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Oriadali 40mg Injection

Prescription Required
Cold Chain Required
adalimumab

₹5555

MRP: ₹26249

(You Save ₹20694)

1 PREFILLED SYRINGE(s) OF 0.4ML

79% OFF
Oriadali 40mg Injection
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₹5555

MRP: ₹26,249.00

Inclusive of all taxes

79% Off

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1 Prefilled Syringe(s) Of 0.4ml

1 Prefilled Syringe(s) Of 0.4ml

₹ 5555.0/Unit
Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
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Salt Composition

ADALIMUMAB

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SHILPA BIOSCIENCES

Prepaid Only. Non-Returnable.

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Introduction

Oriadali 40mg Injection contains the active ingredient Adalimumab. It is an antirheumatic agent that belongs to the TNF (tumour necrosis factor) inhibitor class of medications. It is used alone or with other medications to relieve the symptoms of certain autoimmune disorders. It is used to treat rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function), polyarticular juvenile idiopathic arthritis (a condition that affects children in which the body attacks its own joints, causing pain, swelling, loss of function, and delays in growth and development).

It is also indicated to treat enthesitis-related arthritis, ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain and joint damage), axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin), plaque psoriasis,  hidradenitis suppurativa (a skin disease that causes pimple-like bumps in the armpits, groin, and anal area), Crohn’s disease, ulcerative colitis (a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum), and non-infectious uveitis (swelling and inflammation of different areas of the eye). 

Do not use Oriadali Injection if you are allergic to adalimumab or any of the other ingredients present in this medicine. Do not take this medicine if you have active tuberculosis or other severe infections. Do not consume this medicine if you have moderate or severe heart failure. Inform your physician of any active infections before starting treatment. Tell your doctor if you have lung problems, heart diseases, liver or kidney disorders before initiating the treatment. If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice about taking this medicine. Oriadali 40 mg Price is same in all the locations in India.

Uses

  • Rheumatoid arthritis

  • Polyarticular juvenile idiopathic arthritis

  • Enthesitis-related arthritis

  • Ankylosing spondylitis

  • Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis

  • Psoriatic arthritis

  • Plaque psoriasis

  • Hidradenitis suppurativa

  • Crohn’s disease

  • Ulcerative colitis

  • Non-infectious uveitis

How Oriadali 40mg Injection Works

The active ingredient in this Odiadali medicine is a human monoclonal antibody. Monoclonal antibodies are proteins that bind to specific targets. The target of Oriadali 40mg Injection is a protein called tumour necrosis factor (TNFα), which is involved in the immune (defence) system and at increased levels in inflammatory diseases.  By binding TNFα, Humira reduces inflammation in these diseases.

Interaction of Oriadali 40mg Injection with other drugs


Taking Oriadali 40mg Injection (adalimumab) with any of the following medicines can change the effect of either of them and may increase the risk of serious side effects.

Other biologic immunosuppressants such as Infliximab or Etanercept (Injection Route) Life-threatening
Do not use together.
Concomitant use may greatly increase the risk of serious infections and immune suppression.

Anakinra or Abatacept (Injection Route) Life-threatening
Avoid using together.
Taking these medicines with adalimumab may significantly increase the risk of infections without added benefit.

Live vaccines such as BCG, MMR, or Varicella (Injection Route) Life-threatening
Do not receive during treatment.
This medicine suppresses the immune system and may increase the risk of serious infections after vaccination.

Methotrexate (Oral/Injection Route) Moderate
Use under medical supervision.
This combination is commonly used but may increase the risk of infections and requires monitoring.

Corticosteroids such as Prednisolone or Dexamethasone (Oral/Injection Route) Moderate
Use with caution.
Concomitant use may further weaken the immune system and increase infection risk.

Immunosuppressants such as Azathioprine or Cyclosporine (Oral/Injection Route) Moderate
Use carefully.
Taking these medicines together may increase the risk of infections and other immune-related complications.

Storage Conditions

  • Store in a refrigerator (2°C – 8°C).

  • Do not freeze.

  • Protect the medicine from light and excessive moisture.

  • Keep the medicine out of reach of children and pets

How to consume Oriadali 40mg Injection

Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severity and other factors. Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.  

This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or another healthcare professional will train you to use this injection. Do not self-administer this injection until you get trained. Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severeity and other factors.

Safety Advices

Pregnancy-Consult Your Doctor

Pregnancy

Consult Your Doctor

Do not take Oriadali 40mg Injection during pregnancy unless your doctor says. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose. 

