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Nitisone 2 Capsule
Last updated on 19 Aug 2026 | 06:50 AM (IST)
₹10148
MRP: ₹12375
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60 CAPSULE(s) IN A BOTTLE
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₹10148
MRP: ₹12,375.00
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Lasinone 2mg Capsule
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₹ 273.45/capsule
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Introduction
Nitisone 2 Capsule is a metabolic disorders drug with an active ingredient called Nitisinone. It belongs to the family class known as enzyme inhibitors. This medicine is used to treat a rare disease called hereditary tyrosinemia type 1 (adults, adolescents, and children of all ages) and alkaptonuria (adults). It works by blocking the breakdown of the amino acid tyrosine and preventing the accumulation of harmful substances. Your physician may ask you to follow a specialized diet while taking Nitisinone for hereditary tyrosinemia type 1 (HT-1) or alkaptonuria (AKU) to manage the conditions effectively.
Nitisone 2 Capsule should not be consumed if you are allergic to Nitisinone or any of its ingredients in the medication. Before taking this medicine, it is important to consult with your doctor. Inform your doctor if you have or have a history of any liver or kidney conditions. Notify your doctor if you have leukopenia (reduced WBC in the blood) or thrombocytopenia (reduced plated count in the blood). Your doctor will monitor platelet and white blood cell counts before initiating the treatment.
Nitisone 2 Capsule Price may vary depending on your location and pharmacy. It's best to check with local pharmacies for the most accurate pricing.
Uses
Nitisone 2 capsule uses are
Hereditary tyrosinemia type 1 (adults, adolescents, and children)
Alkaptonuria (adults)
How Nitisone 2 Capsule works
Nitisone 2 Capsule works by blocking the breakdown of the amino acid tyrosine, preventing its buildup in the body. This mechanism helps in the treatment of conditions such as hereditary tyrosinemia type 1 (HT-1) and alkaptonuria (AKU).
Interaction of Nitisone 2 Capsule with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Nitisone 2 Capsule and can cause undesirable side effects.
Storage
Keep out of sight and reach of pets and children.
Do not freeze the medicine.
Do not store above 30°C.
Always check the expiry date before consuming it.
How to take Nitisone 2 Capsule
Take the Nitisone 2 Capsule as your physician advises. Usually, this capsule will be taken once a day. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.
Safety Advice
Pregnancy
Taking Nitisone 2 Capsule while pregnant may be unsafe because it may affect the unborn child. Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant.
Breast Feeding
It is unsafe to breastfeed while taking Nitisone 2 Capsule. Before starting the treatment, inform your doctor if you are breastfeeding.
Lungs
It is unknown whether Nitisone 2 Capsule is safe for patients with lung problems. Notify your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Liver
Nitisone 2 Capsule should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions.
Alcohol
It is unknown whether it is safe to consume alcohol while taking Nitisone 2 Capsule. Please consult your doctor for more information.
Driving
Nitisone 2 Capsule could alter the driving ability or operating machinery capacity by causing dizziness, headaches, nausea, and tiredness.
Side effects
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Nitisone 2 Capsule side effects include
Common
Elevated levels of tyrosine
Reduced platelet count
Decreased lymphocyte count
Conjunctivitis (eye inflammation)
Corneal opacity (clouding of the cornea)
Photophobia (sensitivity to light)
Eye irritation (keratopathy)
Eyelid inflammation
Cataract (clouding of the eye's lens)
Reduced granulocyte count
Itching
Expert Tips
Do not stop taking the medicine unless advised by your doctor.
Do not double-dose to make up for a missed dose.
Liver and kidney patients should use Nitisone 2 Capsule cautiously and inform their doctor about any underlying conditions.
Dose adjustments may be required based on age, weight, and medical history.
Do not breastfeed while taking Nitisone 2 Capsule.
Notify your doctor if you experience any serious side effects.
Contact your doctor for more information.
FAQs
Q1.
What steps can be taken to minimize side effects while using Nitisone 2 Capsule?
To manage the side effects of Nitisone 2 Capsule, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor blood pressure regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Q2.
Can Nitisone 2 Capsule cause vision problems?
Nitisone 2 Capsule may cause vision problems as a side effect, including other visual disturbances, pain, irritation, and inflammation. If you experience any changes in your eye while taking Nitisone 2 Capsule, notify your doctor immediately.
Q3.
Can you take Nitisone 2 Capsule when pregnant?
Consult your medical professional regarding the use of Nitisone 2 Capsule during pregnancy. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
Q4.
What are the side effects of Nitisone 2 Capsule?
Common side effects of Nitisone 2 Capsule include elevated levels of tyrosine, reduced platelet count, decreased lymphocyte count, conjunctivitis (eye inflammation), corneal opacity (clouding of the cornea), and other visual problems. It is mandatory to consult your doctor for any concerns or persistent side effects.
Q5.
What should I do if I miss a dose of Nitisone 2 Capsule?
If you miss a capsule dose, take it as soon as possible. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose the Nitisone 2 Capsule.
Fact box
Molecule Name | Nitisinone |
Therapeutic class | Metabolic disorders |
Pharmacological class | Enzyme inhibitors |
Indications | 1. Hereditary tyrosinemia type 1 (adults, adolescents, and children) 2. Alkaptonuria (adults) |
References
LogixX Pharma Ltd, Electronic Medicines Compendium (EMC), [Revised on December 2022] [Accessed on 1st June 2023], pil.14734.pdf (medicines.org.uk)
Apotek Produktion & Laboratorier, US Food and Drug Administration, [ Revised on November 2021] [ Accessed on 1st June 2023], https://www.orfadin.com/pdf/full-prescribing-information.pdf
European medicines agency, [ Accessed on 1st June 2023], Orfadin | European Medicines Agency (europa.eu)
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr Arathy J S
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 19 Aug 2026 | 06:50 AM (IST)
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