Oxasted 50mg Injection belongs to the group of medications called platinum-based antineoplastic agents. It consists of the active ingredient Oxaliplatin. It is prescribed to treat stage 3 colon cancer after resectioning (surgical removal) of the primary tumor, metastatic colon and rectum cancer. It is used in combination with other anti-cancer medicines. Colorectal cancer is cancer that usually develops in the rectum and large intestine. It develops from the accumulation of various genetic mutations. Both environmental and genetic factors play a significant role in the origin of colorectal cancer. This medicine works against tumors that are resistant to cisplatin therapy.

The common side effects that are likely to be associated with Oxasted 50 mg Injection are a reduced number of blood cells, unpleasant sensation in the throat, diarrhea, nausea, vomiting, indigestion, heartburn, blood clots, blood in urine, high blood pressure, depression, insomnia, low calcium level. Inform your doctor if these side effects disturb or persist in you.

Inform your doctor if you are allergic to Oxasted 50 Injection and its ingredients. Before starting treatment with this medication, inform your physician if you have moderate or mild kidney problems, liver problems, or heart disorders. Tell your doctor about all the medicines you are taking, including vaccinations. It is not recommended for pregnant and breastfeeding women.

Oxasted injection uses are:

• Treatment of colon and rectal cancer.

Oxasted 50mg Injection damages the genetic material, such as DNA and RNA of the cancer cells, that interferes with the growth of cancer cells. It stops the growth and multiplication of cancer cells.

Inform your doctor about any medications you are taking or have taken before the treatment.

• Store at a temperature below 30°C.
• Protect from light.

Oxasted 50mg Injection is given by slow injection into one of your veins ( Oxasted dosage IV infusion) over 2 to 6 hours. Your physician will prescribe a Oxasted 50 mg dosage according to your body surface area.

Oxasted side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets the
 

Serious

• Abnormal bleeding or bruising
• Severe allergic reactions
• Continuous diarrhea and vomiting
• Sore throat and fever
• Irregular heartbeat
• Muscle pain and weakness
• Mouth ulcers
• Extreme tiredness and breathlessness
• Headache
• Altered mental function
• Blurred vision
• Seizures

Common

• A reduced number of blood cells
• Unpleasant sensation in the throat
• Diarrhea
• Nausea, vomiting
• High risk of infections
• Indigestion and heartburn
• Blood in urine
• Blood clots
• High BP
• Depression and insomnia
• Low levels of calcium in the blood

1. Hospira UK Limited, Electronic Medicines Compendium (EMC), [Revised on Dec 2020] [Accessed on 25th Jun 2021], https://www.medicines.org.uk/emc/files/pil.6286.pdf
2. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 837-920.