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NITSUM 100MG INJECTION
Salt Composition : Carmustine
Manufacturer : CELON LABORATORIES LTD
Origin of Medicine : India
Introduction to Nitsum 100mg Injection
Nitsum 100mg Injection belongs to the group of medications known as Antineoplastic. It contains active constituent carmustine. It is used as palliative therapy (preventing and relieving the suffering of patients) in certain types of cancers, like multiple myeloma, Hodgkin’s disease, non-Hodgkin’s lymphomas, and brain tumors (glioblastoma, medulloblastoma, astrocytoma, and metastatic brain tumors). Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner. This medicine is given alone or in combination with other medicines for cancer treatment.
Headache, dizziness, blurred vision, redness in the eye, nausea, vomiting, darkening of an area of nails or skin, fall in blood pressure, inflammation of veins, constipation, diarrhea, hair loss, anemia, flushing of the skin and lack of voluntary coordination of muscle movements are the common side effects of Nitsum 100mg Injection. Inform your doctor if these side effects disturb or persist in you.
Report to your doctor if you are allergic to Nitsum 100mg injection and its ingredients. It is contraindicated in patients with low blood platelets, white blood cells, red blood cells, and kidney dysfunction. Administration of this medicine can cause delayed bone marrow (a spongy substance inside the bone that produces blood cells) suppression and lung damage. Your physician will monitor your blood counts and liver and kidney function regularly. Tell your doctor if you have epilepsy, liver disorders, or alcohol addiction, as this medicine contains alcohol. Nitsum 100mg Injection should not be used during pregnancy and breastfeeding.
Uses of Nitsum 100mg Injection
- Multiple myeloma (cancer of a kind of white blood cell called plasma cell)
- Hodgkin’s disease (lymphoid tumor)
- Non-Hodgkin’s lymphomas (lymphoid tumors)
- Brain tumors (medulloblastoma, glioblastoma, astrocytoma, and metastatic brain tumors)
Therapeutic Effects of Nitsum 100mg Injection
Nitsum 100mg Injection works by slowing the growth of cancer cells by damaging both DNA and RNA. It prevents the cancer cells from growing and kills them.
Interaction of Nitsum 100mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Nitsum 100mg Injection and cause undesirable side effects.
More Information about Nitsum 100mg Injection
- Keep Nitsum 100mg Injection out of sight and reach of children.
- Store in the refrigerator at 2°C - 8°C.
- Protect from light.
How to consume Nitsum 100mg Injection
Nitsum 100mg Injection will be given to you by a doctor or nurse. It is administered into a vein by a drip over one to two hours.
Safety Advices for Nitsum 100mg Injection
Nitsum 100mg Injection is unsafe to use during pregnancy as it may harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking Nitsum 100mg Injection. It will be given to you if clearly needed
You should not breastfeed while taking Nitsum 100mg Injection. Inform your doctor if you are breastfeeding before taking this medicine.
Inform your doctor if you have any lung damage or condition before starting treatment with Nitsum 100mg Injection.
Nitsum 100mg Injection is probably unsafe to use if you have any liver disorders. Because it might cause reversible liver toxicity in high-dose therapy.
Avoid consuming alcohol with this medication as it may cause unpleasant side effects.
Nitsum 100mg Injection could affect your ability to drive, as it contains alcohol. Hence, avoid driving if you are unwell.
Side Effects of Nitsum 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
- Severe allergic reactions (swelling of eyelids, face, lips, itching, rash, difficulty in breathing, feeling faint)
- Delayed myelosuppression (decrease in blood cells in bone marrow)
- Lung damage
- Headache, dizziness
- Blurred vision, redness in the eye
- Nausea, vomiting
- Darkening of an area of nails or skin
- Fall in blood pressure
- Inflammation of veins
- Constipation, diarrhea
- Hair loss
- Reactions at the injection site, flushing of the skin
- Lack of voluntary coordination of muscle movements
Word of Advice
Women of childbearing potential are advised to use effective contraceptives while taking Nitsum 100mg Injection. Male patients must use birth control during treatment with this medication and for 6 months to prevent their partners from becoming pregnant. Your doctor will monitor your blood count to avoid toxicity in the bone marrow, and the dose will be adjusted if necessary.
Q 1. 1. Is Nitsum 100mg Injection a chemotherapy medication?
Yes, Nitsum 100mg Injection is a chemotherapy medication that is indicated to treat brain tumors, multiple myeloma, Hodgkins, and non-Hodgkin lymphoma.
Q 2. 2. Can I take Nitsum 100mg Injection during my pregnancy?
No, It is unsafe to take Nitsum 100mg Injection during pregnancy as it may harm the baby. Consult your doctor before taking this medication.
Q 3. 3. Can Nitsum 100mg Injection be self-administered?
No, Nitsum 100mg Injection should not be taken on its own. It is administered by your healthcare provider on your vein.
Q 4. 4. In which conditions should I avoid taking Nitsum 100mg Injection?
Nitsum 100mg Injection should not be used in patients with low blood count, kidney dysfunction, bone marrow suppression, and lung damage.
Q 5. 5. Are there any potential or possible side effects of Nitsum 100mg Injection?
Nitsum 100mg Injection may cause side effects such as headache, dizziness, nausea, vomiting, fall in blood pressure, constipation, diarrhea, hair loss, and anemia. However, if these side effects worsen or persist, contact your physician immediately.
Q 6. 6. I am suffering from epilepsy. Can I take Nitsum 100mg Injection?
Nitsum 100mg Injection is not recommended for epilepsy, as this medicine contains alcohol. If you have any concerns regarding this, discuss them with your doctor.
Fact Box of Nitsum 100mg Injection
Molecule name: Carmustine
|Therapeutic class: Alkylating agents|
Pharmacological class: Antineoplastics
1. Multiple myeloma (cancer of a kind of white blood cell called plasma cell)
2. Hodgkin’s disease (lymphoid tumor)
3. Non-Hodgkin’s lymphomas (lymphoid tumors)
4. Brain tumors (medulloblastoma, glioblastoma, astrocytoma, and metastatic brain tumors)
1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1686.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 876.
3. Tillomed Laboratories Ltd, Electronic medicines compendium (emc), [ Revised on Nov 2021] [ Accessed on 22 Nov 2022], https://www.medicines.org.uk/emc/files/pil.11176.pdf
4. Heritage Pharmaceuticals Inc, US Food and Drug Administration, [ Revised on March 2017] [ Accessed on 22 Nov 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/017422s055lbl.pdf
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