Mounjaro 2.5 mg Injection is used for:

• Type 2 diabetes mellitus: To improve blood sugar control along with diet and exercise.

• Weight management: To support weight loss and weight maintenance in eligible adults with obesity or overweight and at least one weight-related health condition. Use it with a reduced-calorie diet and increased physical activity.

The approved uses may vary by product and regulatory approval.

Mounjaro 2.5 mg Injection contains Tirzepatide, which acts on two hormone receptors called GIP and GLP-1 receptors. These receptors are involved in blood sugar regulation and appetite.

Tirzepatide increases insulin release when blood sugar is high and reduces the release of glucagon, a hormone that raises blood sugar. It also slows stomach emptying and can reduce appetite and food intake. These actions help lower blood sugar and support weight management.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you take.

• Insulin and sulfonylureas: Using Mounjaro 2.5 mg Injection with these medicines can increase the risk of low blood sugar. Your doctor may adjust their dose.

• Medicines taken by mouth: Mounjaro 2.5 mg Injection slows stomach emptying and may affect the absorption of some medicines taken by mouth.

• Oral hormonal contraceptives: Tirzepatide can affect the absorption of oral hormonal contraceptives, particularly when treatment is started or the dose is increased. Discuss contraception with your doctor.

• Keep Mounjaro 2.5 mg Injection out of the sight and reach of children.

• Store Mounjaro 2.5 mg Injection according to the instructions provided with the product.

• Do not freeze Mounjaro 2.5 mg Injection.

• Protect Mounjaro 2.5 mg Injection from excessive heat and light where specified.

Use Mounjaro 2.5 mg Injection exactly as prescribed by your doctor. Treatment with Tirzepatide is usually started at a lower dose and increased gradually based on how you respond to treatment and tolerate the medicine.

Mounjaro 2.5 mg Injection is generally used once a week. The strength, dosage form and method of administration depend on the product. Follow the administration instructions provided with Mounjaro 2.5 mg Injection and those given by your doctor or pharmacist.

Do not change the dose or stop treatment without medical advice.

Common side effects:

• Nausea

• Diarrhoea

• Vomiting

• Constipation

• Abdominal pain

• Indigestion

• Decreased appetite

These effects are more common when the dose is increased and often become less noticeable with continued treatment.

Serious side effects:

• Severe allergic reactions

• Pancreatitis

• Severe gastrointestinal problems

• Gallbladder problems

• Low blood sugar, particularly when used with insulin or sulfonylureas

• Worsening diabetic eye disease in people with a history of diabetic retinopathy

Seek medical attention for severe or persistent abdominal pain, particularly if the pain spreads to the back.

• Use Mounjaro 2.5 mg Injection exactly as prescribed. Do not increase or reduce the dose on your own.

• Follow the diet and physical activity plan recommended by your doctor.

• Tell your doctor if you use insulin or a sulfonylurea because Mounjaro 2.5 mg Injection can increase the risk of low blood sugar when used with these medicines.

• Seek medical advice if you develop severe or persistent abdominal pain.

• Tell your doctor about any changes in vision, especially if you have diabetic retinopathy.

• If you use oral hormonal contraceptives, discuss contraception with your doctor when starting Mounjaro 2.5 mg Injection and after dose increases.

1. https://www.cdscoonline.gov.in/CDSCO/cdscoDrugs

2. https://www.ema.europa.eu/en/medicines/human/EPAR/mounjaro

3. https://www.ema.europa.eu/en/documents/product-information/mounjaro-epar-product-information_en.pdf

4. https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadCommitteeFiles/Recommendations%20Endocrinology%20Metabolism%2013.01.2026.pdf