Quick Summary
Mutrans NRX 5mcg Patch
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹491
MRP: ₹613.13
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2 PATCHE(s) IN A BOX
Mutrans NRX 5mcg Patch
Salt Composition
BUPRENORPHINE TRANSDERMAL PATCHMarketer
6IPAIN HEALTHCARE PRIVATE LTD
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₹491
MRP: ₹613.13
Inclusive of all taxes
20% Off
Salt Composition
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Introduction to Mutrans NRX 5mcg Patch
Mutrans NRX 5mcg patch contains an active component as Buprenorphine transdermal patch. It is a medication used to manage moderate to severe chronic pain as part of opioid dependence treatment. It provides continuous delivery of buprenorphine, a partial opioid agonist, through the skin into the bloodstream over a period of time. The patch helps maintain a steady blood level of medication, reducing the risk of misuse or diversion. The transdermal delivery system bypasses the gastrointestinal tract, reducing the likelihood of common opioid-related side effects such as nausea and vomiting. Additionally, the controlled release of buprenorphine may result in a reduced incidence of certain side effects. The simplicity of using a patch can enhance treatment adherence, as it eliminates the need for frequent dosing and reduces the chances of missing a dose. This can be especially advantageous for individuals with complex medication regimens or those who have difficulty swallowing pills.
If you have a known hypersensitivity or allergy to this medication or any of the components of the patch, its use is contraindicated. It should be used cautiously in individuals with respiratory conditions, such as chronic obstructive pulmonary disease (COPD), as it can affect respiratory function. This medication can potentially cause or worsen paralytic ileus, a condition characterized by impaired bowel motility. It should be used with caution in individuals at risk for bowel obstruction. Compared to immediate-release oral opioids, the patch may have a slower onset of action, meaning it may take some time to achieve pain relief. Similarly, the effects may persist even after the patch is removed, which can be a disadvantage in case of adverse reactions.
Uses of Mutrans NRX 5mcg Patch
- Chronic Pain
Therapeutic Effects of Mutrans NRX 5mcg Patch
The Mutrans NRX 5mcg patch provides a therapeutic effect by delivering a continuous and controlled release of buprenorphine into the bloodstream. As a partial opioid agonist, this medication binds to opioid receptors in the brain, producing analgesic (pain-relieving) effects for individuals with chronic pain and reducing withdrawal symptoms and cravings in those undergoing opioid dependence treatment.
Interaction of Mutrans NRX 5mcg Patch with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Mutrans NRX 5mcg patch, reducing effectiveness by causing undesirable side effects.
More Information about Mutrans NRX 5mcg Patch
- Stored in the temperature between 20°C to 25°C (68°F to 77°F).
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Mutrans NRX 5mcg Patch
To use the Mutrans NRX 5mcg patch, clean and dry the desired application site on the upper arm, chest, back, or side. Avoid areas with broken or irritated skin. Open the patch package and remove the protective liner, being careful not to touch the adhesive. Apply the patch firmly to the skin, ensuring good contact. Press down on the patch for about 30 seconds to secure it in place. Change the patch as directed by your healthcare provider, typically every 7 days.
Safety Advice for Mutrans NRX 5mcg Patch
Breast Feeding
When it comes to the safety of using the Mutrans NRX 5mcg patch while breastfeeding, it is important to consult with a healthcare professional.
Alcohol
Both buprenorphine and alcohol can cause central nervous system depression, leading to sedation, impaired cognitive function, and respiratory depression. When used together, the effects can be additive, potentially increasing the risk of severe respiratory depression and other adverse effects
Liver
Buprenorphine is primarily metabolized in the liver, and liver impairment can affect the metabolism and clearance of medications. In individuals with liver conditions, such as cirrhosis or hepatitis, the levels of buprenorphine in the body may be altered.
Lungs
Buprenorphine, like other opioids, can cause respiratory depression and a decrease in breathing rate and depth. In individuals with pre-existing lung conditions, such as chronic obstructive pulmonary disease (COPD) or asthma, the risk of respiratory depression may be heightened.
Driving
The use of the Mutrans NRX 5mcg patch can affect driving and operating machinery due to its potential to cause sedation and impair cognitive and motor function.
Pregnancy
If you are pregnant or planning to become pregnant, it is crucial to inform your healthcare provider. They can evaluate your circumstances, weigh the potential risks and benefits, and provide guidance specific to your situation.
Side Effects of Mutrans NRX 5mcg Patch
Mutrans NRX 5mcg patch causes some side effects like all medications, although not everyone will experience them.
