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Melkeran 2 Tablet
Last updated on 31 Mar 2026 | 09:29 AM (IST)
₹958
MRP: ₹2395
(You Save ₹1437)
25 TABLET(s) IN A BOTTLE
Melkeran 2 Tablet
Salt Composition
MELPHALANMarketer
RMPL PHARMA LLP
Prepaid Only. Non-Returnable.
60% OFF
₹958
MRP: ₹2,395.00
Inclusive of all taxes
60% Off
Salt Composition
MELPHALANMarketer
RMPL PHARMA LLP
Prepaid Only. Non-Returnable.
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Introduction
Melkeran 2 Tablet contains the active constituent Melphalan. It is an anticancer agent that belongs to the class of medications called alkylating agents. Melkeran Tablet chemotherapy uses to treat multiple myeloma (a type of cancer of the bone marrow). It is also used to treat advanced breast and ovarian cancer. It is also indicated to treat polycythemia vera ( a disease that increases the number of red cells in your blood. This makes the blood thicken and causes blood clots). It works by reducing the number of abnormal cells your body makes.
Do not take Melkeran 2 Tablet if you are allergic to melphalan or any of the other ingredients. Inform your physician if you have had radiotherapy or cancer chemotherapy recently or have a kidney problem. Do not take this medicine if you are pregnant or planning for pregnancy. Inform your doctor if you have been vaccinated recently or planning to take any vaccination. Report to your physician immediately if you have a rash, lumps or hives on the skin, swollen face, eyelids, or lips, sudden wheeziness, and chest tightness after consuming the Melkeran Tablet cancer medicine. Melkeran price varies by the retailer.
Uses
Melkeran Tablet uses are:
Multiple myeloma
Advanced breast cancer
Advanced ovarian cancer
Polycythemia vera
How Melkeran 2 Tablet Works
Melkeran 2 Tablet is an alkylating agent. It exerts its cytotoxic action primarily due to the cross-linking of strands of DNA and RNA, as well as the inhibition of protein synthesis. It works by stopping or slowing the growth of cancer cells in your body.
Interaction of Melkeran 2 Tablet with other drugs
Live Vaccines (Life threatening)
Melphalan suppresses immune function, allowing live vaccines to cause serious infections. Live vaccines must be avoided during and after treatment.Other Bone Marrow Suppressing Medicines (Severe)
Combining melphalan with other chemotherapy drugs can greatly increase the risk of low blood counts, infections, and bleeding. Regular blood monitoring is required.Radiation Therapy (Severe)
Using radiation near the time of melphalan treatment can intensify bone marrow toxicity. Careful treatment planning is essential.Clozapine (Severe)
Both medicines can significantly lower white blood cell counts, increasing the risk of life threatening infections. This combination is usually avoided.Cyclosporine or Tacrolimus (Moderate)
These immunosuppressants may further weaken immune defenses when used with melphalan. Close monitoring for infections is advised.Warfarin and Other Anticoagulants (Moderate)
Reduced platelet counts may increase bleeding risk. INR and signs of bleeding should be monitored closely.Inactivated Vaccines (Mild)
Vaccine response may be reduced due to immune suppression. Vaccination timing may need adjustment.
Storage Conditions
Store in a refrigerator, 2° to 8°C
Protect the medicine from light and excessive moisture.
Keep the medicine out of reach of children and pets
If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Melkeran 2 Tablet
Your doctor will decide on the Melkeran 2 Tablet dosage and durationbased on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advices
Breast Feeding
Breastfeeding is not recommended in patients taking Melkeran 2 Tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is not known whether it is safe to consume alcohol with Melkeran 2 Tablet. Please consult your doctor.
Liver
There is limited information available on the use of Melkeran 2 Tablet in patients with liver disease. Please consult your doctor if you have any liver diseases.
Lungs
It is unknown whether Melkeran 2 Tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is not known whether Melkeran 2 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Pregnancy
Do not take Melkeran 2 Tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Side Effects
Melkeran side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
Decreased blood cell count
Nausea, vomiting, diarrhea
Mouth ulcers
Hair loss
Serious
Cardiac arrest
Liver inflammation
Hypersensitivity skin reactions
Acute renal failure
Lung inflammation
Expert tips
This medicine may affect your blood levels, so your doctor may recommend regular blood tests during treatment.
Do not take an extra dose to compensate for a missed dose.
This medicine may cause infertility, so discuss family planning with your doctor before starting treatment.
You may bleed, bruise, or get infections more easily while using this medicine.
Take proper precautions to reduce the risk of injury and infections during treatment.
FAQs
Q1.
Can a patient with kidney problems take Melkeran 2 Tablet?
Melkeran 2 Tablet should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.
Q2.
Does Melkeran 2 Tablet weaken the immune system?
The medicine can suppress your immune system and increase your chances of getting infections. Take precautions to prevent illness and injury.
Q3.
What if I overdose or take two doses of Melkeran 2 Tablet?
If you unknowingly overdosed or took two doses of Melkeran 2 Tablet, immediately inform your healthcare professional and seek medical advice.
Q4.
Should Melkeran 2 Tablet be taken with or without food?
Melkeran 2 Tablet comes as a tablet to take by mouth. It is usually taken on an empty stomach once a day. Your doctor will tell you how to take the medicine.
Q5.
Does Melkeran 2 Tablet cause hair loss?
Thinning or loss of your hair will usually start within two to four weeks of your first dose of Melkeran 2 Tablet. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.
Fact Box
Molecule name: | Melphalan |
Therapeutic class: | Antineoplastics |
Pharmacological class: | Alkylating agents |
Indications: |
|
References
Melphalan 2 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 7]. Available from: https://www.medicines.org.uk/emc/product/3806/smpc
ALKERAN ® 2 - melphalan [revised on 2021] [cited 2023 Apr 7]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/14691slr024_alkeran_lbl.pdf
KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
Disclaimer
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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