Breast Feeding-Consult Your Doctor

Breast Feeding

Consult Your Doctor

Oriadali 40mg Injection can be used during breastfeeding. However, inform your physician if you are breastfeeding.

Lungs-Consult Your Doctor

Lungs

Consult Your Doctor

Oriadali 40mg Injection should be taken cautiously in patients with lung problems. Inform your physician of any lung diseases before initiating treatment.   

Liver-Consult Your Doctor

Liver

Consult Your Doctor

Oriadali 40mg Injection should be taken cautiously in patients with liver problems. Inform your physician if you have any liver diseases before initiating the treatment.  

Alcohol-Consult Your Doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol is safe during treatment with Oriadali 40mg Injection. Consult your doctor for more advice.  

Driving-Consult Your Doctor

Driving

Consult Your Doctor

Oriadali 40mg Injection may have a small effect on your ability to drive, cycle or use machines. Room-spinning sensation and vision disturbances may occur after taking this medicine.

Side Effects

Oriadal 40 mg Injection side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

  • Injection site reactions

  • Rash

  • Headache

  • Sinusitis

  • Upper respiratory infections

  • Fever

Serious 

  • Heart problems

  • Abnormal heart beat

  • Severe skin reactions

  • GI bleeding

  • Abnormal blood count values

  • Liver injury

  • Bone problems

  • Infections

  • Severe respiratory problems

Expert Tips

  1. Vaccine caution: Avoid live vaccines while taking this medicine, as some vaccines can cause infections — always check with your doctor before vaccination.

  2. Hepatitis B risk: Inform your doctor if you have hepatitis B or have previously had it, as this medicine may reactivate the infection.

  3. Self-injection guidance: If instructed to inject at home, ensure you fully understand the proper technique and dosage instructions.

  4. Injection site rotation: Use different body areas for each injection, avoiding red, bruised, or tender skin, and keep track of injection sites.

  5. Missed dose instructions: Take a missed dose as soon as you remember, but skip it if it’s almost time for the next one, never double the dose.

Frequently Asked Questions(FAQs)

Q1.

How long does it take for Oriadali 40mg Injection to start working?

The response to Oriadali 40mg Injection can vary among individuals and the condition being treated. Some individuals may experience symptom improvement within a few weeks, while others may take longer. It is important to follow the healthcare provider's instructions and allow sufficient time for the medication to take effect.

Q2.

Can Oriadali 40mg Injection increase the risk of infections?

Oriadali 40mg Injection may increase the risk of serious bacterial, viral, or fungal infections. It is essential to promptly report any signs of infection to a healthcare provider while taking this medicine. Inform your physician if you have or had any active infections.

Q3.

What are the common side effects of Oriadali 40mg Injection?

Common side effects of Oriadali 40mg Injection may include injection site reactions, such as pain, redness, or swelling. Other possible side effects include headaches, upper respiratory infections, nausea, and rash. Serious side effects are rare but can occur.

Q4.

How long can I take Oriadali 40mg Injection?

The duration of Oriadali 40mg Injection treatment can vary depending on the individual's condition and response to the medication. In some cases, this medicine may be used as long-term maintenance therapy, while treatment duration may be shorter in others. It is important to follow the healthcare provider's guidance regarding the appropriate duration of treatment.

Q5.

Can Oriadali 40mg Injection be used in individuals with kidney or liver impairment?

Oriadali 40mg Injection may require dosage adjustments or caution in individuals with kidney or liver impairment. Healthcare providers will assess the patient's situation and determine the appropriate dosage based on renal and hepatic function.

Q6.

What is Oriadali 40mg injection used for?

Oriadal 40 mg Injection is used to help manage certain cancers by slowing or stopping the growth of cancer cells.

Fact Box

Molecule name: 

Adalimumab

Therapeutic class:

  Antirheumatic agent, Monoclonal antibody

Pharmacological class:

TNF inhibitors

    Indications: 

  1.  Rheumatoid arthritis 

   2. Polyarticular juvenile idiopathic arthritis 

   3. Enthesitis-related arthritis 

   4. Ankylosing spondylitis

   5. Axial spondyloarthritis without radiographic        

   6. Psoriatic arthritis

   7. Plaque psoriasis

   8. Hidradenitis suppurativa

   9. Crohn’s disease

   10. Ulcerative colitis

   11. Non-infectious uveitis

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1018.

  2. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 213.

  3. AbbVie Ltd, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on July 2023], https://www.medicines.org.uk/emc/files/pil.2150.pdf

  4. AbbVie Inc, US Food and Drug Administration, [ Revised on Feb 2021] [ Accessed on July 2023], https://www.rxabbvie.com/pdf/humira.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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