Serious:
- Difficulty breathing or shortness of breath
- Severe drowsiness or sedation
- Slowed or irregular heartbeat
- Allergic reactions, such as rash, hives, or swelling of the face, lips, or throat
- Mental or mood changes
- Signs of liver problems (yellow skin or eyes, dark urine, or persistent abdominal pain)
Common:
- Nausea and vomiting
- Constipation
- Drowsiness or sedation
- Headache
- Sweating
- Skin reactions at the patch application site, such as itching, redness, or irritation
Word of Advice
Before using the Mutrans NRX 5mcg patch, several precautions should be considered. Inform your healthcare provider about any allergies, medical conditions, or medications you are taking, as they may interact with buprenorphine. Caution is advised in individuals with respiratory disorders, liver or kidney problems, or a history of substance abuse. The patch should be applied to intact skin only and avoided on areas with rashes, burns, or wounds. Pregnant and breastfeeding women should consult a doctor before using it. Regular monitoring of vital signs, respiratory function, and liver function is recommended during treatment. It is important to avoid abrupt discontinuation of the patch without medical guidance, as it may result in withdrawal symptoms. The patch should be used cautiously in the elderly, as they may be more susceptible to the medication's effects. Additionally, special attention should be given to individuals with a history of mental health disorders or seizures.
FAQs about Mutrans NRX 5mcg Patch
Q1.
Can I swim or take a bath while wearing the Mutrans NRX 5mcg patch?
It is generally recommended to avoid exposing the patch to excessive water, such as swimming or bathing, as it may affect the patch's adherence and effectiveness. However, specific instructions may vary, so it's best to consult your healthcare provider or read the product labeling for guidance.
Q2.
Can I cut or trim the Mutrans NRX 5mcg patch to adjust the dosage?
No, this patch should not be cut or trimmed. Altering the patch can lead to inconsistent dosage delivery, resulting in inadequate pain control or an increased risk of side effects. Follow your healthcare provider's instructions on properly using the patch and consult them if you need a dosage adjustment.
Q3.
Can I apply heat or use heating pads over the Mutrans NRX 5mcg patch to relieve pain?
It is not recommended to apply heat sources or use heating pads over the buprenorphine patch. Heat can increase the absorption of buprenorphine and may lead to higher blood levels and potentially dangerous side effects. Follow your healthcare provider's advice on alternative pain relief methods that are safe to use with the patch.
Q4.
Can I use the Mutrans NRX 5mcg patch if I have a skin condition or irritation?
The Mutrans NRX 5mcg patch should not be applied to areas of the skin with rashes, burns, or wounds. It is important to have intact skin for proper absorption of the medication. If you have a skin condition or irritation, discuss it with your healthcare provider to determine the most appropriate course of treatment.
Q5.
Can I apply any lotions, creams, or oils on the skin where the Mutrans NRX 5mcg patch is placed?
It is generally recommended to avoid applying lotions, creams, or oils to the area where the patch is applied. These substances may interfere with the adhesion of the patch and affect its effectiveness. If you have any concerns or specific skin care needs, consult your healthcare provider for guidance.
Q6.
Can I exercise or engage physically while wearing the Mutrans NRX 5mcg patch?
Physical activities or exercise should not interfere with this patch. However, excessive sweating or prolonged exposure to heat generated during intense exercise may affect the patch's adherence. Discussing your exercise routine with your healthcare provider to ensure proper patch placement and effectiveness is best.
Q7.
What are the common side effects of the Mutrans NRX 5mcg patch?
The Mutrans NRX 5mcg patch may cause common side effects, including constipation, nausea, vomiting, headache, dizziness, drowsiness, dry mouth, and sweating. These side effects are usually mild to moderate and tend to improve with continued use. However, if any side effects persist or worsen, it is important to consult your healthcare provider for further guidance. It's worth noting that this is not an exhaustive list of potential side effects, and individual experiences may vary.
Fact Box of Mutrans NRX 5mcg Patch
Molecule name: Buprenorphine Transdermal Patch | Therapeutic class: Analgesics |
Pharmacological class: Partial mu-opioid receptor agonists | Indications: Pain management |
References
- Lonza Biologics Tuas Pte Ltd, European Medicines Agency, [Revised on: 4/14/2020] [Accessed on 19th June 2023], https://www.ema.europa.eu/en/documents/product-information/reblozyl-epar-product-information_en.pdf
- Amneal Pharmaceuticals, LLC, US Food and Drug Administration, [Revised on 2017] [Accessed on 19th June 2023],https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2020/211586Orig1s000ltr.pdf
Disclaimer
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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