• Treatment of overactive bladder (OAB) symptoms

• Helps control urgency incontinence (inability to control bladder emptying)

• Reduces sudden, frequent urges to urinate

(Always use this medicine under medical supervision.)

The Megatas-S 50mg Tablet composition includes Mirabegron, which activates beta-3 adrenergic receptors in the bladder wall. This action helps relax the bladder muscles, increases bladder storage capacity, and reduces the frequent and sudden urges to urinate.

Before starting Megatas-S 50mg, inform your doctor about all the medicines you are taking, including:

• Antibiotics like clarithromycin

• Antifungal medicines like ketoconazole and itraconazole

• HIV medications

• Anticholinergic drugs for bladder or gut issues

Taking these with Megatas-S 50mg may increase the risk of side effects or affect how the medicine works.

• Storage: Store at a temperature below 30°C in a cool, dry place.
• Keep out of reach: Store safely out of the reach of children and pets.
• Packaging note: Keep the tablet in its original container until use.

• Take Megatas-S 50mg Tablet exactly as prescribed by your doctor.

• Swallow the tablet whole with water.

• Do not crush, chew, or split the tablet.

• Take the medicine at the same time each day for best results.

If you miss a dose, take it as soon as you remember. If it’s nearly time for your next dose, skip the missed one. Do not double the dose.

Like all medicines, Megatas-S 50mg Tablet may cause side effects. However, not everyone gets them.

Common side effects:

• Increased heart rate

• Nausea

• Constipation

• Dizziness

• Urinary tract infection

• Diarrhea

Serious side effects:

• Elevated blood pressure

• Irregular heartbeat

• Sudden severe headache

• Swelling of the face, mouth, or throat (angioedema)

Seek immediate medical attention if you experience serious side effects.

• Take the medicine at the same time each day.

• Do not stop the medication without your doctor’s advice.

• Inform your doctor about all other medicines you take.

• Stay hydrated and monitor your blood pressure regularly.

• If you miss a dose, skip it if it’s almost time for the next one.

• Ask your doctor if you need Megatas-S 50mg Tablet alternatives for better symptom management.

1. Astellas Pharma Ltd, Electronic Medicines Compendium (EMC), [Revised on December 2022] [Accessed on 6th June 2023], MIRABEGRON-TAB PL-Patient United Kingdom (Great Britain) en - TW366830 (medicines.org.uk)
2. Astellas Pharma US, Inc; [Revised on March 2021] [Accessed on 6th June 2023],label (fda.gov)
3. J. Goddard, A.N. Turner, Kidney and urinary tract disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 461-523.