Quick Summary
Oriaxon SB 1.5gm Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
₹97
MRP: ₹160.71
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1 VIAL(s)
40% OFF
₹97
MRP: ₹160.71
Inclusive of all taxes
40% Off
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Efectal S 1.5gm Injection
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Introduction
Oriaxon SB 1.5gm Injection is a combination medication containing ceftriaxone, an antibiotic from the cephalosporin group, and sulbactam, a beta-lactamase inhibitor with antibacterial properties. This combination is effective against various bacterial infections. Do not take this medication if you are allergic to ceftriaxone, other cephalosporins, or penicillins. It is not recommended for premature babies or newborns (up to 28 days old) with blood issues, jaundice, or those under calcium-containing medications.
Before taking this medication, consult your healthcare provider if you have had calcium-containing medications, antibiotic-related diarrhoea, gut issues like colitis, liver or kidney issues, gallstones, kidney stones, anaemia, following a low-sodium diet, or experience symptoms like rash, blistering, or high fever. Transparent communication with your doctor about your medical history and medications is vital for safely using these injections.
Uses of Oriaxon SB 1.5gm Injection
- Bacterial infections
How Oriaxon SB 1.5gm Injection works
Oriaxon SB 1.5gm Injection is a combination of ceftriaxone and sulbactam, effective against multidrug-resistant bacteria. Ceftriaxone, an antibiotic, works by inhibiting the formation of the bacterial protective covering crucial for bacterial survival. Sulbactam, a beta-lactamase inhibitor, reduces resistance and enhances ceftriaxone's effectiveness against bacteria.
Interaction of Oriaxon SB 1.5gm Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Efectal S 1500mg/1.5 gm injection and cause undesirable side effects.
Storage conditions
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Store below 25°C.
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Protect from light.
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Keep out of reach of children.
How to use Oriaxon SB 1.5gm Injection
Oriaxon SB 1.5gm Injection is given only in a hospital set up by a trained healthcare provider. This medication is injected into your muscle or your vein by your doctor. Your doctor will decide your most appropriate dosage based on age and physical circumstances.
Safety Advices
Pregnancy
If you are pregnant, think you may get pregnant, or are planning to have a baby, check with your doctor for advice before using this medicine. Oriaxon SB 1.5gm Injection is given to you only when it is considered essential by your doctor.
Breast Feeding
If breastfeeding, ask your doctor or pharmacist for advice before using this medicine. Oriaxon SB 1.5gm Injection is given to you only when it is considered essential by your doctor.
Lungs
Oriaxon SB 1.5gm Injection is generally safe and can be prescribed for patients with lung problems. Consult your physician if you have any lung diseases before starting the treatment.
Liver
Oriaxon SB 1.5gm Injection is used cautiously in patients with liver problems. Inform your doctor if you have liver disease before starting this treatment. Your physician will adjust your dose based on your liver condition and will be required to monitor you closely.
Alcohol
It is not recommended to take alcoholic beverages during the treatment since it can interact with alcohol and cause dizziness. Consult your doctor for more advice.
Driving
Oriaxon SB 1.5gm Injection can cause dizziness. Do not drive or operate machines if you are affected or feel dizzy after this injection. Check with your doctor for more advice.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious:
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Severe allergic reactions (rashes, itching, difficulty in breathing, fever)
Common:
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Irregularities in your white blood cell count and platelet count
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Loose stools or diarrhoea
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Alterations in liver function blood test
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Injection site pain
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Thrombophlebitis (inflammation of the vein)
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Injection site pain
Expert Tips
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This medicine is recommended only for children aged 1 year or older.
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It is used to treat bacterial infections, even those caused by resistant bacteria.
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Complete the full course of treatment, even if you start feeling better, to avoid the risk of the infection coming back stronger.
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Do not stop the medication early, as stopping too soon can cause bacteria to become resistant to the treatment.
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Diarrhoea may occur as a side effect. To reduce this, consider taking probiotics like yoghurt, fermented foods, or supplements.
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Contact your doctor immediately if you experience:
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Bloody stools
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Severe stomach cramps
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Take this medication with food and drink plenty of fluids to help prevent stomach upset.
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Stop the medicine and seek urgent medical help if you have:
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Itchy rash
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Swelling of the face, throat, or tongue
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Difficulty breathing
FAQs
Q1.
Why is sulbactam added to ceftriaxone in Oriaxon SB 1.5gm Injection?
Sulbactam is added to ceftriaxone to enhance its effectiveness against bacteria. Sulbactam acts as a beta-lactamase inhibitor, reducing bacterial resistance and allowing ceftriaxone to exert its antibacterial effects more efficiently. This combination of Oriaxon SB 1.5gm Injection helps combat infections caused by bacteria that might otherwise resist ceftriaxone alone.
Q2.
What is the contraindication of Oriaxon SB 1.5gm Injection?
Oriaxon SB 1.5gm Injection for injection is not recommended for patients allergic to cephalosporin antibiotics. Individuals with penicillin hypersensitivity may be prone to allergic cross-reactions.
Q3.
Is Oriaxon SB 1.5gm Injection safe for kidney failure?
Oriaxon SB 1.5gm Injection should be used with caution if you have a history of kidney function because of the elevated likelihood of severe adverse reactions.
Q4.
What precautions should I take before undergoing blood or urine tests while on Oriaxon SB 1.5gm Injection medication?
Inform the tester about your medication when taking blood or urine tests. Oriaxon SB 1.5gm Injection can affect urine test results and a blood test known as the coombs test.
Q5.
Are there specific precautions for diabetic patients while on Oriaxon SB 1.5gm Injection?
If you have diabetes, you should avoid certain blood glucose monitoring systems that might provide inaccurate readings during Oriaxon SB 1.5gm Injection treatment. If using such systems, carefully follow the instructions and inform your doctor. If necessary, consider alternative testing methods to ensure accurate results.
Fact Box
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Molecule Name: Ceftriaxone + Sulbactam |
Therapeutic class: Antibiotics |
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Pharmacological class:
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Indications: Bacterial infections
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References
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CP Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Jun 2022], [Accessed on 7th Oct 2023], https://www.medicines.org.uk/emc/product/1361/pil
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Nitin Lifesciences Ltd, US Food and Drug Administration (FDA), [Revised on Sep 2022], [Accessed on 7th Oct 2023], https://bluecrosslabs.com/wp-content/uploads/2021/01/EXTACEF-XL1_5g-Injection-PI-Sep2022.pdf
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KD Tripathi, Essentials of Medical Pharmacology, Antimicrobial drugs, 8th edition, 2019, 778
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Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Chemotherapy of Infectious Diseases,13th edition, 2018, 1033- 1036
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Sakshi Anil More
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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