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OCANAT 10MG TABLET_1
OCANAT 10MG TABLET_2
OCANAT 10MG TABLET_1
15% Off

Ocanat 10mg Tablet

Prescription Required

Salt Composition : Obeticholic Acid

Manufacturer : NATCO PHARMA LTD

Origin of Medicine : India

MRP: 500
Price :425
You Save :75 (15%)

10 Tablet(s) In A Strip


Introduction to Ocanat 10mg Tablet

Ocanat 10mg Tablet is a gastrointestinal agent belonging to the farnesoid X-receptor agonist category containing the active ingredient Obeticholic acid. It is mainly used to treat primary biliary cholangitis (PBC). This chronic liver disease can be caused by inflammation and damage to the small bile ducts in the liver, which leads to reduced bile flow, liver damage, and potential scarring (fibrosis).

This drug is contraindicated in individuals with known hypersensitivity or allergy to any other ingredients in the medicine. The levels of certain medications, such as theophylline (used to aid breathing) and tizanidine (used to relieve muscle stiffness and restriction), may increase when taken with Ocanat 10mg Tablet. Your doctor may need to monitor the levels of these medications in your blood and adjust their dosages if necessary. Medications like cholestyramine, colestipol, and colesevelam, which are used to lower blood cholesterol levels, may reduce the effectiveness of this drug. If you are taking these medicines, your doctor will advise you to take this medication at least 4 to 6 hours before or after taking the bile acid-binding resin to allow sufficient time for their separate absorption. The use of this drug is not recommended in children or adults.

Before taking Ocanat 10mg Tablet, it is necessary to consult with your physician if you have any concerns about complete blockage of bile ducts in your gallbladder or worsening liver health. Your physician will conduct regular blood tests to monitor your liver function. Itching may occur as a side effect of this drug, and in some cases, it may become severe (intense itching over much of the body). If you experience difficult-to-tolerate itching, your doctor may prescribe additional medications to manage it or adjust your dosage. This drug is not recommended for use during pregnancy due to the lack of sufficient data and experience with its use in pregnant women. As a precautionary measure, pregnant individuals should avoid taking this drug.


Uses of Ocanat 10mg Tablet

  • Treatment of primary biliary cholangitis (PBC)

Therapeutic Effects of Ocanat 10mg Tablet

Ocanat 10mg Tablet activates the farnesoid X receptor (FXR) in the liver. This activation has various beneficial effects, including reducing liver inflammation, promoting bile flow, and slowing down or reversing liver fibrosis. These actions help to manage the symptoms and progression of PBC.


Interaction of Ocanat 10mg Tablet with other drugs

Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Ocanat 10mg Tablet and reduce effectiveness by causing undesirable side effects.


More Information about Ocanat 10mg Tablet

  • Store Ocanat 10mg Tablet below (25°C).
  • Protect from light and moisture.

How to consume Ocanat 10mg Tablet

Take the Ocanat 10mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.


Safety Advices for Ocanat 10mg Tablet

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Pregnancy

  

Ocanat 10mg Tablet is not recommended for use during pregnancy due to the lack of sufficient data and experience with its use in pregnant women. As a precautionary measure, pregnant individuals should avoid taking this drug.

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Breast Feeding

  

It is unknown if Ocanat 10mg Tablet passes into the breast milk or if it will harm your baby. Please consult your doctor before breastfeeding. 

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Lungs

  

It is unknown whether Ocanat 10mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment. 

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Liver

  

Ocanat 10mg Tablet is safe to use in patients with liver problems. Inform your physician if you have liver diseases before initiating the treatment. 

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Alcohol

  

It is unknown whether consuming alcohol interacts with the Ocanat 10mg Tablet. Please consult your doctor for more advice.

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Driving

  

Ocanat 10mg Tablet has negligible influence on the ability to drive or use machines. Consult your doctor for more information. 


Side Effects of Ocanat 10mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Worsening of liver problems ( white of the eyes or yellowing of skin, black, tarry or bloody stools, coughing up or vomiting blood, confusion, slurred speech, mood swings)
  • Severe itching
  • Lower HDL-C (good cholesterol)

Common

  • Tiredness
  • Stomach pain, discomfort, constipation
  • Joint pain, mouth, and throat pain
  • Dizziness
  • Fast or irregular heartbeat
  • Fever
  • Dryness, irritation, or redness of the skin
  • Rash
  • Swelling of ankles, hands, or feet
  • Thyroid hormone irregularity

Word of Advice

Inform your physician if you are taking any medicines to lower blood cholesterol levels. Certain cholesterol-lowering medications can interact with Ocanat 10mg Tablet and may affect their effectiveness or increase the risk of side effects. Your physician must be aware of all the medications you are taking to make appropriate adjustments to your treatment plan if necessary.


FAQs

Q 1. Can Ocanat 10mg Tablet be used in combination with other medications for PBC?

Ocanat 10mg Tablet may be used as a monotherapy or in combination with other medications, depending on the patient's specific condition. It is necessary to inform the doctor about all medications, supplements, and herbal products being taken to avoid serious drug interactions.

Q 2. Are there any specific contraindications or precautions with Ocanat 10mg Tablet?

Individuals with certain medical conditions or a history of certain liver diseases may need special consideration before starting Ocanat 10mg Tablet. Pregnant and breastfeeding individuals should consult their healthcare provider before using this medication.

Q 3. Can anyone take Ocanat 10mg Tablet for PBC?

Ocanat 10mg Tablet may not be suitable for everyone, and its use should be determined by a physician. It is generally prescribed for patients with primary biliary cholangitis who cannot tolerate other therapies.

Q 4. What are the common side effects of Ocanat 10mg Tablet?

Common side effects of Ocanat 10mg Tablet may include itching, fatigue, abdominal pain, nausea, joint pain, and constipation. Patients may experience different side effects, and it is essential to report any unusual or severe symptoms to the doctor immediately.

Q 5. How is Ocanat 10mg Tablet administered?

Ocanat 10mg Tablet is available in the form of tablets for oral administration. It can be taken once daily, with or without food, as directed by the physician.


Fact Box of Ocanat 10mg Tablet

Molecule name: Obeticholic acid

Therapeutic class: Gastrointestinal agents

Pharmacological class:  Farnesoid X-receptor agonist

Indications: Treatment of primary biliary cholangitis (PBC)


References

  1. Almac Pharma Services (Ireland) Limited, Electronic medicines compendium (EMC), [Revised on Aug 2022] [ Accessed on 24th August 2023], https://www.medicines.org.uk/emc/files/pil.2561.pdf
  2. Intercept Pharmaceutical Inc, US Food and Drug Administration, [ Revised on Jan 2018] [Accessed on 24th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/207999s003lbl.pdf
  3. Bertram G. Katzung, Lange's Basic and Clinical Pharmacology, Drugs Used in treating Gastrointestinal Diseases, 14th Edition, 2018, 1112.

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