• Chemotherapy-induced neutropenia
• Chemotherapy-induced fever
• Chemotherapy-induced infections

Nufil SF 300mcg Injection works by stimulating the bone marrow to produce and release white blood cells, specifically granulocytes, into the bloodstream. This increase in white blood cell production helps strengthen the body's immune response, making it particularly valuable in treating conditions where a higher white blood cell count is needed, such as during chemotherapy or in cases of neutropenia (low white blood cell count).

Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Nufil SF 300mcg Injection and reduce effectiveness by causing undesirable side effects.

• Store Nufil SF 300mcg Injection in refrigerator at (2°C to 8°C).
• Do not freeze.
• Protect from light and moisture.

Nufil SF 300mcg Injection can be administered subcutaneously (under the skin) or intravenously (into a vein). The choice of administration method depends on the specific medical condition and treatment plan.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

• Sudden signs of allergy (rash, itching, swelling of lips, tongue, wheezing)
• Acute respiratory syndrome (cough, fever together with troubled breathing)
• Enlargement of the spleen (pain in the upper left belly, pain below the left rib cage, pain at the tip of the shoulder)
• Blood poisoning (combination of very cold, high heart rate, confusion, shortness of breath, sweaty skin, and extreme pain)
• Capillary leak syndrome (puffiness, abdominal swelling, and feeling of fullness, difficulty breathing, and tiredness)
• Kidney injury (Puffiness in face or ankles, blood in urine or brown-colored urine)

Common

• Nausea, vomiting
• Headache, dizziness
• Decreased platelet, red blood cell count
• Diarrhea
• Unusual hair loss
• Troubled sleeping
• Inflammation of lung
• Loss of appetite
• Constipation
• Pain when passing urine
• Muscle spasm
• Nosebleeds

Individuals should monitor their temperature regularly, as Nufil SF 300mcg Injection can increase the risk of fever and infection. Notify your physician if a fever develops. Include a balanced diet rich in nutrients to support the immune system. If appetite is affected, consider consulting a nutritionist for dietary recommendations.

1. Amgen Europe BV, Electronic medicines compendium (EMC), [ Revised on July 2022] [ Accessed on 2 Sep 2023], https://www.medicines.org.uk/emc/files/pil.3000.pdf
2. Amgen, US Food and Drug Administration, [ Revised on March 2015] [Accessed on 2 Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/103353s5183lbl.pdf
3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 876.