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Merofic Plus 1gm Injection
Last updated on 10 Jul 2026 | 12:04 PM (IST)
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Introduction to Merofic Plus 1gm Injection
Merofic Plus 1gm Injection is an antibiotic medication that contains two active ingredients called Meropenem and Sulbactam. It belongs to the medication class known as carbapenem antibiotics. It is used to treat various bacterial infections caused by susceptible organisms. Also, it is used to treat pneumonia, urinary tract infections, intra-abdominal infections, gynaecological infections, skin infections, meningitis, and sepsis. Harmful bacteria release toxins that harm tissues and cause illness. This medicine works by preventing bacteria from forming their protective cover, which is crucial for their survival. Sulbactam inhibits bacterial enzymes that can deactivate Meropenem. Meropenem may be used to manage neutropenic patients with fever suspected to be due to a bacterial infection.
Do not consume Merofic Plus 1gm Injection if you are allergic to Meropenem, Sulbactam, Penicillins, Cephalosporins, Carbapenems, or any of the ingredients in the medication. Before taking this injection, inform your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or are breastfeeding. Before starting the treatment, notify your doctor if you have liver or kidney problems or have experienced severe diarrhoea after taking other antibiotics.
The common side effects of Merofic Plus 1gm Injection are headache, stomach pain, being sick, increased numbers of platelets in the blood, and diarrhoea. Before starting the treatment, notify your doctor if you have any pre-existing medical conditions. Inform your doctor if you are on a salt-controlled diet. While you are on treatment, it is possible to have a positive Coombs test, indicating the presence of antibodies that may affect red blood cells; hence, your doctor may recommend blood tests to monitor your blood cell count and kidney function.
Uses of Merofic Plus 1gm Injection
Merofic Plus 1gm Injection is used to treat:
- Pneumonia (infection affecting the lungs)
- Lung and bronchial infections in patients with cystic fibrosis
- Bacterial septicemia
- Complicated urinary tract infections
- Complicated infections in the abdomen (stomach)
- Infections acquired during or after childbirth
- Complicated skin and soft tissue infections
- Acute bacterial infection of the brain (meningitis)
Therapeutic Effects of Merofic Plus 1gm Injection
Meropenem inhibits bacterial growth by disrupting cell walls, while Sulbactam prevents bacterial resistance by inhibiting beta-lactamase enzymes. Together, they enhance each other's effectiveness against a wider range of bacteria.
Interaction of Merofic Plus 1gm Injection with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications like valproic acid, probenecid, and oral anticoagulant agents may interact with Merofic Plus 1gm Injection and reduce effectiveness by causing undesirable side effects.
More Information about Merofic Plus 1gm Injection
- Do not store above 25°C
- Do not freeze.
How to consume Merofic Plus 1gm Injection
Merofic Plus 1gm Injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered as an injection or infusion in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Safety Advice for Merofic Plus 1gm Injection
Breast Feeding
Before starting the treatment, inform your doctor if you are breastfeeding. Due to the small amounts of Merofic Plus 1gm Injection that may pass into breast milk, your doctor must determine whether it is safe for you to use this medication while breastfeeding.
Alcohol
It is unknown whether consuming alcohol while taking Merofic Plus 1gm Injection is safe. Please speak with your physician.
Liver
Merofic Plus 1gm Injection should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions.
Lungs
It is unknown whether Merofic Plus 1gm Injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Merofic Plus 1gm Injection does not impair the ability to drive or operate machinery. However, if you experience any side effects, contact your doctor immediately.
Pregnancy
Limited information is available on the use of Merofic Plus 1gm Injection during pregnancy. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Your doctor will decide whether you should use this medicine.
Side Effects of Merofic Plus 1gm Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Rash, itching, or hives on the skin
- Swelling of the face, lips, tongue, or other parts
- Shortness of breath
- Troubling breathing
- Red or brown urine
Common
- Headache
- Stomach pain
- Being sick
- Increased numbers of platelets in the blood
- Diarrhea
Word of Advice
Inform your doctor if you're taking valproic acid along with Merofic Plus 1gm Injection. This combination might decrease valproic acid's effectiveness. Your healthcare provider may need to adjust your valproic acid dose or explore alternative treatments. In case you experience signs of severe skin reactions, promptly notify your doctor or nurse for appropriate treatment. Inform your doctor if you are on a sodium diet, as this medicine contains Sodium.
Before starting the treatment, inform your doctor about all the underlying medical conditions. Notify your doctor if you experience any serious side effects after taking Merofic Plus 1gm Injection. Contact your doctor for more information. It is highly advised not to skip the dose schedules as it may decrease the drug's effectiveness and increase the chance of bacteria developing resistance. It is generally suggested to complete the full treatment schedule as your doctor prescribes.
FAQs about Merofic Plus 1gm Injection
Q1.
How to manage the side effects of Merofic Plus 1gm Injection?
To manage the side effects of Merofic Plus 1gm Injection, follow the prescribed dosage and report side effects promptly. Stay hydrated and monitor the liver and kidney function. Maintain a healthy lifestyle by following a balanced diet and attending follow-up appointments.
Q2.
Can Merofic Plus 1gm Injection interact with other medications?
Yes, Merofic Plus 1gm Injection can interact with other medications and can cause undesirable side effects. Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment.
Q3.
What are the side effects of Merofic Plus 1gm Injection?
Common side effects of Merofic Plus 1gm Injection include headache, stomach pain, being sick, increased numbers of platelets in the blood, and diarrhea. It is crucial to consult your doctor for any concerns or persistent side effects.
Q4.
Can Merofic Plus 1gm Injection be taken during pregnancy or while breastfeeding?
Information regarding the usage of Merofic Plus 1gm Injection during pregnancy and breastfeeding is unknown. So, it is recommended to get healthcare professionals' advice before consuming the medicine. The potential benefits and risks of the medicine should be carefully assessed.
Fact Box of Merofic Plus 1gm Injection
Molecule name: Meropenem, Sulbactam
| Therapeutic class: Antibiotics |
Pharmacological class: Carbapenems | Indications: 1. Pneumonia (infection affecting the lungs) 2. Lung and bronchial infections in patients with cystic fibrosis 3. Bacterial septicemia 4. Complicated urinary tract infections 5. Complicated infections in the abdomen (stomach) 6. Infections acquired during or after childbirth 7. Complicated skin and soft tissue infections 8. Acute bacterial infection of the brain (meningitis) |
References
- Milpharm Limited, Electronic medicines compendium (EMC), [Revised on January 2023] [ Accessed on 14th August 2023], https://www.medicines.org.uk/emc/files/pil.5067.pdf
- AstraZeneca Pharmaceuticals LP, US FDA, [Revised on Dec 2016] [ Accessed on 14th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/050706s037lbl.pdf
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Penicillins, and other beta-lactam antibiotics, 12th edition, 2011, 1500.
- KD Tripathi, Essentials of Medical Pharmacology, Betalactam antibiotics, 7th edition, 2013, 731.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 10 Jul 2026 | 12:04 PM (IST)
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