use or handle this drug as it contains cytotoxic substances.
-
Mapsplatin 50mg Injection should only be handled by healthcare professionals using sterile single-use gloves, protective masks, hats, and goggles.
-
Vaccinations should be avoided during treatment with this drug, as they may cause serious side effects.
FAQs about Mapsplatin 50mg Injection
Q1.
What is Mapsplatin 50mg Injection used for?
Mapsplatin 50mg Injection is used to treat colon and rectal cancer. It belongs to the group of medications called Platinum-based antineoplastic agents.
Q2.
Is it safe to handle Mapsplatin 50mg Injection while pregnant?
No, Pregnant women should avoid handling Mapsplatin 50mg Injection as it contains cytotoxic agents.
Q3.
Can I take vaccinations while taking Mapsplatin 50mg Injection?
No, you should not get vaccinated with "live" or "attenuated" vaccinations, like the yellow fever vaccine, as it may weaken the immune system and cause severe adverse effects. Hence, without consulting your healthcare provider, this medication should not be taken with any vaccinations.
Q4.
Can I drive while taking Mapsplatin 50mg Injection?
Treatment with Mapsplatin 50mg Injection may raise the risk of dizziness, nausea, vomiting, vision problems, and other neurological symptoms that affect walking and balance. Therefore, when receiving Mapsplatin 50mg Injection treatment, avoid operating heavy machinery and driving.
Q5.
Is it safe to become a father while taking Mapsplatin 50mg Injection?
It is unsafe to become a father while on treatment and six months after treatment. Hence, effective contraceptives must be used during this time. Before receiving Mapsplatin 50mg Injection treatment, male patients should get advice on sperm conservation.
Q6.
Who is contraindicated to taking Mapsplatin 50mg Injection?
Patients with severe kidney problems, low blood cells, tingling, and numbness in the fingers and breastfeeding mothers should not use Oxaliplatin. It is also not recommended for patients who are allergic to Mapsplatin 50mg Injection and its ingredients.
Fact Box of Mapsplatin 50mg Injection
|
Molecule name |
Oxaliplatin |
|
Therapeutic class |
Platinum compounds |
|
Pharmacological class |
Antineoplastic or anti-cancer agent |
|
Indication |
Colorectal cancer |
References
- Hospira UK Limited, Electronic Medicines Compendium (EMC), [Revised on Dec 2020] [Accessed on 25th Jun 2021], https://www.medicines.org.uk/emc/files/pil.6286.pdf
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
- I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 837-920.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get accurate and trustworthy information that is reviewed by experts. The contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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